Results 51 to 60 of about 745,482 (386)

Group 2 Innate Lymphoid Cells Are Redundant in Experimental Renal Ischemia-Reperfusion Injury. [PDF]

, 2019
Acute kidney injury (AKI) can be fatal and is a well-defined risk factor for the development of chronic kidney disease. Group 2 innate lymphoid cells (ILC2s) are innate producers of type-2 cytokines and are critical regulators of homeostasis in ...
Cameron, Guy JM, Cautivo, Kelly M, Deshpande, Aniruddh V, Foster, Paul S, Hansbro, Philip M, Jiang, Simon H, Loering, Svenja, McKenzie, Andrew NJ, Molofsky, Ari B, Starkey, Malcolm R   +9 more
core   +4 more sources

Short-course IL-15 given as a continuous infusion led to a massive expansion of effective NK cells: implications for combination therapy with antitumor antibodies

Journal for ImmunoTherapy of Cancer, 2021
Background Full application of cytokines as oncoimmunotherapeutics requires identification of optimal regimens. Our initial effort with intravenous bolus recombinant human interleukin-15 (rhIL-15) was limited by postinfusional reactions.
Thomas A Waldmann, Kevin C Conlon, Sigrid P Dubois, Milos D Miljkovic, Thomas A Fleisher, Stefania Pittaluga, Jennifer Hsu-Albert, Bonita R Bryant, Michael N Petrus, Liyanage P Perera, Jürgen R Müller, Joanna H Shih   +11 more
doaj   +1 more source

Innate lymphoid cells in secondary lymphoid organs

Immunological Reviews, 2016
SummaryThe family of innate lymphoid cells (ILCs) has attracted attention in recent years as its members are important regulators of immunity, while they can also cause pathology. In both mouse and man, ILCs were initially discovered in developing lymph nodes as lymphoid tissue inducer (LTi) cells.
Bar-Ephraïm, JE, Mebius, Reina E.
openaire   +3 more sources

Possible role of GADD45γ methylation in diffuse large B-cell Lymphoma: Does it affect the progression and tissue involvement? [PDF]

, 2015
Objective: Diffuse large B-cell lymphoma (DLBCL) is the most common type of non-Hodgkin lymphoma among adults and is characterized by heterogeneous clinical, immunophenotypic, and genetic features.
Barış, İkbal Cansu, Bağcı, Gülseren, Can, Özge, Caner, Vildan, Doğu, Mehmet Hilmi, Hacıoğlu, Sibel, Keskin, Ali, Sarı, İsmail, Tepeli, Emre, Türk, Nilay Şen, Çetin, Ozan   +10 more
core   +2 more sources

Castle man disease: a case report and review of the literature

The Pan African Medical Journal, 2014
The Castleman disease (CD) is a rare disease of unknown etiology, characterized histologically by angiofollicular lymphoid hyperplasia. It comes in two forms, unicentric and multicentric.
Mounir Kettani, Nabil Touiheme, Hicham Attifi, Mounir Hmidi, Ali Boukhari, Mohamed Zalagh, Abdelhamid Messary   +6 more
doaj   +1 more source

Tertiary Lymphoid Structures: Diversity in Their Development, Composition, and Role

Journal of Immunology, 2021
Lymph node stromal cells coordinate the adaptive immune response in secondary lymphoid organs, providing both a structural matrix and soluble factors that regulate survival and migration of immune cells, ultimately promoting Ag encounter.
Catarina Gago da Graça, L. V. van Baarsen, R. Mebius   +2 more
semanticscholar   +1 more source

Enrichment of innate lymphoid cell populations in gingival tissue [PDF]

, 2018
Innate lymphoid cells (ILCs) are a population of lymphocytes that act as the first line of immunologic defense at mucosal surfaces. The ILC family in the skin, lungs, and gastrointestinal tissues has been investigated, and there are reports of individual
Adrados Planell, A., Brown, J.L., Butcher, J.P., Campbell, L., Culshaw, S., Malcolm, J.   +5 more
core   +2 more sources

[Innate lymphoid cells].

Medecine sciences : M/S, 2017
Innate Lymphoid Cells (ILC) are tissue-resident effector lymphocytes that differ from the B and T lymphocytes subsets since they lack specific antigen receptors derived from gene rearrangements. They can be divided into two groups, cytotoxic ILC (NK cells) which are dependent on the transcription factors Eomes and T-bet and produce IFN-γ, and helper ...
Crinier, Adeline, Viant, Charlotte, Girard-Madoux, Mathilde, Vivier, Eric   +3 more
openaire   +3 more sources

Oral manifestations leading to the diagnosis of acute lymphoblastic leukemia in a young girl

Journal of Indian Society of Pedodontics and Preventive Dentistry, 2012
Background: oral complications may be leukemia′s first presentation. Aim: to present a case of a young girl with a swelling on the face that led to the diagnosis of acute lymphoblastic leukemia is reported. Results: a 10-year old anemic girl was referred
B A Silva, CRB Siqueira, PHS Castro, S S Araújo, LER Volpato   +4 more
doaj   +1 more source

Tertiary lymphoid structures and B lymphocytes in cancer prognosis and response to immunotherapies

Oncoimmunology, 2021
Tertiary lymphoid structures (TLS) are ectopic cellular aggregates that resemble secondary lymphoid organs in their composition and structural organization.
Jacquelot N, T. J, Nutt Sl, Belz Gt
semanticscholar   +1 more source