Results 51 to 60 of about 563,178 (338)

Uveal lymphoid infiltrates: immunohistochemical evidence for a lymphoid neoplasia. [PDF]

British Journal of Ophthalmology, 1989
A 67-year-old man presented with a diffuse choroidal and ciliary body infiltrate, suggesting clinically and ultrasonographically a diffuse uveal melanoma. After enucleation both morphological and immunohistochemical data were highly suggestive of a diffuse, low-grade B cell lymphoma or lymphoplasmacytic immunocytoma.
Nancy L. Harris, David Ben-Ezra, Jose A. Sahel, Itzhak Hemo, Daniel M. Albert   +4 more
openaire   +2 more sources

B cell mechanobiology in health and disease: emerging techniques and insights into therapeutic responses

FEBS Letters, EarlyView.
B cells sense external mechanical forces and convert them into biochemical signals through mechanotransduction. Understanding how malignant B cells respond to physical stimuli represents a groundbreaking area of research. This review examines the key mechano‐related molecules and pathways in B lymphocytes, highlights the most relevant techniques to ...
Marta Sampietro, Marco Cellani, Cristina Scielzo   +2 more
wiley   +1 more source

Prevention of transplant rejection can tolerance be achieved with immunosuppressive treatment? [PDF]

, 1996
Successful solid organ transplantation is generally attributed to the increasingly precise ability of drugs to control rejection. However, it was recently shown that a few donor haematolymphoid cells can survive for decades in recipients of successful ...
Delaney, CP, Demetris, AJ, Murase, N, Starzl, TE   +3 more
core   +1 more source

A Rare Case of Primary Vulvar Diffuse Large B‐Cell Lymphoma: A Case Report

Clinical Case Reports
Primary vulvar diffuse large B‐cell lymphoma is a diagnostically challenging malignant tumor due to its low incidence and diverse clinical presentations. It has a good prognosis and is usually radio‐chemotherapy‐responsive.
M. Singh, S. Ngakhusi, A. Shrestha, P. Subedi, K. Khadka, H. P. Dhakal   +5 more
doaj   +1 more source

Single‐cell insights into the role of T cells in B‐cell malignancies

FEBS Letters, EarlyView.
Single‐cell technologies have transformed our understanding of T cell–tumor cell interactions in B‐cell malignancies, revealing new T‐cell subsets, functional states, and immune evasion mechanisms. This Review synthesizes these findings, highlighting the roles of T cells in pathogenesis, progression, and therapy response, and underscoring their ...
Laura Llaó‐Cid
wiley   +1 more source

Lymphoid Reconstruction and Vaccines

Biology of Blood and Marrow Transplantation, 2007
Allogeneic HSCT is the most reliable, robust, and effective cell-based biotherapy currently available to pediatric and adult patients with hematologic malignancies. The central role of donor-derived lymphocytes in mediating an effective antitumor effect, preventing and controlling opportunistic infections, and causing GVHD is well documented in animal ...
Hermann Einsele, Ronald E. Gress, Laurence J.N. Cooper, Krishna V. Komanduri   +3 more
openaire   +3 more sources

Systems biology drug screening identifies statins as enhancers of current therapies in chronic lymphocytic leukemia

Scientific Reports, 2020
Chronic lymphocytic leukemia (CLL) is a B lymphoid malignancy highly dependent on the microenvironment. Despite new targeted therapies such as ibrutinib and venetoclax, disease progression and relapse remain an issue.
Neus Gimenez, Rupal Tripathi, Ariadna Giró, Laia Rosich, Mònica López-Guerra, Irene López-Oreja, Heribert Playa-Albinyana, Fabian Arenas, José Manuel Mas, Patricia Pérez-Galán, Julio Delgado, Elias Campo, Judith Farrés, Dolors Colomer   +13 more
doaj   +1 more source

The epithelial barrier theory proposes a comprehensive explanation for the origins of allergic and other chronic noncommunicable diseases

FEBS Letters, EarlyView.
Exposure to common noxious agents (1), including allergens, pollutants, and micro‐nanoplastics, can cause epithelial barrier damage (2) in our body's protective linings. This may trigger an immune response to our microbiome (3). The epithelial barrier theory explains how this process can lead to chronic noncommunicable diseases (4) affecting organs ...
Can Zeyneloglu, Huseyn Babayev, Ismail Ogulur, Sena Ardicli, Yagiz Pat, Duygu Yazici, Bingjie Zhao, Lihong Chang, Xiaoqing Liu, Paolo D'Avino, Manru Li, Ceren Biçer, Fatma Hacer Kurtoğlu Babayev, Raja Dhir, Kari C. Nadeau, Marie‐Charlotte Brüggen, Mubeccel Akdis, Cezmi A. Akdis   +17 more
wiley   +1 more source

Editorial: tertiary lymphoid organs (TLOs): powerhouses of disease immunity [PDF]

, 2017
No abstract ...
Habenicht, Andreas J.R., Maffia, Pasquale, Mohanta, Sarajo, Yin, Changjun   +3 more
core   +2 more sources

High rate of complete responses to immune checkpoint inhibitors in patients with relapsed or refractory Hodgkin lymphoma previously exposed to epigenetic therapy

Journal of Hematology & Oncology, 2016
Options for patients with relapsed or refractory (R/R) classical Hodgkin lymphoma (cHL) after brentuximab vedotin (Bv) and autologous stem cell transplantation (ASCT) are limited.
Lorenzo Falchi, Ahmed Sawas, Changchun Deng, Jennifer E. Amengual, Donald S. Colbourn, Emily A. Lichtenstein, Karen A. Khan, Lawrence H. Schwartz, Owen A. O’Connor   +8 more
doaj   +1 more source