Results 111 to 120 of about 78,214 (186)

Tertiary lymphoid structures: Defining immune subtypes and enabling precision immunotherapy in nasopharyngeal carcinoma

Clinical and Translational Discovery, Volume 6, Issue 1, February 2026.
Fan Liu, Lei Xiong, Xia Yu, Mingfang Ji
wiley   +1 more source

Psoriatic Synovitis: Singularity and Potential Clinical Implications

Frontiers in Medicine, 2019
Psoriatic arthritis (PsA) is an immuno-inflammatory disease with a heterogeneous clinical presentation as affects musculoskeletal tissues (arthritis, enthesitis, spondylitis), skin (psoriasis) and, less frequently, eye (uveitis) and bowel (inflammatory ...
Raquel Celis, Andrea Cuervo, Julio Ramírez, Juan D. Cañete   +3 more
doaj   +1 more source

Podoplanin expressing macrophages and their involvement in tertiary lymphoid structures in mouse models of Sjögren’s disease

Frontiers in Immunology
Tertiary lymphoid structures (TLSs) are formed in tissues targeted by chronic inflammation processes, such as infection and autoimmunity. In Sjögren’s disease, the organization of immune cells into TLS is an important part of disease progression.
Aud-Malin Karlsson Hovd, Saba Nayar, Charlotte G. Smith, Premasany Kanapathippillai, Valentina Iannizzotto, Francesca Barone, Kristin Andreassen Fenton, Hege Lynum Pedersen   +7 more
doaj   +1 more source

Control of Dichotomic Innate and Adaptive Immune Responses by Artery Tertiary Lymphoid Organs in Atherosclerosis

Frontiers in Physiology, 2012
Tertiary lymphoid organs (TLOs) emerge in tissues in response to nonresolving inflammation such as chronic infection, graft rejection, and autoimmune disease. We identified artery TLOs (ATLOs) in the adventitia adjacent to atherosclerotic plaques of aged
Falk eWeih, Rolf eGräbner, Desheng eHu, Desheng eHu, Michael eBeer, Andreas Johann Habenicht   +5 more
doaj   +1 more source

Unveiling the myxofibrosarcoma tumor microenvironment: implications for immunotherapy

Frontiers in Immunology
Myxofibrosarcoma (MFS) is a rare and aggressive soft tissue sarcoma characterized by high genomic instability, resulting in high local recurrence rates and limited effective therapeutic options in advanced stages.
Cecilia Profumo, Cecilia Profumo, Massimiliano Grassi, Massimiliano Grassi, Valentina Rigo, Matteo Mascherini, Paola Monti, Giorgia Arcovito, Giorgia Anselmi, Laura Damele, Giorgia Timon, Danila Comandini, Michela Croce   +12 more
doaj   +1 more source

Tertiary lymphoid structures in cancer: immune mechanisms and clinical implications

MedComm
Cancer is a major cause of death globally, and traditional treatments often have limited efficacy and adverse effects. Immunotherapy has shown promise in various malignancies but is less effective in tumors with low immunogenicity or immunosuppressive ...
Siyu Wang, Hua Wang, Chenbei Li, Binfeng Liu, Shasha He, Chao Tu   +5 more
doaj   +1 more source

CXCR5- and CCR7-dependent lymphoid neogenesis in a murine model of chronic antigen-induced arthritis

, 2007
OBJECTIVE: Rheumatoid arthritis (RA) is a chronic inflammatory autoimmune disease with unknown etiology and only partially defined pathogenesis. The aim of this study was to establish a murine model of chronic arthritis in which the development of ...
Sven Hartmann, Peter K. Petrow, Uta E. Höpken, Martin Lipp, Antje M. Wengner, Rolf Bräuer, Höpken, U.E., Petrow, P.K., Hartmann, S., Lipp, M., Uta Schurigt, Schurigt, U., Bräuer, R., Wengner, A.M.   +13 more
core   +1 more source

Transplant of microbiota from Crohn’s disease patients to germ-free mice results in colitis

Gut Microbes
Although the role of the intestinal microbiota in the pathogenesis of inflammatory bowel disease (IBD) is beyond debate, attempts to verify the causative role of IBD-associated dysbiosis have been limited to reports of promoting the disease in ...
Irshad Ali Sheikh, Jared Bianchi-Smak, Daniel Laubitz, Gabriele Schiro, Monica T. Midura-Kiela, David G. Besselsen, Gayatri Vedantam, Sara Jarmakiewicz, Rafał Filip, Fayez K. Ghishan, Nan Gao, Pawel R. Kiela   +11 more
doaj   +1 more source

Human Lung Conventional Dendritic Cells Orchestrate Lymphoid Neogenesis during Chronic Obstructive Pulmonary Disease. [PDF]

Am J Respir Crit Care Med, 2020
Naessens T, Morias Y, Hamrud E, Gehrmann U, Budida R, Mattsson J, Baker T, Skogberg G, Israelsson E, Thörn K, Schuijs MJ, Angermann B, Melville F, Staples KJ, Cunoosamy DM, Lambrecht BN.   +15 more
europepmc   +1 more source

Lymphoid aggregation is not lymphoid neogenesis: Comment on the article by Klaasen et al [PDF]

Arthritis & Rheumatism, 2010
J. D. Cañete, Jose L. Pablos
openaire   +1 more source