Results 41 to 50 of about 42,543 (244)
Journal of Immunology, 1998 IL-2-activated NK cells exhibit cytotoxic activity against a wide variety of tumor cells in a non-MHC-restricted fashion and in the absence of prior sensitization. The molecular mechanisms that regulate the cytotoxicity and attachment of activated killer
G. Matsumoto +4 more
semanticscholar +1 more source
Mediators of Inflammation, 2016 Human Natural Killer (NK) cells are a specialized heterogeneous subpopulation of lymphocytes involved in antitumor defense reactions. NK cell effector functions are critically dependent on cytokines and metabolic activity.
Dante Miranda +7 more
doaj +1 more source
Journal of Immunology, 1991 In this study we investigated the expression of the 55 kDa (p55) and the 75 kDa (p75) TNF receptors in CD56+ NK cells and their role in NK and lymphokine-activated killer cells cell functions.
B. Naume +3 more
semanticscholar +1 more source
Local Anesthetics in Cancer: Mechanisms and Translational Perspectives
MedComm – Oncology, Volume 5, Issue 1, March 2026.Local anesthetics demonstrate multifaceted antitumor effects that collectively contribute to cancer suppression. Beyond canonical sodium channel blockade, these agents exert the following pharmacological actions: inhibition of tumor cell proliferation, suppression of migration and invasion, induction of proapoptotic pathways, attenuation of ...
Wan‐li Wang +4 more
wiley +1 more source
Journal of Immunology, 1988 We have investigated the ability of porcine-platelet-derived transforming growth factor-beta 1 (TGF-beta 1) to inhibit the generation of lymphokine-activated killer (LAK) cells by human rIL-2.
T. Espevik +3 more
semanticscholar +1 more source
Macrophages: Subtypes, Distribution, Polarization, Immunomodulatory Functions, and Therapeutics
MedComm, Volume 6, Issue 8, August 2025.Macrophages originate from the yolk sac, fetal liver, and bone marrow, differentiating into two main subtypes: M1‐like (proinflammatory) and M2‐like (anti‐inflammatory). These subtypes exhibit high plasticity, allowing them to transform in response to environmental cues or therapeutic interventions.
Mengyuan Peng +10 more
wiley +1 more source
Lymphokine‐Activated Killer Cells [PDF]
Annals of the New York Academy of Sciences, 1988 E A, Grimm +3 more
+5 more sources
IL-7 induces human lymphokine-activated killer cell activity and is regulated by IL-4.
Journal of Immunology, 1991 Induction of lymphokine-activated killer (LAK) activity by IL-2 has been described and characterized as broadly cytolytic activity against both fresh and cultured tumors. rIL-7 in the absence of IL-2 also induces LAK activity in human cells.
H. Stötter +4 more
semanticscholar +1 more source
A Review: Can Cytokines Induce Vascular Inflammation as a Sequela of Viral Infections?
Health Science Reports, Volume 8, Issue 7, July 2025.ABSTRACT Background and Aim There are many unknown consequences of viral infections. In this piece, we looked at one of these effects that influence the venous system of the body, vasculitis, an inflammation of the blood vessels. Discussion The study illustrates that viral infections attack host cells through viral proteins and surface receptors ...
Shahana Akhter Deena +4 more
wiley +1 more source
Food Science &Nutrition, Volume 13, Issue 6, June 2025.2′‐fucosyllactose prevented DSS‐induced intestinal inflammatory damage through exerting prebiotic capacity and regulating the intestinal immune response to gut microbiota. ABSTRACT Inflammatory bowel disease (IBD), a recurrent gastrointestinal disease, is characterized by dysbiosis and inflammation.
Jiamin Dong +4 more
wiley +1 more source