Results 51 to 60 of about 42,543 (244)

Continuous Indomethacin and Ranitidine with Interleukin-2 in Advanced Renal Carcinoma and Melanoma: A Preliminary Report

open access: yesCanadian Journal of Infectious Diseases, 1992
Experimental work has shown that during the development of tumours, host macrophages can deactivate natural killer cells and suppress lymphokine-activated killer cell development, apparently through prostaglandin E2 production.
Wilson C Mertens   +5 more
doaj   +1 more source

The mechanisms by which polyamines accelerate tumor spread

open access: yesJournal of Experimental & Clinical Cancer Research, 2011
Increased polyamine concentrations in the blood and urine of cancer patients reflect the enhanced levels of polyamine synthesis in cancer tissues arising from increased activity of enzymes responsible for polyamine synthesis. In addition to their de novo
Soda Kuniyasu
doaj   +1 more source

Antigen‐Targeting Inserted Nanomicelles Guide Pre‐Existing Immunity to Kill Head and Neck Cancer

open access: yesAdvanced Science, Volume 12, Issue 18, May 15, 2025.
This study introduces a tumor‐targeted nanomicelle platform (preS1‐pHLIP) that exploits pre‐existing antiviral immunity to combat heterogeneous cancers. By delivering viral antigens to label tumors as virus‐like targets, the nanomicelles activate antiviral B and T cells, triggering in situ tumor lysis.
Lizhuo Zhang   +16 more
wiley   +1 more source

Revolutionising Cancer Immunotherapy: Advancements and Prospects in Non‐Viral CAR‐NK Cell Engineering

open access: yesCell Proliferation, Volume 58, Issue 4, April 2025.
This manuscript provides a comprehensive overview of the state‐of‐the‐art in non‐viral CAR‐NK cell engineering, highlighting its potential to revolutionise cancer treatment. ABSTRACT The recent advancements in cancer immunotherapy have spotlighted the potential of natural killer (NK) cells, particularly chimeric antigen receptor (CAR)–transduced NK ...
Zhaokai Zhou   +18 more
wiley   +1 more source

Biological processes and factors involved in soft and hard tissue healing

open access: yesPeriodontology 2000, Volume 97, Issue 1, Page 16-42, February 2025.
Abstract Wound healing is a complex and iterative process involving myriad cellular and biologic processes that are highly regulated to allow satisfactory repair and regeneration of damaged tissues. This review is intended to be an introductory chapter in a volume focusing on the use of platelet concentrates for tissue regeneration.
Mark Bartold, Saso Ivanovski
wiley   +1 more source

Loss of the Cyclin-Dependent Kinase Inhibitor 1 in the Context of Brachyury-Mediated Phenotypic Plasticity Drives Tumor Resistance to Immune Attack

open access: yesFrontiers in Oncology, 2018
The acquisition of mesenchymal features by carcinoma cells is now recognized as a driver of metastasis and tumor resistance to a range of anticancer therapeutics, including chemotherapy, radiation, and certain small-molecule targeted therapies.
Duane H. Hamilton   +2 more
doaj   +1 more source

Polyporus umbellatus, A Precious Rare Fungus With Good Pharmaceutical and Food Value

open access: yesEngineering in Life Sciences, Volume 25, Issue 1, January 2025.
ABSTRACT Polyporus umbellatus is a rare porous fungus that exhibits notable pharmacological activities. Particularly, due to its diuretic properties, it is considered an important source of targeted drugs for the treatment of kidney disease. Extensive research has been conducted on this fungus, focusing not only on its challenging cultivation ...
Sizhu Ren   +5 more
wiley   +1 more source

Research progress of adoptive cell therapy in malignant glioma

open access: yesChinese Journal of Contemporary Neurology and Neurosurgery, 2016
Malignant glioma is the most common malignant tumor of central nervous system (CNS). Surgery is the main treatment method, supplemented by radiation and chemotherapy.
Meng LI
doaj  

Mannan-Binding Lectin Regulates Inflammatory Cytokine Production, Proliferation, and Cytotoxicity of Human Peripheral Natural Killer Cells

open access: yesMediators of Inflammation, 2019
Natural killer (NK) cells represent the founding members of innate lymphoid cells (ILC) and play critical roles in inflammation and the immune response. NK cell effector functions are regulated and fine-tuned by various immune modulators.
Jia Zhou   +8 more
doaj   +1 more source

Designing a Resilient Controller for Cancer Immunotherapy: Application to a Fractional‐Order Tumour‐Immune Model

open access: yesIET Systems Biology, Volume 19, Issue 1, January/December 2025.
In this paper, we propose a robust control method for the automatic treatment of targeted anti‐angiogenic molecular therapy based on multi‐input multi‐output (MIMO) nonlinear fractional and non‐fractional models using the backstepping (BS) approach.
Mohamadreza Homayounzade   +1 more
wiley   +1 more source

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