Results 71 to 80 of about 42,543 (244)
Organ Medicine, Volume 1, Issue 2, Page 70-84, December 2024.This article comprehensively analyzes the pivotal role of ezrin, an ERM protein family member, in diverse tumor types, highlighting its immunomodulatory capabilities and associations with tumor progression, immune cell infiltration, and therapeutic responses.
Ruiqi Chen +6 more
wiley +1 more source
Dynamic changes in macrophage polarization during the resolution phase of periodontal disease
Immunity, Inflammation and Disease, Volume 12, Issue 10, October 2024.This is the first translational studies to longitudinally assess the M/M2 MΦ profiles before and after therapy in periodontitis subjects and can serve as the first step in examining current treatment strategies to include investigations on the role of macrophage immune mediated regulatory networks governing periodontal disease pathogenesis.
Juhi R. Uttamani +6 more
wiley +1 more source
Australasian Journal of Dermatology, Volume 65, Issue 6, Page 491-504, September 2024.Abstract Stevens Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are severe cutaneous adverse reactions characterised by keratinocyte apoptosis, necroptosis and epidermal detachment. Several cytokines and cytotoxic proteins have been shown to be elevated in the blood and skin of SJS/TEN sufferers and biologics such as intravenous immune ...
Thomas Jonathan Stewart +2 more
wiley +1 more source
Natural killer cells in cancer immunotherapy
MedComm, Volume 5, Issue 7, July 2024.NK cells have cytotoxic functions against tumor cells especially through NKG2D receptor. This article reviews the mechanisms how tumors escape NK‐mediated killing and therapeutic strategies with NK cells and especially MICA/B–NKG2D axis. Finally, the recent innovative CAR‐NK/NKG2D CAR‐T and MICA/B vaccines in tumor were summarized.
DanRu Wang +4 more
wiley +1 more source
Journal of Immunology, 1988 Interleukin 2 (IL-2) stimulated the differentiation of human peripheral blood leukocytes into lymphokine-activated killer cells, as well as DNA synthesis of human T lymphocytes.
S. Beckner, W. Farrar
semanticscholar +1 more source
The Clinical Respiratory Journal, Volume 18, Issue 7, July 2024.The novel fusion protein melittin‐MIL‐2 may activate immune cells via activating the LFA‐1/ICAM‐1 and Fas/FasL pathways to enhance cytolytic activity, upregulating the production of IFN‐γ and perforin, and boosting LAK‐like and NK‐like killing activities.
Weize Gao +4 more
wiley +1 more source
Canadian Journal of Infectious Diseases, 1992 Despite the use of high dose chemoradiotherapy for the treatment of acute leukemia. relapse continues to be a major cause of death in patients given an autologous bone marrow transplant.
Hans-Georg Klingemann +3 more
doaj +1 more source
Acetylshikonin suppresses diffuse large B-Cell Lymphoma cell growth by targeting the T-lymphokine-activated killer cell-originated protein kinase signalling pathway. [PDF]
Bioengineered, 2022 Cui J +7 more
europepmc +1 more source
Transplantation and Adoptive Cellular Therapy of Cancer: The Role of T-Cell Growth Factors
Cell Transplantation, 1993 The ability to transfer cultured lymphocytes required the availability and the understanding of the use of the T-cell growth factors IL-2, IL-4, IL-7, and IL-12.
Michael T. Lotze M.D.
doaj +1 more source
Oxidized-Desialylated Low-Density Lipoprotein Inhibits the Antitumor Functions of Lymphokine Activated Killer Cells [PDF]
, 2021 Jesús S. Aguilar Díaz de león +3 more
openalex +1 more source