Transplantation and Adoptive Cellular Therapy of Cancer: The Role of T-Cell Growth Factors
Cell Transplantation, 1993 The ability to transfer cultured lymphocytes required the availability and the understanding of the use of the T-cell growth factors IL-2, IL-4, IL-7, and IL-12.
Michael T. Lotze M.D.
doaj +1 more source
Susceptibility to LAK-mediated Cytotoxicity of Multidrug-resistant Variants of the Human RAJI Cell Line is Not Related to Expression of Major Cellular Adhesion Molecules [PDF]
, 1993 Author Institution: Department of Biology, Oberlin CollegeThe association of multidrug resistance (MDR) with resistance to lysis by natural killer (NK) and lymphokine-activated killer (LAK) cells is controversial.
Treichel, Robin S.
core
Regulatory effects of lipoprotein lipase on proliferative and cytotoxic activity of NK cells
Journal of Lipid Research, 1996 Lipoprotein lipase (LPL) induced, in a dose-dependent fashion, a 2-fold and 11-fold increase in the proliferative response of peripheral blood lymphocytes (PBL) at 48 and 72 h, respectively; a 4- and 12-fold increase in natural killer (NK) cells ...
J B De Sanctis, I Blanca, N E Bianco
doaj
Acetylshikonin suppresses diffuse large B-Cell Lymphoma cell growth by targeting the T-lymphokine-activated killer cell-originated protein kinase signalling pathway. [PDF]
Bioengineered, 2022 Cui J +7 more
europepmc +1 more source
NKR-P1A is a target-specific receptor that activates natural killer cell cytotoxicity. [PDF]
, 1995 NKR-P1A is a lectinlike surface molecule expressed on rat natural killer (NK) cells. NKR-P1A has structural and functional features of an activating NK cell receptor, but a requirement for NKR-P1A in target cell lysis has not been determined.
Nakamura, MC +3 more
core
Short communication: NKG2C+ NK cells contribute to increases in CD16+CD56- cells in HIV type 1+ individuals with high plasma viral load. [PDF]
, 2012 Chronic HIV-1 infection results in the expansion of both NKG2C+ and CD16+CD56- human natural killer cells. NKG2C+ cells proliferate in response to human cytomegalovirus (HCMV) and expansion of the dysfunctional CD56-CD16+ natural killer (NK) cells is ...
Bower, Mark +5 more
core +1 more source
Natural Killer cells responsiveness to physical esercise: a brief review [PDF]
, 2013 Natural killer cells (NK) are a group of peripheral blood lymphocytes which display cytotoxic ac- tivity against a wide range of tumour cells. They are a consistent part of the inflammatory re- sponse that is activated when either internal or external ...
Concu A. +4 more
core +1 more source
Dlgh1 coordinates actin polymerization, synaptic T cell receptor and lipid raft aggregation, and effector function in T cells. [PDF]
, 2005 Lipid raft membrane compartmentalization and membrane-associated guanylate kinase (MAGUK) family molecular scaffolds function in establishing cell polarity and organizing signal transducers within epithelial cell junctions and neuronal synapses. Here, we
Miceli, M Carrie +5 more
core
LymphokineâActivated Killer Cells [PDF]
Annals of the New York Academy of Sciences, 1988 William G. Loudon +3 more
openaire +3 more sources
Correlation study of PBK/TOPK expression, prognosis, and immune infiltration in breast cancer
Scientific ReportsPDZ-binding kinase/T-lymphokine-activated killer-cell-originated protein kinase (PBK/TOPK) is a serine-threonine protein kinase. This study aimed to investigate the expression pattern, prognostic significance, and relationship with tumor immune ...
Bingxin Li +8 more
doaj +1 more source