Results 21 to 30 of about 23,347 (241)
Peritoneal exudate macrophages in guinea pigs and peripheral blood monocytes in man are the most readily available cells sensitive to the migration-inhibiting factor(s) (MIF) induced by tuberculin or insoluble concanavalin A in supernatants of stimulated lymphocyte cultures.
Wilhelm Friedrich +2 more
+5 more sources
Introduction:Coxiella (C.) burnetii, the aetiological agent of Q fever, is able to modulate the macrophage/T-lymphocyte axis in an infected organism and impair synthesis of monokines and lymphokines.
Małaczewska Joanna +6 more
doaj +1 more source
T lymphocytes from patients with primary biliary cirrhosis produce reduced amounts of lymphotoxin, tumor necrosis factor and interferon-gamma upon mitogen stimulation [PDF]
Primary biliary cirrhosis (PBC) is considered an autoimmune disease characterized by destruction of small intrahepatic bile ducts by lymphocytes. Altered functions of these lymphocytes might reflect an abnormal immune response leading to tissue damage ...
Eisenburg, Josef +9 more
core +1 more source
Cytokines as determinants of disease and disease interactions
The immune response to pathogens results in both host resistance and immunopathology. Cytokines and in particular those lymphokines produced by Th1 and Th2 cells play a key role in determining the balance between these two immunologic outcomes.
A. Sher +6 more
doaj +1 more source
We have previously demonstrated that weekly treatment of female prediabetic NOD mice with a low dose of the histone deacetylase inhibitor Trichostatin A (TSA) bestowed long-lasting, irreversible protection against autoimmune diabetes. Herein we show that
Arathi Jayaraman +2 more
doaj +1 more source
Impact Of Dietary Measures In Autoimmune Diseases
The immune system of an individual upon activation by antigens produces response to pathogenic microorganisms their products and to body self-antigens.
Nasim Karim
doaj +1 more source
A combination of soluble helper factors bypasses the requirement for stimulator cells and induces nonspecific cytotoxic T cell responses [PDF]
The specificity of cytotoxic T lymphocyte (CTL) responses generated in the presence of lymphokines was studied. Thymic responder cells were activated in the presence of stimulator cells that differed in their metabolic activity.
Dröge, W., Falk, Werner, Männel, D. N.
core +1 more source
Fluorescence flow cytometry was employed to assess the potential of a vital dye, hydroethiedine, for use in the detection and monitoring of the viability of hemoparasites in infected erythrocytes, using Babesia bovis as a model parasite.
W. C. Davis +3 more
doaj +1 more source
New simplified molecular design for functional T cell receptor [PDF]
We have produced a chimeric single-chain T cell receptor (TcR) that combines the specific antibody recognition function and TcR/CD3 signaling properties within the same polypeptide chain.
Clevers +23 more
core +1 more source
Interleukin-2 in Renal Cell Carcinoma: A Has-Been or a Still-Viable Option?
Modulation of the immune response plays an important role in the natural history of renal cell carcinoma. Spontaneous regression of metastases has been well documented in a small percentage of patients after they undergo de-bulking nephrectomy without ...
Asim Amin, Richard L White
doaj +1 more source

