Modulation of human lymphocyte function by C3a and C3a(70-77). [PDF]
Human C3a and the synthetic octapeptide C3a (70-77), which retains the activities of an anaphylatoxin, inhibit in a concentration-dependent manner the generation of leukocyte inhibitory factor (LIF) activity by human mononuclear leukocytes and T ...
Goetzl, EJ, Payan, DG, Trentham, DE
core
Cytokines of Birds: Conserved Functions [PDF]
Targeted disruptions of the mouse genes for cytokines, cytokine receptors, or components of cytokine signaling cascades convincingly revealed the important roles of these molecules in immunologic processes. Cytokines are used at present as drugs to fight
Göbel, Thomas W. F.+4 more
core +1 more source
Dynamic changes in macrophage polarization during the resolution phase of periodontal disease
This is the first translational studies to longitudinally assess the M/M2 MΦ profiles before and after therapy in periodontitis subjects and can serve as the first step in examining current treatment strategies to include investigations on the role of macrophage immune mediated regulatory networks governing periodontal disease pathogenesis.
Juhi R. Uttamani+6 more
wiley +1 more source
Modulation of Functional Activities of Chicken Heterophils by Recombinant Chicken IFN-γ [PDF]
The objective of the present studies was to examine the in vitro effects of recombinant chicken interferon-γ (rChIFN-γ) on shape change, phagocytosis, and the oxidative/nonoxidative killing activities of day-old chicken heterophils.
B. Kaspers+12 more
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Abstract Stevens Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are severe cutaneous adverse reactions characterised by keratinocyte apoptosis, necroptosis and epidermal detachment. Several cytokines and cytotoxic proteins have been shown to be elevated in the blood and skin of SJS/TEN sufferers and biologics such as intravenous immune ...
Thomas Jonathan Stewart+2 more
wiley +1 more source
Suppression of allograft rejection with FK506: I. prolonged cardiac and liver survival in rats following short-course therapy [PDF]
Heterotopic heart and orthotopic liver grafts from ACI donors were transplanted to Lewis rat recipients that were treated with a 3 (or 4) day course of FK506 IM that was started on postoperative day 0, 2, 3, 4, 5, or 6.
Cramer, DV+5 more
core +1 more source
Guinea pigs sublethally infected with aerosolized Legionella pneumophila develop humoral and cell-mediated immune responses and are protected against lethal aerosol challenge. A model for studying host defense against lung infections caused by intracellular pathogens. [PDF]
We have employed the guinea pig model of L. pneumophila infection, which mimics Legionnaires' disease in humans both clinically and pathologically, to study humoral and cell-mediated immune responses to L.
Breiman, RF, Horwitz, MA
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Reciprocal expression of interferon gamma or interleukin 4 during the resolution or progression of murine leishmaniasis. Evidence for expansion of distinct helper T cell subsets. [PDF]
We purified poly(A)+ mRNA from the spleen and lymph nodes at designated times after infection with Leishmania major in genetically susceptible BALB/c and resistant C57BL/6 mice.
Coffman, RL+4 more
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Th-1 cytokines gene polymorphism in human brucellosis [PDF]
Brucellosis is a worldwide zoonosis. Infection with Brucella species results in the activation of cell-mediated immune response. The interaction between Th1and Th2 cytokines determines the outcome of disease.
احمدی نژاد, زهرا+7 more
core +1 more source
An International Symposium organized as the VIth Annual Inflammation Meeting by the Department of Rheumatology, University of Birmingham.
openaire +2 more sources