Role of protein synthesis in the activation of cytotoxic mouse macrophages by lymphokines. [PDF]
, 1984 The role of protein synthesis during the activation of macrophages (Mφ) by lymphokines (LK) was studied. Peritoneal murine macrophages elicited by proteose-peptone (pMφ) were activated with LK (supernatants from normal mouse spleen cells pulsed with ...
Varesio, L +5 more
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V-region-related and -unrelated immunosupression accompanying infections
Memorias do Instituto Oswaldo Cruz, 1992 This paper discusses current evidence for the relationship between polyclonal lymphocyte activation, specific immunossupression with decreased resistance, and autoimmune pathology, that are all often found associated with infections by a variety of virus,
Mario Arala-Chaves +4 more
doaj +1 more source
B cell maturation factor (BMF): a lymphokine or family of lymphokines promoting the maturation of B lymphocytes. [PDF]
, 1984 Two in vitro B cell tumor lines have been used to characterize and partially purify a lymphokine, or family of lymphokines, from monoclonal helper T cell immune response supernatants.
Paige, C J, Sidman, C L, Schreier, M H
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Crosstalk between T lymphocyte and extracellular matrix in tumor microenvironment
Frontiers in ImmunologyThe extracellular matrix (ECM) is a complex three-dimensional structure composed of proteins, glycans, and proteoglycans, constituting a critical component of the tumor microenvironment.
Die Lv +8 more
doaj +1 more source
Ultra‐Processed Foods and Markers of Systemic Inflammation in Children
Food Science &Nutrition, Volume 13, Issue 9, September 2025.Illustration showing the association between ultra‐processed foods intake and systemic inflammation, measured with cytokines levels in children. ABSTRACT Diets high in ultra‐processed foods (UPF) have been associated with negative health outcomes in adults; however, UPF's impact on children's health and their underlying mechanisms remain underexplored,
Camila Awad +8 more
wiley +1 more source
Neurobiology of Disease, 2017 Multiple sclerosis is a T cell mediated chronic demyelinating disease of the central nervous system. Although currently available therapies reduce relapses, they do not facilitate tolerization of myelin antigen-specific T lymphocytes to ensure prolonged ...
Arathi Jayaraman +4 more
doaj +1 more source
H1N1 with fatal viral septicemia in a normal child: A case report
Respiratory Medicine Case Reports, 2020 Background: Regardless of the agent, the inflammatory response is interconnected with infection. Mostly the initial response to infection is severe sepsis and characterized by a pro-inflammatory state, which then progresses to an anti-inflammatory state ...
Ahmed Rezk Ahmed, M.D.
doaj +1 more source
Macrophages: Subtypes, Distribution, Polarization, Immunomodulatory Functions, and Therapeutics
MedComm, Volume 6, Issue 8, August 2025.Macrophages originate from the yolk sac, fetal liver, and bone marrow, differentiating into two main subtypes: M1‐like (proinflammatory) and M2‐like (anti‐inflammatory). These subtypes exhibit high plasticity, allowing them to transform in response to environmental cues or therapeutic interventions.
Mengyuan Peng +10 more
wiley +1 more source
T cell lymphokines modulate bFGF-induced smooth muscle cell fibrinolysis and migration [PDF]
, 1997 Smooth muscle cell (SMC) fibrinolysis is necessary for SMC migration. To determine whether the T cell lymphokines interleukin 4 (IL-4) and interferon-gamma (IFN-gamma) modulate SMC fibrinolysis and migration induced by basic fibroblast growth factor ...
W. Wang +4 more
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Lymphokine-induced cytotoxicity: requirement of two lymphokines for the induction of optimal cytotoxic response [PDF]
, 1985 Lymphokines induce the generation of cytotoxic cells (LICC) in the absence of antigenic or mitogenic stimulation. In the present study, we have demonstrated that at least two lymphokines are involved.
Malek, T R +3 more
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