Results 41 to 50 of about 2,347,326 (232)

Origin and pathogenesis of nodular lymphocyte–predominant Hodgkin lymphoma as revealed by global gene expression analysis [PDF]

, 2008
The pathogenesis of nodular lymphocyte–predominant Hodgkin lymphoma (NLPHL) and its relationship to other lymphomas are largely unknown. This is partly because of the technical challenge of analyzing its rare neoplastic lymphocytic and histiocytic (L&H ...
Brune, Verena, Bräuninger, Andreas, Döring, Claudia, Eckerle, Susan, Falini, Brunangelo, Hansmann, Martin-Leo, Heydebreck, Anja von, Klapper, Wolfram, Küppers, Ralf, Metzler, Dirk, Pfeil, Ines, Tiacci, Enrico, van Noesel, Carel J. M.   +12 more
core   +1 more source

Burkitt-like lymphoma with 11q aberration: a germinal center-derived lymphoma genetically unrelated to Burkitt lymphoma

Haematologica, 2019
Burkitt-like lymphoma with 11q aberration is characterized by pathological features and gene expression profile resembling those of Burkitt lymphoma but lacks the MYC rearrangement and carries an 11q-arm aberration with proximal gains and telomeric ...
Blanca Gonzalez-Farre, Joan Enric Ramis-Zaldivar, Julia Salmeron-Villalobos, Olga Balagué, Verónica Celis, Jaime Verdu-Amoros, Ferran Nadeu, Constantino Sábado, Antonio Ferrández, Marta Garrido, Federico García-Bragado, María Dolores de la Maya, José Manuel Vagace, Carlos Manuel Panizo, Itziar Astigarraga, Mara Andrés, Elaine S. Jaffe, Elias Campo, Itziar Salaverria   +18 more
doaj   +1 more source

Evolution in the Definition of Follicular Lymphoma and Diffuse Large B-Cell Lymphoma: A Model for the Future of Personalized Medicine

Hemato, 2022
The definitions of follicular lymphoma (FL) and diffuse large B-cell lymphoma (DLBCL) are evolving in the era of personalized medicine. Early stages of the evolution of FL have been recognized. Two histological manifestations of early lesions are in situ
Elaine S. Jaffe, Antonino Carbone
doaj   +1 more source

A Probabilistic Classification Tool for Genetic Subtypes of Diffuse Large B Cell Lymphoma with Therapeutic Implications.

Cancer Cell, 2020
The development of precision medicine approaches for diffuse large B cell lymphoma (DLBCL) is confounded by its pronounced genetic, phenotypic, and clinical heterogeneity. Recent multiplatform genomic studies revealed the existence of genetic subtypes of
George W. Wright, D. Huang, J. Phelan, Zana Coulibaly, S. Roulland, R. Young, James Q Wang, R. Schmitz, Ryan D. Morin, Jeffrey Tang, A. Jiang, Aleksander Bagaev, O. Plotnikova, N. Kotlov, Calvin A. Johnson, W. Wilson, D. Scott, L. Staudt   +17 more
semanticscholar   +1 more source

Primary extranodal lymphomas - spectrum of distribution and morphology with immunophenotyping: A 3-year institutional study

Medical Journal of Dr. D.Y. Patil University, 2015
Background: Malignant lymphomas arising in extranodal sites are intriguing. The histological types of lymphomas vary from one site to another.
Chinnam Aparna, Inuganti Venkata Renuka, Muthyala Rajani, Garikapati Sailabala, Parvatala Annapurna   +4 more
doaj   +1 more source

Targeting the tumor microenvironment in B-cell lymphoma: challenges and opportunities

Journal of Hematology & Oncology, 2021
B-cell lymphoma is a group of hematological malignancies with high clinical and biological heterogeneity. The pathogenesis of B-cell lymphoma involves a complex interaction between tumor cells and the tumor microenvironment (TME), which is composed of ...
Yingyue Liu, Xiangxiang Zhou, Xin Wang
semanticscholar   +1 more source

Long-term safety and activity of axicabtagene ciloleucel in refractory large B-cell lymphoma (ZUMA-1): a single-arm, multicentre, phase 1-2 trial.

The Lancet Oncology, 2019
BACKGROUND Axicabtagene ciloleucel is an autologous anti-CD19 chimeric antigen receptor (CAR) T-cell therapy. In the previous analysis of the ZUMA-1 registrational study, with a median follow-up of 15·4 months (IQR 13·7-17·3), 89 (82%) of 108 assessable ...
F. Locke, A. Ghobadi, C. Jacobson, D. Miklos, L. Lekakis, O. Oluwole, Yi Lin, I. Braunschweig, B. Hill, J. Timmerman, A. Deol, P. Reagan, P. Stiff, I. Flinn, U. Farooq, A. Goy, P. Mcsweeney, J. Muñoz, T. Siddiqi, J. Chavez, A. Herrera, N. Bartlett, J. Wiezorek, L. Navale, A. Xue, Yi-zhou Jiang, A. Bot, J. Rossi, Jenny J. Kim, W. Go, S. Neelapu   +30 more
semanticscholar   +1 more source

Usefulness of Immunoglobulin Light-Chain Restriction on Immunocytochemical Double Staining for the Cytological Diagnosis of B Cell Non-Hodgkin's Lymphoma [PDF]

, 2012
Objective: We examined the usefulness of light-chain restriction (LCR) on immunocytochemical double staining (IDS) for cytological diagnosis. Study Design: We investigated LCR on IDS in 40 patients with proliferative lymphatic disorders (23 with B cell ...
Mano, Shyouhe, Nakamura, Satoko, Orita, Yorihisa, Sato, Yasuharu, Shimoura, Yasumasa, Takata, Katsuyoshi, Yoshino, Tadashi   +6 more
core   +1 more source

Contribution of immunocytochemistry to the diagnosis of usual and unusual lymphoma cases

Journal of Cytology, 2018
Some of the limitations of fine needle aspiration (FNA) in the cytodiagnosis of lymphoma include problems encountered in differentiating reactive hyperplasia from low-grade non-Hodgkin lymphoma (NHL), lower cytodiagnostic accuracy for NHL with a ...
Dilip K Das
doaj   +1 more source

Identification of highly methylated genes across various types of B-cell non-hodgkin lymphoma. [PDF]

PLoS ONE, 2013
Epigenetic alterations of gene expression are important in the development of cancer. In this study, we identified genes which are epigenetically altered in major lymphoma types.
Nicole Bethge, Hilde Honne, Vera Hilden, Gunhild Trøen, Mette Eknæs, Knut Liestøl, Harald Holte, Jan Delabie, Erlend B Smeland, Guro E Lind   +9 more
doaj   +1 more source