The grading of lymphovascular space invasion in endometrial carcinoma [PDF]
This study was conducted to elucidate the prognostic significance of a three-grade system for lymphovascular space invasion (LVSI).The prognostic significance of the grading of LVSI as compared with other pathologic variables was evaluated in a study of 303 Japanese women with endometrial carcinoma.
T, Hachisuga +9 more
openaire +2 more sources
ABSTRACT Objective To evaluate oncological outcomes and their predictors following salvage oropharyngectomy. Methods This single‐center retrospective study included patients who underwent a salvage oropharyngectomy in an irradiated neck for recurrent or metachronous oropharyngeal squamous cell carcinoma (OPSCC) between 2014 and 2023.
Jade Saykaly +8 more
wiley +1 more source
Background: Cyclin D1, a member of the cyclin protein family, is instrumental in the cell cycle due to its influence on the progression from G1 to the S phase. Its overexpression causes reduced doubling time and is also associated with clonogenic growth.
Hulya Tosun Yildirim +6 more
doaj +1 more source
The role of perineural invasion in predicting survival in patients with primary operable colorectal cancer: a systematic review [PDF]
Perineural invasion is a clear route for cancer cell spread however, the role of nerves in cancer progression is relatively unknown. Recent work would suggest that nerves can actively infiltrate the tumour microenvironment and stimulate cancer cell ...
Going, James +3 more
core +1 more source
Lymphovascular invasion in testicular germ cell tumors: clinicopathological correlates [PDF]
We assessed clinical-pathological correlates of lymphovascular invasion in testicular germ-cell tumors.Archived pathology specimens from 145 patients treated by radical orchiectomy for testicular germ cell tumors at our institution in 1995-2006 were reanalyzed by a dedicated urologic pathologist, and the corresponding medical records were reviewed. The
Yossepowitch, Ofer +5 more
openaire +2 more sources
Survival outcomes and prognostic factors of gastric carcinoma with neuroendocrine differentiation
What's New? Although gastric carcinoma with neuroendocrine differentiation (GCNED) is associated with more aggressive features than conventional GC, its prognosis and survival remain poorly defined. To better understand survival patterns, the authors of the present study examined clinicopathological and prognostic features of GCNED patients following ...
Jinjin Li +7 more
wiley +1 more source
Differentiated Thyroid Cancer in Children and Adolescents: 12-year Experience in a Single Center
INTRODUCTION: Differentiated thyroid cancer (DTC) is the most common pediatric endocrine cancer but studies are scarce. Latest recommendations advocate for an individualized risk-based approach to select patients for additional therapy.
Francisca Marques Puga +6 more
doaj +1 more source
Does prostate acinar adenocarcinoma with Gleason Score 3 + 3 = 6 have the potential to metastasize? [PDF]
Background: There is a worldwide debate involving clinicians, uropathologists as well as patients and their families on whether Gleason score 6 adenocarcinoma should be labelled as cancer.
Briganti, Alberto +7 more
core +1 more source
HIF2A as a prognostic and clinical therapeutic target in ovarian clear cell carcinoma
What's New? Ovarian clear cell carcinoma is highly associated with hypoxia. Hypoxia‐inducible factor 2A (HIF2A) is a key regulator of hypoxic responses, but its role in ovarian clear cell carcinoma remains unclear. This study demonstrated the unfavorable prognostic significance of HIF2A expression in ovarian clear cell carcinoma.
Mengxin Jiang +15 more
wiley +1 more source
Untangling the ATR-CHEK1 network for prognostication, prediction and therapeutic target validation in breast cancer [PDF]
Background: ATR-Chk1 signalling network is critical for genomic stability. ATR-Chk1 may be deregulated in breast cancer and have prognostic, predictive and therapeutic significance.
Abdel-Fatah, TMA +14 more
core +1 more source

