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Surveillance in Lynch Syndrome
Familial Cancer, 2005The major aim of surveillance in Lynch syndrome is to diagnose malignant or premalignant lesions at the asymptomatic stage by regular checkups, particularly in the large bowel. Therefore, screening for colorectal adenomas and carcinomas by regular colonoscopies is the main topic of the present review.
Jukka-Pekka, Mecklin +1 more
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Lynch syndrome: the patients perspective
Familial Cancer, 2013People with Lynch syndrome have a high lifetime risk for the development of colorectal, endometrial and several other types of cancer. Lynch syndrome is caused by germline mutations in genes encoding DNA mismatch repair proteins. In this review, issues that concern Lynch patients are highlighted from the patients' perspective. Both authors are affected
Seppen, Jurgen, Bruzzone, Linda
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Gan to kagaku ryoho. Cancer & chemotherapy, 2019
Lynch syndrome is one of the most common inherited predisposition syndromes which demonstrated autosomal dominant manner and is associated with increased risks of colorectal and endometrial cancer, as well as multiple other cancer types. Lynch syndrome is caused by germline pathogenic variants in any of 4 DNA mismatch repair(MMR)genes MLH1, MSH2, MSH6 ...
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Lynch syndrome is one of the most common inherited predisposition syndromes which demonstrated autosomal dominant manner and is associated with increased risks of colorectal and endometrial cancer, as well as multiple other cancer types. Lynch syndrome is caused by germline pathogenic variants in any of 4 DNA mismatch repair(MMR)genes MLH1, MSH2, MSH6 ...
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Lynch syndrome II and Lynch syndrome I
Journal of the American Academy of Dermatology, 1985openaire +2 more sources
La Clinica terapeutica, 2000
Lynch syndrome is a peculiar disease, accounting for 5% of the total burden of colon cancer. Characteristics of this disease are autosomal dominant transmission, early onset, and frequent right colon localization. Diagnostic criteria, aimed to collaborative studies, are based on these features (so called Amsterdam criteria). Lynch syndrome has specific
P, Fracasso +3 more
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Lynch syndrome is a peculiar disease, accounting for 5% of the total burden of colon cancer. Characteristics of this disease are autosomal dominant transmission, early onset, and frequent right colon localization. Diagnostic criteria, aimed to collaborative studies, are based on these features (so called Amsterdam criteria). Lynch syndrome has specific
P, Fracasso +3 more
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Lynch-like syndrome: Lynch syndrome without known mutation?
Gastroenterología y Hepatología (English Edition), 2021Luisa, Adán-Merino +5 more
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Recent progress in Lynch syndrome and other familial colorectal cancer syndromes
Ca-A Cancer Journal for Clinicians, 2018Patrick M Boland +2 more
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