Results 11 to 20 of about 97,922 (330)
Hyperspectral Imaging Techniques for Lyophilization: Advances in Data‐Driven Modeling Strategies and Applications [PDF]
Advanced ScienceLyophilization, aka freeze drying, is a key process used in the production of biotherapeutic products. The optimization of lyophilization formulations and operations is a slow process that could be accelerated by on‐line analytics.
Huiwen Yu +5 more
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International Journal of Nanomedicine, 2018 Worapol Ngamcherdtrakul,1,2,* Thanapon Sangvanich,1,* Moataz Reda,1 Shenda Gu,1 Daniel Bejan,2 Wassana Yantasee1,2 1Department of Biomedical Engineering, Oregon Health and Science University, Portland, OR, USA; 2Nanomedicine Research Unit, PDX ...
Ngamcherdtrakul W +5 more
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Randomized-field microwave-assisted pharmaceutical lyophilization with closed-loop control [PDF]
Scientific ReportsThe current lyophilization technology for biopharmaceuticals and vaccine products is capital and energy-intensive, largely due to the use of indirect, conductive heat transfer.
Alina A. Alexeenko +18 more
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Lyophilization of Nanoparticles, Does It Really Work? Overview of the Current Status and Challenges
International Journal of Molecular Sciences, 2023 Nanoparticles are being increasingly used as drug delivery systems to enhance the delivery to and uptake by target cells and to reduce off-target toxicity of free drugs.
Matthew S. Gatto, Wided Najahi-Missaoui
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Biomaterials Science, 2023 The limited thermostability and need for ultracold storage conditions are the major drawbacks of the currently used nucleoside-modified lipid nanoparticle (LNP)-formulated messenger RNA (mRNA) vaccines, which hamper the distribution of these vaccines in ...
Alexander Lamoot +7 more
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Lyophilization Based Isolation of Exosomes
International Journal of Molecular Sciences, 2023 Exosomes are nanoscale extracellular vesicles which regulate intercellular communication. They have great potential for application in nanomedicine. However, techniques for their isolation are limited by requirements for advanced instruments and costly ...
Rida-e-Maria Qazi +7 more
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Brazilian Journal of Pharmaceutical Sciences, 2023 The purpose of the present study was to develop stable lyophilized formulation of peginterferon alfa-2b which is acquiescent to the short lyophilization process.
Patel Chintan, Patel Gayatri
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Annals of Microbiology, 2022 Purpose Uridine diphosphate glucose pyrophosphorylase (UGPase) plays an important role in glucose metabolism, catalyzing the reversible formation and decomposition of UDP-glucose (UDPG).
Chaoran Xia +6 more
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Limited influence of marine sediment lyophilization on prokaryotic community structure assessed via amplicon sequencing: an example from environmentally contrasted sediment layers in Toulon harbor (France) [PDF]
PeerJ, 2021 Sediment lyophilization is a common process that allows for long-term conservation and sharing of marine sediments for multiple downstream analyses. Although it is often used for geochemical studies, the effects of lyophilization on prokaryotic taxonomic
Benjamin Misson +2 more
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Lyophilization of Nanocapsules: Instability Sources, Formulation and Process Parameters
Pharmaceutics, 2021 Polymeric nanocapsules have gained more and more interest in the medical sciences. Their core-shell structure offers numerous advantages, especially regarding their use as drug delivery systems.
G. Degobert, Dunya Aydin
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