Results 131 to 140 of about 880 (178)
Beyond transplants: current and future therapeutic potential of amniotic membrane extract (AME) in ophthalmology. [PDF]
Regen MedKorkmaz I +3 more
europepmc +1 more source
Ritonavir-Loaded PEG-<i>b</i>-PCL Polymeric Micelles: Reduced Excipient Requirements and Comparable Oral Pharmacokinetics in Rats. [PDF]
Pharmaceuticals (Basel)Lee E +5 more
europepmc +1 more source
International Journal of Pharmaceutics, 2015 The purpose of this work was to evaluate the influence of the co-encapsulation of lyoprotectants with insulin into PLGA nanoparticles, on the stability of the protein and nanoparticles upon lyophilization.
Bruno Sarmento +2 more
exaly +2 more sources
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Food Chemistry, 2023
Nanoliposome is a promising delivery system, whereas its commercial application is limited by the structural instability, cargo leakage and particles aggregation during the processing such as freeze-drying. In this study, the effect of four oligosaccharides, fructo-oligosaccharides, lactose, inulin and sucrose (control), on the physicochemical ...
Lifang Feng, Xiankang Xu, Weilin Liu
exaly +3 more sources
Nanoliposome is a promising delivery system, whereas its commercial application is limited by the structural instability, cargo leakage and particles aggregation during the processing such as freeze-drying. In this study, the effect of four oligosaccharides, fructo-oligosaccharides, lactose, inulin and sucrose (control), on the physicochemical ...
Lifang Feng, Xiankang Xu, Weilin Liu
exaly +3 more sources
Dramatic enhancement of enzymatic activity in organic solvents by lyoprotectants
Biotechnology and Bioengineering, 1993AbstractWhen seven different hydrolytic enzymes (four proteases and three lipases) were lyophilized from aqueous solution containing a ligand, N‐Ac‐L‐Phe‐NH2, their catalytic activity in anhydrous solvents was far greater (one to two orders of magnitude) than that of the enzymes lyophilized without the ligand.
A M Klibanov, Alexander M Klibanov
exaly +3 more sources
Maltodextrins as Lyoprotectants in the Lyophilization of a Model Protein, LDH
Pharmaceutical Research, 1996Maltodextrins, partially hydrolysed starches, were evaluated as potential lyoprotectants and the effect of combinations of maltodextrins and PEG 8000 on the protection of lactate dehydrogenase (LDH) was examined.LDH activity assays were performed immediately before freezing and after reconstruction.
Jean Paul Remon, Jean-Paul Remon
exaly +3 more sources
Lyoprotected Nanosphere Formulations for Paclitaxel Controlled Delivery
Journal of Nanoscience and Nanotechnology, 2006The preparation and technological characterization of nanosphere formulations (NS) containing the anticancer drug paclitaxel (PTX) are reported. Poly(lactide) (PLA) and poly(lactide-co-glycolide) (PLGA) nanospheres (NS) were prepared by a solvent displacement method.
MUSUMECI, TERESA +5 more
openaire +2 more sources
Reversible self-polymerizing high Tg lyoprotectants
Cryobiology, 2002One mode of action of protectants in the storage of biological materials is by promoting the formation of a vitrified state on cooling or drying. In the case of preservation by drying, the glassy material comprises a low water content mixture of protectant and organic material.
D R, MacFarlane, J, Pringle, G, Annat
openaire +2 more sources