Results 151 to 160 of about 880 (178)
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Inulin like lyoprotectant of bovine plasma proteins concentrated by ultrafiltration
Food Research International, 2010The growth of world demand for protein-enriched products generates a great interest in the search of new protein sources of higher nutritional value and, therefore, in the use of cutting edge technologies to achieve that goal. In this work, technologies of ultrafiltration and freeze-drying to process and obtain a protein concentrate from bovine plasma ...
Laura T. Rodríguez Furlán +2 more
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Discriminating between dispersion and lyoprotection effects in biocatalysis in organic media
Canadian Journal of Chemistry, 2002The increment of activity and solubility in 1,4-dioxane of lipase B from Candida antarctica, lipase from Pseudomonas cepacia, and subtilisin, were investigated as a function of the methoxypoly(ethylene glycol)protein (PEGprotein) ratio employed during lyophilization.
Secundo F, Carrea G, Veronese FM
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Hemoglobin-based high-throughput assessment of lyoprotectant efficacy
CryobiologyBiologics, including vaccines, therapeutic proteins, blood products, and cell therapies, are susceptible to degradation during drying and therefore require the incorporation of protective additives (lyoprotectants) into the processing formulation to maintain their desired biological activities after reconstitution.
Charles A. Elder +7 more
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Stability of Freeze-Dried Ovalbumin-Alginate Microspheres with Different Lyoprotectants
Research Journal of Pharmacy and Technology, 2016Stability and denaturation has been widely known as main disadvantages in the oral delivery of drug or protein. The aim of this research was to investigate stability of ovalbumin-alginate microspheres during production and storage. Ovalbumin-alginate microspheres were prepared using sodium alginate polymer, CaCl2 cross linker and different ...
Dewi Melani Hariyadi +2 more
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Journal of Pharmaceutical Sciences, 2017
The concentration of maximally freeze-concentrated solutions [Formula: see text] and the corresponding glass transition temperature [Formula: see text] and ante-melting temperature [Formula: see text] of lyoprotectant solutions, are critical parameters for developing lyophilization process.
Zhang Shaozhi
exaly +3 more sources
The concentration of maximally freeze-concentrated solutions [Formula: see text] and the corresponding glass transition temperature [Formula: see text] and ante-melting temperature [Formula: see text] of lyoprotectant solutions, are critical parameters for developing lyophilization process.
Zhang Shaozhi
exaly +3 more sources
Lyoprotection de l'hémoglobine par le N-acétyl tryptophane
Revue Francaise de Transfusion et Immuno-hématologie, 1982Resume Des determinations de taux de methemoglobine, de differentes capacites de transport d'oxygene et de l'affinite pour ce ligand ont ete effectuees sur des hemoglobines lyophilisees en l'absence ou en presence de N-acetyl tryptophane et/ou d'α-D glucose.
J SAINTBLANCARD, P RAMBOURG, D DOUCET
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Sweet corn phytoglycogen dendrimers as a lyoprotectant for dry‐state protein storage
Journal of Biomedical Materials Research Part AAbstractProtein biotherapeutics typically require expensive cold‐chain storage to maintain their fold and function. Packaging proteins in the dry state via lyophilization can reduce these cold‐chain requirements. However, formulating proteins for lyophilization often requires extensive optimization of excipients that both maintain the protein folded ...
Junha Park +9 more
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Long term stability of freeze-dried, lyoprotected doxorubicin liposomes
European Journal of Pharmaceutics and Biopharmaceutics, 1997Abstract The aim of the present study was to determine which parameters influence the long term stability of freeze-dried doxorubicin (DXR) liposomes. The DXR content, DXR retention and average vesicle size of the rehydrated liposomes were examined as a function of storage temperature, lyoprotectant (sucrose, maltose, lactose and trehalose), residual
van Winden, E.C.A., Crommelin, D.J.A.
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Cryobiology
Nowadays the significant role of biobanks in medical, diagnostic, industrial, and environmental research is well known. Bacterial biobanks could be used as a good resource for designing new treatments, biomedical and industrial researches, and laboratory diagnostics.
Masoud Alebouyeh +2 more
exaly +3 more sources
Nowadays the significant role of biobanks in medical, diagnostic, industrial, and environmental research is well known. Bacterial biobanks could be used as a good resource for designing new treatments, biomedical and industrial researches, and laboratory diagnostics.
Masoud Alebouyeh +2 more
exaly +3 more sources
Molecular Pharmaceutics
Many cell-based therapies, such as live biotherapeutic products (LBPs), require preservation of cell viability during manufacturing, transportation, and storage before being delivered to patients. Although lyophilization is a common strategy to improve storage stability, it can compromise cell viability, thus reducing therapeutic efficacy.
Haixi Cui +6 more
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Many cell-based therapies, such as live biotherapeutic products (LBPs), require preservation of cell viability during manufacturing, transportation, and storage before being delivered to patients. Although lyophilization is a common strategy to improve storage stability, it can compromise cell viability, thus reducing therapeutic efficacy.
Haixi Cui +6 more
openaire +2 more sources