Results 161 to 170 of about 880 (178)

Cryoprotectants and Lyoprotectants: A Complete Assessment of Mechanism, Toxicity, and Applications for Pharmaceuticals

Current Nanomedicine
Introduction:: Cryopreservation has become a critical technique across various domains, including clinical care, biotechnology, and plant and animal biology. It enables the longterm storage of cells, tissues, and biological products at ultra-low temperatures, preserving their viability and functionality ...
Prince Piyush, Vijay Agarwal, Munendra Mohan Varshney   +2 more
openaire   +1 more source

Physicochemical and structural insights into lyophilized mRNA-LNP from lyoprotectant and buffer screenings

Journal of Controlled Release
The surge in RNA therapeutics has revolutionized treatments for infectious diseases like COVID-19 and shows the potential to expand into other therapeutic areas. However, the typical requirement for ultra-cold storage of mRNA-LNP formulations poses significant logistical challenges for global distribution.
Yuchen, Fan, Diamanda, Rigas, Lee Joon, Kim, Feng-Peng, Chang, Nanzhi, Zang, Kristina, McKee, Christopher C, Kemball, Zhixin, Yu, Pascal, Winkler, Wan-Chih, Su, Pierce, Jessen, Greg L, Hura, Tao, Chen, Stefan G, Koenig, Karthik, Nagapudi, Dennis, Leung, Chun-Wan, Yen   +16 more
openaire   +2 more sources

Influence of type and concentration of lyoprotectants, storage temperature and storage duration on cell viability and antibacterial activity of freeze-dried lactic acid bacterium, Lactococcus lactis Gh1

Drying Technology, 2022
Roslina Jawan, Sahar Abbasiliasi, Arbakariya B Ariff   +2 more
exaly  

Effects of Lyoprotectants on Long-Term Stability and Transfection Efficacy of Lyophilized Poly(Lactide-Co-Glycolide)-Graft-Polyethylenimine/Plasmid DNA Polyplexes

Nanomedicine, 2021
Jeoung Soo Lee, Joshua Woo
exaly  

Optimization of the synthesis process of β-galactosidase/carboxymethylchitosan-silica biocatalyst powders, stabilized with lyoprotectants for potential dietary applications

Journal of Food Process Engineering, 2023
Mónica Mesa, Yuly Nataly Franco Tobón
exaly  

Fabrication and characterization of walnut peptides-loaded proliposomes with three lyoprotectants: Environmental stabilities and antioxidant/antibacterial activities

Food Chemistry, 2022
Wenting Tang, Qingjie Sun, Yue Sun
exaly  

METHODS FOR CRYOPROTECTION AND LYOPROTECTION OF CELLS

2022
KARDORFF MARKUS, JERE DHANANJAY
openaire   +1 more source

Lyoprotectant compositions and uses thereof

2023
BOUHADIR SPENCER, MIGUEL JACOB J
openaire   +1 more source

Lyoprotectants for improved freeze-drying survival of environmental bacterial isolates

XVI. SUSRET MLADIH KEMIJSKIH INŽENJERA - KNJIGA SAŽETAKA
Preserving environmental bacteria is essential for understanding ecosystem processes, monitoring environmental change, and maintaining cultures used in ecological and biotechnological research. However, long-term storage of microorganisms remains challenging, especially for strains that are difficult to cultivate or originate from fluctuating natural ...
Vuković Domanovac, Marija, Sudar, Martina, Šabić Runjavec, Monika   +2 more
openaire  

Effects of freeze drying in complex lyoprotectants on the survival, and membrane fatty acid composition of L1 and L2

Cryobiology, 2022
Jingyi Wu
exaly