Results 71 to 80 of about 8,921 (227)

Substance use in the club scene of Rome : a pilot study [PDF]

, 2014
Date of Acceptance: 28/08/2014 Copyright © 2014 Alessandro Emiliano Vento et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium ...
Acciavatti, Tiziano, Bonifaci, Ludovica, Carrus, Dario, Chillemi, Eleonora, Cinosi, Eduardo, Corazza, Ornella, di Giannantonio, Massimo, Lupi, Matteo, Martinotti, Giovanni, Santacroce, Rita, Schifano, Fabrizio, Vento, Alessandro   +11 more
core   +4 more sources

Psychedelics, entactogens and psychoplastogens for depression and related disorders

British Journal of Pharmacology, EarlyView.
Currently, the most actively investigated rapidly acting antidepressants, anxiolytics and/or anti PTSD agents, include psychedelics e.g. psilocybin, LSD, N,N‐dimethyltryptamine, ayahuasca; non‐hallucinogenic entactogens, e.g. MDMA; psychoplastogens which rapidly promote neuroplasticity, e.g.
Daniel Hoyer
wiley   +1 more source

LSD Administered as a Single Dose Reduces Alcohol Consumption in C57BL/6J Mice

Frontiers in Pharmacology, 2018
There is a substantive clinical literature on classical hallucinogens, most commonly lysergic acid diethylamide (LSD) for the treatment of alcohol use disorder.
Kenneth Alper, Kenneth Alper, Bin Dong, Relish Shah, Henry Sershen, Henry Sershen, K. Yaragudri Vinod, K. Yaragudri Vinod, K. Yaragudri Vinod   +8 more
doaj   +1 more source

Polypharmacy among anabolic-androgenic steroid users: A descriptive metasynthesis [PDF]

, 2015
Background: As far as we are aware, no previous systematic review and synthesis of the qualitative/descriptive literature on polypharmacy in anabolic-androgenic steroid(s) (AAS) users has been published. Method: We systematically reviewed and synthesized
AJ Gruber, AJ Gruber, AJ Gruber, AJ McBride, AJ Viera, Astrid Bjørnebekk, B Hegazy, B Larance, C Ahlgrim, C Wilson-Fearon, Cecilie Schou Andreassen, CN Schäfer, CS Cornford, D Hoff, D Moher, D Moher, D Sagoe, D Sagoe, DA Malone Jr, DL Katz, Dominic Sagoe, E Chahla, E Pappa, F Klötz, G Kanayama, G Kanayama, G Kanayama, G McKillop, GS Goldfield, H Angoorani, H Geyer, HB Moss, HB Moss, HG Pope Jr, HG Pope Jr, IBM Corp, J Bilard, JA Smith, JD Wines, Jim McVeigh, JR Hoffman, K Skårberg, K Skårberg, K Skårberg, KA Clauson, L Degenhardt, L Lundholm, LJ Silvester, M Chandler, M Dunn, M Evans-Brown, Marie-Stella Essilfie, MJ Evans-Brown, N Gårevik, P Korkia, P Korkia, P Lenehan, PJ Fudala, PJ Perry, PJ Perry, R Davies, R Peters, R Shaw, RH Strauss, RP Kusserow, RT Dawson, S Darke, SM Filiault, Ståle Pallesen, T Dodge, T Hildebrandt, TA Pagonis, V Tallon, VD Hope, W Rashid   +74 more
core   +2 more sources

Evidence that 5‐HT2A receptor signalling efficacy and not biased agonism differentiates serotonergic psychedelic from non‐psychedelic drugs

British Journal of Pharmacology, EarlyView.
Background and Purpose Serotonergic psychedelic drugs are under investigation as therapies for various psychiatric disorders, including major depression. Although serotonergic psychedelic drugs are 5‐HT2A receptor agonists, some such agonists are not psychedelic, potentially due to differences in 5‐HT2A receptor ligand bias or signalling efficacy. Here,
Aurelija Ippolito, Sridhar Vasudevan, Shaun Hurley, Gary Gilmour, Frederick Westhorpe, Grant Churchill, Trevor Sharp   +6 more
wiley   +1 more source

Treatment of neuropathic pain with repeated low-dose MDMA: a case report

Frontiers in Psychiatry
A 64-year-old male patient who suffered from traumatic life experiences and neuropathic pain after oncological chemotherapy was treated with medium to high doses of lysergic acid diethylamide (LSD) and high doses and microdoses of ...
Peter Gasser, Matthias E. Liechti, Friederike Holze   +2 more
doaj   +1 more source

A mood disorder episode with an onset under chronic cannabis consumption and accompanied with psychotic features immediately after N, N-Dimethyltryptamine (DMT) use: a case report [PDF]

Düşünen Adam Psikiyatri ve Nörolojik Bilimler Dergisi, 2011
, N-dimethyltryptamine (DMT) is a serotonin agonist hallucinogen, similar to lysergic acid diethylamide (LSD). Syntetic production of DMT as well as extraction from several plants of South American flora is possible.
Güliz Özgen, İlker Küçükparlak, Gökhan Umut, Ahmet Türkcan   +3 more
doaj  

Psychedelics Promote Structural and Functional Neural Plasticity. [PDF]

, 2018
Atrophy of neurons in the prefrontal cortex (PFC) plays a key role in the pathophysiology of depression and related disorders. The ability to promote both structural and functional plasticity in the PFC has been hypothesized to underlie the fast ...
Barragan, Eden V, Burbach, Kyle F, Cameron, Lindsay P, Dennis, Megan Y, Duim, Whitney C, Gray, John A, Greb, Alexandra C, Ly, Calvin, McAllister, A Kimberley, Olson, David E, Ori-McKenney, Kassandra M, Paddy, Michael R, Soltanzadeh Zarandi, Sina, Sood, Alexander, Wilson, Paige C, Wong, Jonathan M   +15 more
core   +2 more sources

Are we hallucinating or can psychedelic drugs modulate the immune system to control inflammation?

British Journal of Pharmacology, EarlyView.
Psychedelic drugs that activate 5‐HT2A receptors have been long used for cultural, medicinal and recreational purposes. Interest in psychedelics for treating psychiatric disorders has resurged recently and is well documented; less well recognised are their anti‐inflammatory properties. Growing evidence now demonstrates that psychedelics modulate immune
Omar Qureshi, Jamie Cowley, Ashley Pegg, Alison J. Cooper, John Gordon, Catherine A. Brady, Antonio Belli, Sam Butterworth, Rachel Upthegrove, Nick Andrews, Nicholas M. Barnes   +10 more
wiley   +1 more source

Psychedelics as pharmacotherapeutics for substance use disorders: A scoping review on clinical trials and perspectives on underlying neurobiology

British Journal of Pharmacology, EarlyView.
Theorized mechanism of dopamine homeostasis restoration in the nucleus accumbens core induced by a psychedelic intervention. Abstract Psychedelics have garnered great attention in recent years as treatments for major depressive disorder (MDD) and treatment‐resistant depression because of their ability to alter consciousness and afflicted cognitive ...
Lucas Wittenkeller, Gary Gudelsky, T. John Winhusen, Davide Amato   +3 more
wiley   +1 more source