Results 101 to 110 of about 996,868 (382)
Targeting euchromatic histone lysine methyltransferases sensitizes colorectal cancer to histone deacetylase inhibitors [PDF]
, 2022 L Bamberg +15 more
openalex +1 more source
Chemical and Biochemical Perspectives of Protein Lysine Methylation.
Chemical Reviews, 2018 Protein lysine methylation is a distinct posttranslational modification that causes minimal changes in the size and electrostatic status of lysine residues.
M. Luo
semanticscholar +1 more source
Molecular Oncology, EarlyView.Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié +16 more
wiley +1 more source
Survivin and Aurora Kinase A control cell fate decisions during mitosis
Molecular Oncology, EarlyView.Aurora A interacts with survivin during mitosis and regulates its centromeric role. Loss of Aurora A activity mislocalises survivin, the CPC and BubR1, leading to disruption of the spindle checkpoint and triggering premature mitotic exit, which we refer to as ‘mitotic slippage’.
Hana Abdelkabir +2 more
wiley +1 more source
The effect of phase-feeding on the growth performance, carcass characteristics and nitrogen balance of growing and finishing pigs. [PDF]
, 2007 peer-reviewedA completely randomised design experiment was conducted to determine if grouphoused grower-finisher pigs (43.9 to 95 kg) show differences in performance and nitrogen utilisation when provided with a single high lysine diet (11 g/kg) or with ...
Garry, B.P. +2 more
core
A procedure to evaluate the efficiency of utilization of dietary amino acid for poultry
Acta Scientiarum: Animal Sciences, 2014 The aim of this study was to develop a procedure based on Gompertz function to determine the efficiency of utilization of amino acid. The procedure was applied to determine the efficiency of utilization of dietary lysine, methionine+cystine and threonine
Edney Pereira da Silva +5 more
doaj +1 more source
Chemo- and Regioselective Lysine Modification on Native Proteins
Journal of the American Chemical Society, 2018 Site-selective chemical conjugation of synthetic molecules to proteins expands their functional and therapeutic capacity. Current protein modification methods, based on synthetic and biochemical technologies, can achieve site selectivity, but these ...
M. Matos +13 more
semanticscholar +1 more source
Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA
Molecular Oncology, EarlyView.Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson +2 more
wiley +1 more source
Immobilization of Motile Bacterial Cells via Dip-pen Nanolithography [PDF]
, 2010 A strategy to bind bacterial cells to surfaces in a directed fashion via dip-pen nanolithography (DPN) is presented. Cellular attachment to pre-designed DPN generated microarrays was found to be dependent on the shape and size of the surface feature ...
Holz, Richard C. +2 more
core +2 more sources
European Journal of Entomology, 2002 A series of experiments were conducted to compare the susceptibility of P. regina larvae reared in isolation or in groups to the effects of diet-borne metabolic inhibitors: chlorogenic acid (CGA) and mimosine.
Paul W.C. GREEN +2 more
doaj +1 more source