Results 121 to 130 of about 609,507 (300)

Proline cis-trans isomerization is influenced by local lysine acetylation-deacetylation

open access: yes, 2014
Acetylation of lysine residues has several characterised functions in chromatin. These include neutralization of the lysine’s positive charge to directly influence histone tail-DNA/internucleosomal interactions or indirect effects via bromodomain ...
Jane Mellor, Françoise S. Howe
core   +1 more source

Sulfation‐Tunable Peptide‐Glycosaminoglycan Hydrogels for Hematopoietic Stem and Progenitor Cell Expansion

open access: yesAdvanced Functional Materials, EarlyView.
Co‐assembly of rationally designed glycosaminoglycan‐binding peptides with sulfated glycosaminoglycans yields supramolecular hydrogels with tunable mechanics and matrix‐mediated cytokine retention. The glycosaminoglycans thereby act as cofactors, driving a coil‐to‐β‐sheet transition that triggers gelation.
Shirel Veretnik   +8 more
wiley   +1 more source

Lysine-Tryptophan-Crosslinked Peptides Produced by Radical SAM Enzymes in Pathogenic Streptococci

open access: yes, 2017
Macrocycles represent a common structural framework in many naturally occurring peptides. Several strategies exist for macrocyclization, and the enzymes that incorporate them are of great interest, as they enhance our repertoire for creating complex ...
Mohammad R. Seyedsayamdost (129142)   +1 more
core   +1 more source

Bioinspired Co‐Assembly Enables Multiscale Architected Hydrogels for 3D Printing With Integrated Antibacterial and Bioactive Functions

open access: yesAdvanced Functional Materials, EarlyView.
A multicomponent supramolecular hydrogel integrating cell‐adhesive and antibacterial peptides within an alginate‐cellulose nanofibril matrix is developed. Peptide co‐assembly simultaneously strengthens the hydrogel network, improves extrusion printability, and imparts cell‐adhesive and antibacterial functions, offering a versatile platform for ...
Mor Tsuriano‐Zernichov   +4 more
wiley   +1 more source

Self‐Assembled Lipids as Soft Dielectrics

open access: yesAdvanced Functional Materials, EarlyView.
Self‐assembled lipid bilayers serve as soft dielectric materials for ultrathin electronics. Using liquid‐metal parallel‐plate junctions, the capacitance and dielectric breakdown of dehydrated lipid films are characterized. Dielectric behavior is controlled by lipid molecular structure, cholesterol content, and assembly conditions, providing molecular ...
Hao Yang   +4 more
wiley   +1 more source

Additional file 1: of Improved safety and efficacy of 213Bi-DOTATATE-targeted alpha therapy of somatostatin receptor-expressing neuroendocrine tumors in mice pre-treated with l-lysine

open access: yes, 2017
Improved safety and efficacy of 213Bi-DOTATATE targeted alpha therapy of somatostatin receptor-expressing neuroendrocrine tumors in mice pre-treated with L-lysine.
Mehran Makvandi (3766129)   +9 more
core   +1 more source

3D Bioprinted Glioblastoma Multiforme Models: How the Extracellular Matrix Glycosignature Influences Drug Response

open access: yesAdvanced Functional Materials, EarlyView.
Aberrant glycosylation in the glioblastoma tumor microenvironment drives therapeutic resistance. Here, a 3D bioprinted model was engineered by incorporating α‐NeuNAc‐(2→3)‐β‐D‐Gal‐ and chondroitin sulfate. Combined multiplex immunofluorescence and synchrotron‐based nanoCT analysis revealed that glycan‐matrix interactions dictate specific drug‐escape ...
Francesca Cadamuro   +25 more
wiley   +1 more source

ARCHER DANIELS MIDLAND:PRICE FIXER TO THE WORLD (Third Edition) [PDF]

open access: yes
Both market structure and corporate practices of Archer Daniels Midland fostered the implementation of the largest price-fixing conspiracies seen in modern times. The overcharges imposed on U.S.
John M. Connor
core  

The Impact of Thermal Treatments up to 140 °C on Amino Acid Digestibility of Fish Meal in Rainbow Trout (Oncorhynchus mykiss)

open access: yesFishes
Fish meal (FM) is an essential ingredient in fish feeds, but the thermal treatments used during its production might affect its nutrient availability. Therefore, an in vivo digestibility trial was conducted with three different thermal treated FM, at no ...
Pedro Henrique Sessegolo Ferzola   +3 more
doaj   +1 more source

Engineered Nanotopography to Modulate Growth and Signaling of Neuronal Networks

open access: yesAdvanced Functional Materials, EarlyView.
This study examines the interaction between neurons and nanoscale topographies on engineered substrates. Neurons cultured on nanowires, nanopillars and nanoneedles exhibit enhanced neurite outgrowth, form more organized neuronal circuits, and display improved synaptic connectivity, compared to flat substrates.
Hao Nguyen Tran   +8 more
wiley   +1 more source

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