Results 261 to 270 of about 898,492 (409)

α‐Synuclein Pathology Spreads in a Midbrain–Hindbrain Assembloid Model

Advanced Science, EarlyView.
A novel midbrain–hindbrain assembloid model demonstrates the spread of α‐synuclein pathology, a hallmark of Parkinson's disease, mimicking Braak's hypothesis. This model reveals how pathology propagates from the hindbrain to the midbrain, inducing synaptic changes and early signs of neuronal vulnerability. It offers an innovative platform for exploring
Gemma Gomez‐Giro, Daniela Frangenberg, Daniela Vega, Alise Zagare, Kyriaki Barmpa, Paul M. A. Antony, Graham Robertson, Rahman Sabahi‐Kaviani, Kristian Haendler, Nathalie Kruse, Florentia Papastefanaki, Rebecca Matsas, Malte Spielmann, Regina Luttge, Jens C. Schwamborn   +14 more
wiley   +1 more source

Preparation of Hydroxylysine-epsilon-14C and Lysine-epsilon-14C. [PDF]

, 1953
Sven Lindstedt, Kurt Rubinstein, Kai Jensen, E. Schønfeldt, Inger Steensgaard, Th. Rosenberg   +5 more
openalex   +1 more source

Evaluation of protein intake and protein quality in New Zealand vegans. [PDF]

PLoS One
Soh BXP, Vignes M, Smith NW, von Hurst PR, McNabb WC.   +4 more
europepmc   +1 more source

ZMYND8 Reads H3K36me2 to Activate CEBPE Transcription and Suppress Multiple Myeloma Progression through the Inhibition of Adaptive UPR Pathways

Advanced Science, EarlyView.
Zinc‐finger MYND‐type‐containing 8 (ZMYND8) activates the transcription of CCAAT/enhancer‐binding protein epsilon by recognizing dimethylation of lysine 36 in histone H3 through its Pro‐Trp‐Trp‐Pro domain, thereby inhibiting adaptive unfolded protein response pathways to suppress the proliferation and invasion of multiple myeloma (MM) cells ...
Jiaxuan Xu, Xiaoqing Dong, Yue Peng, Jie Yan, Peipei Xu, Feiyu Li, Suwen Zhang, Lanxin Chen, Xingjun Meng, Kangning Wang, Mengying Xing, Wenyang Li, David C. S. Huang, Quan Zhao, Bing Chen   +14 more
wiley   +1 more source

Effect of Lysine-Deficiency on Hematopoiesis in the Chick, Including Observations on Folic Acid Deficiency

, 1957
George J. Klain, D.C. Hill, H.D. Branion
openalex   +1 more source

Proximal cysteine residues in proteins promote N^ε-carboxyalkylation of lysine residues by α-dicarbonyl compounds. [PDF]

J Biol Chem
Panja S, Rankenberg J, Michel C, Cooksley G, Glomb MA, Nagaraj RH.   +5 more
europepmc   +1 more source

In‐Depth Cell‐Type‐Specific Proteome Landscape of the Brain from Human Amyloid‐β Overexpression Mouse Model

Advanced Science, EarlyView.
In situ Cell‐type‐specific proteome Analysis using antibody‐mediated Biotinylation (iCAB) is a method that directly targets and analyzes proteins in specific cell types within tissue. Applied to 5xFAD mice, iCAB identifies ≈8000 cell‐type‐specific proteins, revealing unique pathways in neurons, astrocytes, and microglia.
Taekyung Ryu, Seok‐Young Kim, Thujitha Thuraisamy, Jisu Shin, Yura Jang, Tae‐In Kam, Chan Hyun Na   +6 more
wiley   +1 more source

THE PREPARATION OF LYSINE FROM PROTEIN HYDROLYSATES

, 1951
E. V. McCollum, Agatha A. Rider
openalex   +1 more source

Insights in wound healing properties of water-soluble composition of dihydroquercetin and L-lysine. [PDF]

J Pharm Pharm Sci
Svotin AA, Taldaev A, Nikitin ID, Korochkina MD, Terekhov RP, Selivanova IA.   +5 more
europepmc   +1 more source

Nanotherapy for Neural Retinal Regeneration

Advanced Science, EarlyView.
Nanotechnology enhances ophthalmic treatments by improving drug delivery and regenerating ocular tissues, combating vision loss from retinal diseases through innovative nano‐systems. This review outlines ocular anatomy, pathology, immune microenvironment, and barriers, detailing nanocarrier characteristics, classification, and preparation methods, and ...
Chuyao Yu, Li Dong, Yujia Lv, Xuhan Shi, Ruiheng Zhang, Wenda Zhou, Haotian Wu, Heyan Li, Yitong Li, Zhou Li, Dan Luo, Wen‐Bin Wei   +11 more
wiley   +1 more source