Results 71 to 80 of about 787,190 (346)
Bioavailability of lysine from hydroxymethyl lysine
Kansas Agricultural Experiment Station Research Reports, 2010 Twelve mature sheep were used as a ruminant model to estimate the bioavailability of lysine in hydroxymethyl lysine (HML) compared with a commercial product of rumen-protected lysine (RPL; LysiPEARL, Kemin Industries, Inc.) with known availability. The sheep were fed a diet with a forage to concentrate ratio similar to that of dairy diets.
E.A. Elwakeel +3 more
openaire +2 more sources
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Cell, 2011 Summary Using an integrated approach, we here report the identification of 67 novel histone marks, a discovery that increases the current number of known histone marks by about 70%. We verified one of the newly-identified marks, lysine crotonylation (Kcr)
Min-Jia Tan +17 more
semanticscholar +1 more source
Suppressors of lysine codons may be misacylated lysine tRNAs [PDF]
Journal of Bacteriology, 1983 We describe a novel class of missense suppressors that read the codons for lysine at two positions (211 and 234) in the trpA polypeptide of Escherichia coli. The suppressor mutations are highly linked to lysT, a gene for lysine tRNA. The results suggest that the suppressors are misacylated lysine tRNAs that carry glycine or alanine.
E J, Murgola, F T, Pagel
openaire +2 more sources
Acetylation site specificities of lysine deacetylase inhibitors in human cells [PDF]
, 2015 This work was supported by the Hallas Møller Investigator grant from the Novo Nordisk Foundation to C.C. S.A.W. and P.B. were supported by individual postdoctoral grants from the Danish Research Council (FSS: 10-085134, FSS: 12-12610). C.C.
Sebastian A Wagner +83 more
core +1 more source
Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
Animal, 2013 The objectives of this study were to compare the in situ ruminal degradation of CP and amino acids (AAs) of dried distillers’ grains with solubles (DDGS), and to estimate intestinal digestibility (ID) of undegradable crude protein (UDP) with the in vitro
E. Westreicher-Kristen +2 more
doaj +1 more source
Frontiers in Bioengineering and Biotechnology, 2021 Fructose utilization in Corynebacterium glutamicum starts with its uptake and concomitant phosphorylation via the phosphotransferase system (PTS) to yield intracellular fructose 1-phosphate, which enters glycolysis upon ATP-dependent phosphorylation to ...
Irene Krahn +11 more
doaj +1 more source
Metabolic Regulation of Gene Expression by Histone Lysine β-hydroxybutyrylation
Molecules and Cells, 2016 SUMMARY Here we report the identification and verification of a β-hydroxybutyrate-derived protein modification, lysine β-hydroxybutyrylation (Kbhb), as a new type of histone mark.
Zhongyu Xie +26 more
semanticscholar +1 more source
Translophagy—A potential link between autophagy impairment and translational errors
FEBS Letters, EarlyView.Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk +11 more
wiley +1 more source