Crystalline amino acids (AAs) exhibit high nutritional values when supplemented AA-deficient diets. However, the AAs in crystalline form in the diet are absorbed quickly than protein-bound AAs, which may take an effect on AA utilization efficiency.
Mingfa Sun +5 more
doaj +1 more source
Lysine-Dendrimer, a New Non-Aggressive Solution to Rebalance the Microbiota of Acne-Prone Skin
Acne is a chronic inflammatory skin disease that affects the quality of life of patients. Several treatments exist for acne, but their effectiveness tends to decrease over time due to increasing resistance to treatment and associated side effects.
Julie Leignadier +6 more
doaj +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Impact of histone H4 lysine 20 methylation on 53BP1 responses to chromosomal double strand breaks. [PDF]
Recruitment of 53BP1 to chromatin flanking double strand breaks (DSBs) requires γH2AX/MDC1/RNF8-dependent ubiquitination of chromatin and interaction of 53BP1 with histone H4 methylated on lysine 20 (H4K20me). Several histone methyltransferases have been
Guan, Yinghua +26 more
core +2 more sources
Application of different sterilising modes and the effects on processed cheese quality
The aim of the present work is to evaluate the impacts of four different sterilising modes (110°C 100 min, 115°C 32 min, 120°C 10 min, and 125°C 3.2 min - with a constant lethal effect on microorganisms) on some chemical (pH, total and bio-available ...
Zuzana Lazárková +5 more
doaj +1 more source
Summary: Previous research has shown that feeding high amino acid density (AAD) diets or increased AME improved broiler performance, though the relationship between AAD and AME on performance needs to be further explored. Therefore, the objective of this
R.A. Hirai +5 more
doaj +1 more source
Epigenetic reprogramming of lineage switching in cancer
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı +4 more
wiley +1 more source
Analysis of Jmjd6 cellular localization and testing for its involvement in histone demethylation. [PDF]
Methylation of residues in histone tails is part of a network that regulates gene expression. JmjC domain containing proteins catalyze the oxidative removal of methyl groups on histone lysine residues.
Erck, C +51 more
core +2 more sources
PATHOLOGICAL EFFECTS OF FEEDING COTTONSEED MEAL WITH AND WITHOUT LYSINE IN MALE JAPANESE QUAILS (COTURNIX JAPONICA) [PDF]
A total of 84 male Japanese quails (Coturnix japonica) of 40 days of age were randomly divided into seven groups (A to G) with 12 birds in each group. A corn and soybean meal based feed having 25% proteins was offered to group A (control) as a basal feed.
M. ILYAS, M. K. SALEEMI, F. MAHMOOD AND M. Z. KHAN
doaj
Maillard reaction products from glucose-methionine mixtures affect iron utilization in rats
The influence of Maillard reaction products from glucose-methionine on iron bioavailability was investigated, and compared with those from glucose-lysine (both 40% moisture, 150°C, 90 min).
C. Delgado-Andrade +2 more
doaj +1 more source

