Results 71 to 80 of about 438,961 (309)
Nature PlantsHistone acetylation is a predominant active chromatin mark deposited by histone acetyltransferases (HATs) that transfer the acetyl group from acetyl coenzyme A (acetyl-CoA) to lysine ε-amino groups in histones.
Yue Yu +4 more
semanticscholar +1 more source
Cell Reports, 2012 Lysine acetylation is a major posttranslational modification involved in a broad array of physiological functions. Here, we provide an organ-wide map of lysine acetylation sites from 16 rat tissues analyzed by high-resolution tandem mass spectrometry. We
Alicia Lundby +10 more
doaj +1 more source
Antioxidants, 2023 Oxidative stress adaptation strategies are important to cell function and are linked to cardiac, neurodegenerative disease, and cancer. Representatives of the Archaea domain are used as model organisms based on their extreme tolerance to oxidants and ...
Ricardo L. Couto-Rodríguez +3 more
doaj +1 more source
Proline cis-trans isomerization is influenced by local lysine acetylation-deacetylation
, 2014 Acetylation of lysine residues has several characterised functions in chromatin. These include neutralization of the lysine’s positive charge to directly influence histone tail-DNA/internucleosomal interactions or indirect effects via bromodomain ...
Jane Mellor, Françoise S. Howe
core +1 more source
Identification of lysine acetylome in cervical cancer by label-free quantitative proteomics
Cancer Cell International, 2020 Background Lysine acetylation is a post-translational modification that regulates a diversity of biological processes, including cancer development. Methods Here, we performed the quantitative acetylproteomic analysis of three primary cervical cancer ...
Lu Zhang +7 more
doaj +1 more source
Acetylation-dependent coupling between G6PD activity and apoptotic signaling
Nature Communications, 2023 Lysine acetylation has been discovered in thousands of non-histone human proteins, including most metabolic enzymes. Deciphering the functions of acetylation is key to understanding how metabolic cues mediate metabolic enzyme regulation and cellular ...
Fang Wu +7 more
doaj +1 more source
Abnormal lysine acetylation with postovulatory oocyte aging [PDF]
Reproductive Medicine and Biology, 2013 AbstractBackgroundA postovulatory mammalian oocyte decreases developmental potential with in vivo aging in the oviduct or in vitro aging in the culture dish. The mechanism underlying oocyte aging still largely remains an enigma. Accumulating data suggest that the epigenetic alterations such as histone acetylation are also associated with postovulatory ...
Ah Reum, Lee +3 more
openaire +2 more sources
Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
Lysine Acetylation Stoichiometry Analysis at the Proteome Level
, 2021 Lysine acetylation is a widespread posttranslational modification (PTM) in all kingdoms of live. A large number of proteins involved in most of biological pathways are targets of this PTM. The lysine acetylation is a reversible modification controlled by
Sergio Encarnación-Guevara +6 more
core +2 more sources
Lysine acetylation in cyanobacteria: emerging mechanisms and functions. [PDF]
Biochem Soc TransCyanobacteria are ancient and abundant photosynthetic prokaryotes that play crucial roles in global carbon and nitrogen cycles. They exist in a variety of environments and have been used extensively as model organisms for studies of photosynthesis and environmental adaptation.
Liu X, Yang M, Ge F, Zhao J.
europepmc +3 more sources