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A Comprehensive Analysis of the Lysine Acetylome in the Aquatic Animals Pathogenic Bacterium Vibrio mimicus [PDF]
Frontiers in Microbiology, 2022 Protein lysine acetylation is an evolutionarily conserved post-translational modification (PTM), which is dynamic and reversible, playing a crucial regulatory role in almost every aspect of metabolism, of both eukaryotes and prokaryotes.
Wanxin Li, Sean Monaghan, Rowena Hoare
exaly +4 more sources
Nicotinamide Mononucleotide Administration Amends Protein Acetylome of Aged Mouse Liver
Cells, 2022 It is known that the activities of nicotine adenine dinucleotide (NAD+)-dependent deacetylase decline in the aging mouse liver, and nicotinamide mononucleotide (NMN)-mediated activation of deacetylase has been shown to increase healthspans.
Songbiao Zhu, Haiteng Deng
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Food Science and Human Wellness, 2023 Modern technological lifestyles promote allergic diseases, especially food allergies. The underlying molecular mechanisms remain to be uncovered. Protein acetylation is one of the most important post-translational modifications, and it is involved in ...
Fazheng Ren
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Emerging Microbes and Infections, 2019 Lysine acetylation and succinylation are both prevalent protein post-translational modifications (PTMs) in bacteria species, whereas the effect of the cross-talk between both PTMs on bacterial biological function remains largely unknown.
Zujie Yao, Xiangmin Lin, Wang Yuqian
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Microbiology Spectrum, 2023 Protein acetylation can quickly modify the physiology of bacteria to respond to changes in environmental or nutritional conditions, but little information on these modifications is available in rhizobia.
Yanan Liu +5 more
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Sirtuin 2 promotes human cytomegalovirus replication by regulating cell cycle progression
mSystems, 2023 The ability to modulate host cell cycle progression is a requirement of many human viruses in order to facilitate their replication and propagation. Nuclear-replicating DNA viruses frequently stall the host cell cycle in G1 to avoid competition with host
Cora N. Betsinger +6 more
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Medicinal chemistry of histone deacetylase inhibitors [PDF]
Arhiv za farmaciju, 2021 Today, we are witnessing an explosion of scientific concepts in cancer chemotherapy. It has been considered for a long time that genetic instability in cancer should be treated with drugs that directly damage the DNA. Understanding the molecular basis of
Ružić Dušan +3 more
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Antibiotics, 2022 The antibiotic resistance of Edwardsiella tarda is becoming increasingly prevalent, and thus novel antimicrobial strategies are being sought. Lysine acylation has been demonstrated to play an important role in bacterial physiological functions, while its
Yuying Fu +7 more
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An Alternative Strategy for Pan-acetyl-lysine Antibody Generation. [PDF]
PLoS ONE, 2016 Lysine acetylation is an important post-translational modification in cell signaling. In acetylome studies, a high-quality pan-acetyl-lysine antibody is key to successful enrichment of acetylated peptides for subsequent mass spectrometry analysis.
Sun-Yee Kim +9 more
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Frontiers in Immunology, 2021 As a subgroup of CD4+ T helper cells, follicular helper T (Tfh) cells provide help to germinal center B cells and mediate the development of long-lived humoral immunity.
Ming Zhao +11 more
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