Results 41 to 50 of about 2,693 (199)
Exploring the Yeast Acetylome Using Functional Genomics [PDF]
Cell, 2012 Lysine acetylation is a dynamic posttranslational modification with a well-defined role in regulating histones. The impact of acetylation on other cellular functions remains relatively uncharacterized. We explored the budding yeast acetylome with a functional genomics approach, assessing the effects of gene overexpression in the absence of lysine ...
Kaluarachchi Duffy, Supipi +6 more
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Frontiers in Molecular Biosciences, 2017 Lysine acetylation is a prevalent post-translational modification in both eukaryotes and prokaryotes. Whereas this modification is known to play pivotal roles in eukaryotes, the function and extent of this modification in prokaryotic cells remain largely
Jiahn-Haur Liao +19 more
doaj +1 more source
Comparison of the protein acetylome of endothelial cells upon shear flow and resveratrol treatment [PDF]
, 2013 Background: Posttranslational acetylation/deacetylation known as the acetylome is important in regulating protein activity. Shear flow (SF) and resveratrol (RSV) are two stimuli that represent physical and chemical signal separately.
Li, Fu-An; Institute of Biomedical Sciences, Academia Sinica, Taipei, Taiwan +4 more
core +1 more source
Frontiers in Veterinary Science, 2023 Lysine acetylation modification is a dynamic and reversible post-translational modification, which plays an important role in the metabolism and pathogenicity of pathogenic bacteria.
Xing Xiao +15 more
doaj +1 more source
Frontiers in Microbiology, 2020 Infection with Vibrio vulnificus is notorious for its atypical clinical manifestations and irreversible disease progression. Lysine acetylation is a conserved post-translational modification (PTM) that plays a critical regulatory role in diverse cellular
Rui Pang +12 more
doaj +1 more source
Proteome-wide lysine acetylation in cortical astrocytes and alterations that occur during infection with brain parasite Toxoplasma gondii. [PDF]
PLoS ONE, 2015 Lysine acetylation is a reversible post-translational modification (PTM) that has been detected on thousands of proteins in nearly all cellular compartments.
Anne Bouchut +4 more
doaj +1 more source
Frontiers in Genetics, 2022 Suberoylanilide hydroxamic acid (SAHA), a famous histone deacetylase (HDAC) inhibitor, has been utilized in clinical treatment for cutaneous T-cell lymphoma.
Huichao Huang +11 more
doaj +1 more source
Construction of a Quantitative Acetylomic Tissue Atlas in Rice (Oryza sativa L.)
Molecules, 2018 PKA (protein lysine acetylation) is a key post-translational modification involved in the regulation of various biological processes in rice. So far, rice acetylome data is very limited due to the highly-dynamic pattern of protein expression and PKA ...
Zhiyong Li +6 more
doaj +1 more source
Frontiers in Cellular Neuroscience, 2022 Nε-lysine acetylation is a reversible posttranslational modification (PTM) involved in multiple physiological functions. Genetic and animal studies have documented the critical roles of protein acetylation in brain development, functions, and various ...
Yuhua Ji +9 more
doaj +1 more source
Acetylome in Human Fibroblasts From Parkinson's Disease Patients [PDF]
Frontiers in Cellular Neuroscience, 2018 Parkinson's disease (PD) is a multifactorial neurodegenerative disorder. The pathogenesis of this disease is associated with gene and environmental factors. Mutations in leucine-rich repeat kinase 2 (LRRK2) are the most frequent genetic cause of familial and sporadic PD.
Sokhna M. S. Yakhine-Diop +27 more
openaire +6 more sources