Results 51 to 60 of about 2,693 (199)
Systematic Analysis of the Lysine Acetylome in Vibrio parahemolyticus
, 2016 Lysine acetylation of proteins is a major post-translational modification that plays an important regulatory role in almost every aspect of cells, both eukaryotes and prokaryotes.
Liangyou Wen (1784590) +5 more
core +3 more sources
ATRIP Deacetylation by SIRT2 Drives ATR Checkpoint Activation by Promoting Binding to RPA-ssDNA
Cell Reports, 2016 The ataxia telangiectasia-mutated and Rad3-related (ATR) kinase checkpoint pathway maintains genome integrity; however, the role of the sirtuin 2 (SIRT2) acetylome in regulating this pathway is not clear.
Hui Zhang +22 more
doaj +1 more source
Chronic exercise remodels the lysine acetylome in the mouse hippocampus
Frontiers in Molecular Neuroscience, 2022 Physical exercise benefits hippocampal function through various molecular mechanisms. Protein acetylation, a conserved and widespread post-translational modification, is involved in the synaptic plasticity and memory. However, whether exercise can change global acetylation and the role of acetylated proteins in the hippocampus have remained largely ...
Ping Qian +15 more
openaire +3 more sources
Frontiers in Cellular and Infection Microbiology, 2018 Protein lysine acetylation is recognized as an important reversible post translational modification in all domains of life. While its primary roles appear to reside in metabolic processes, lysine acetylation has also been implicated in regulating ...
Carsten Jers +7 more
doaj +1 more source
Circadian acetylome reveals regulation of mitochondrial metabolic pathways [PDF]
Proceedings of the National Academy of Sciences, 2013 The circadian clock is constituted by a complex molecular network that integrates a number of regulatory cues needed to maintain organismal homeostasis. To this effect, posttranslational modifications of clock proteins modulate circadian rhythms and are thought to convert physiological signals into changes in protein regulatory ...
Selma, Masri +8 more
openaire +2 more sources
mSystems, 2016 N ε-Lysine acetylation has been recognized as a ubiquitous regulatory posttranslational modification that influences a variety of important biological processes in eukaryotic cells.
Valerie J. Carabetta +4 more
doaj +1 more source
Dual lysine and N‐terminal acetyltransferases reveal the complexity underpinning protein acetylation
Molecular Systems Biology, 2020 Protein acetylation is a highly frequent protein modification. However, comparatively little is known about its enzymatic machinery. N‐α‐acetylation (NTA) and ε‐lysine acetylation (KA) are known to be catalyzed by distinct families of enzymes (NATs and ...
Willy V Bienvenut +21 more
doaj +1 more source
LAFEM: A scoring model to evaluate functional landscape of lysine acetylome
, 2023 <p>The LAFEM application, the commands of BLAST+ to construct database and blast, SASA score of 23391 proteins, quantitative acetylome results (PDC000233 and PDC000224) of MaxQuant, DEAS and non-DEAS respectively in the 2 acetylomes, diso files ...
Liang, Junze
core +1 more source
Protein intrinsic disorder in the acetylome of intracellular and extracellular Toxoplasma gondii
, 2018 Acetylome analysis of extracellular tachyzoites of the protozoan parasite Toxoplasma ...
William J. Sullivan Jr. (704746) +3 more
core +1 more source
, 2021 Zymomonas mobilis, a promising candidate for industrial biofuel production, is capable of nitrogen fixation naturally without hindering ethanol production. However, little is known about the regulation of nitrogen fixation in Z. mobilis.
Sawar Khan (6324086) +6 more
core +1 more source