Results 21 to 30 of about 2,693 (199)

The Tip60 acetylome is a hallmark of the proliferative state in Drosophila. [PDF]

Nucleic Acids Res
Abstract The acetyltransferase KAT5/Tip60 is an epigenetic regulator of transcription and the DNA damage response. In Drosophila , Tip60 acetylates histones as part of the DOM-A complex, but it is unclear whether it has other substrates.
Apostolou Z, Venkatasubramani AV, Kopp LC, Kars G, Scacchetti A, Campos-Sparr A, Schauer T, Imhof A, Becker PB.   +8 more
europepmc   +6 more sources

Insights Into the Role of Lysine Acetylation of Non-Histone Proteins in Plant Immunity. [PDF]

Plant Cell Environ
ABSTRACT Plant immunity is regulated by numerous transcriptional and posttranslational mechanisms. Among these, lysine acetylation, which is controlled by lysine acetyltransferases (KATs) and lysine deacetylases (KDACs), has been extensively studied, particularly in the context of epigenetic regulation through histone acetylation.
Villette J, Ilbert C, Aimé S, Truong HN, Adrian M, Bourque S.   +5 more
europepmc   +2 more sources

Acetyl‐Phosphate Dependent Protein Acetylation in Neisseria gonorrhoeae [PDF]

MicrobiologyOpen
The disease gonorrhoea is caused by the sexually transmitted pathogen Neisseria gonorrhoeae. This bacterium is an obligate human pathogen that can survive intracellularly through the expression of specific pathogenicity determinants.
Ernesto F. D. Parga, Paige A. Wolverson, Mark O. Collins, Oliver Heaney, Joby Cole, Luke R. Green, Jonathan G. Shaw   +6 more
doaj   +2 more sources

Acetylome Analysis in Vibrio vulnificus MO6-24/O Reveals Extensive Lysine Acetylation in Carbon Metabolism and Protein Synthesis Pathways: A Pilot Study [PDF]

Pathogens
Vibrio vulnificus (V. vulnificus) is a type of bacterium commonly found in estuarine environments. It can cause necrotizing wound infections and sepsis, both of which are associated with high mortality rates.
Yurong Song, Ming Cheng, Xiaoling Li, Ying Wang, Yulong Zong, Jing Li, Guozhong Chen, Shiyong Chen, Yuan Cao   +8 more
doaj   +2 more sources

The protein acetylome and the regulation of metabolism.

Trends in Plant Science, 2012
Acetyl-coenzyme A (CoA) is a central metabolite involved in numerous anabolic and catabolic pathways, as well as in protein acetylation. Beyond histones, a large number of metabolic enzymes are acetylated in both animal and bacteria, and the protein ...
Poirier Y, Xing S
core   +4 more sources

Global Profiling of the Proteome and Acetylome in Mice with Abdominal Aortic Aneurysms. [PDF]

ACS Omega
Abstract Background Abdominal Aortic Aneurysm (AAA) is a life-threatening vascular condition characterized by a progressive dilation of the abdominal aorta and a high risk of rupture. Currently, no effective pharmacological therapies are available, and treatment relies mainly on surgical intervention.
Zhang L, Yang B, Ding T, Zhao Y, Yang Y, Tang X, Wu Y, Wang Q, Zhang Z, Shi C, Han R, Zhang X, Liu J, Yang J.   +13 more
europepmc   +3 more sources

Dynamic global acetylation remodeling during the yeast heat shock response [PDF]

Genome Biology
Background All organisms experience stress and must rapidly respond to changing conditions. Thus, cells have evolved sophisticated rapid-response mechanisms such as post-translational protein modification to rapidly and reversibly modulate protein ...
Rebecca E. Hardman-Kavanaugh, Aaron J. Storey, Tara N. Stuecker, Stephanie E. Hood, Gregory A. Barrett-Wilt, Venkata R. Krishnamurthi, Yong Wang, Stephanie D. Byrum, Samuel G. Mackintosh, Rick D. Edmondson, Wayne P. Wahls, Alan J. Tackett, Jeffrey A. Lewis   +12 more
doaj   +2 more sources

A Hiplot‐based web service for cold atmospheric plasma high‐throughput data integration and analysis on breast cancer [PDF]

iMeta
Incremental evidence on the effect of cold atmospheric plasma (CAP) in specifically killing transformed cells and advances in sequencing technologies at multiple omics have led to the demand of in‐depth exploration on the mechanisms of action driving the
Xiaofeng Dai, Mingjie Wang, Yang Liu
doaj   +2 more sources

Acetylome Analyses Provide New Insights Into the Effects of Childhood Allergic Rhinitis on Olfactory Bulb-Dependent Olfactory Impairment. [PDF]

Allergy
Allergy, Volume 81, Issue 5, Page 1891-1894, May 2026.
Wang R, Xu Z, Zhang Y, Wang Q, Li M, Liang J, Zhan X, Lu Y, Yuan J, Wang S, Gu Q.   +10 more
europepmc   +2 more sources

Adaptation of White Adipocytes to Cooler Temperatures: Impacts on Energy Metabolism and Protein Acetylation. [PDF]

FASEB J
Cultured white adipocytes exposed to 31°C undergo cell‐autonomous metabolic adaptation characterized by enhanced mitochondrial function and widespread remodeling of the mitochondrial acetylome. Acetyl‐proteomic and metabolomic profiling identified mitochondria‐associated proteins, including SHMT2 and PCCA, whose acetylation changes were linked to ...
Mori H, Hariri H, Moe W, Durham S, Guzman Y, Paulsson E, Simmermon RC, Bhanderi PB, Peterson SK, Dickson MJ, Evans CR, MacDougald OA.   +11 more
europepmc   +2 more sources