Results 141 to 150 of about 4,831 (203)

Cholangiocarcinoma PDHA1 succinylation suppresses macrophage antigen presentation via alpha-ketoglutaric acid accumulation

open access: yesNature Communications
Gemcitabine combined with cisplatin is the first-line chemotherapy for advanced cholangiocarcinoma, but drug resistance remains a challenge, leading to unsatisfactory therapeutic effect.
Ning Zhang   +23 more
doaj   +1 more source

Rhamnolipid Enhances the Nitrogen Fixation Activity of Azotobacter chroococcum by Influencing Lysine Succinylation. [PDF]

open access: yesFront Microbiol, 2021
Li J   +9 more
europepmc   +1 more source

Sirtuin 5 inhibits mitochondrial metabolism in liver cancer cells and promotes apoptosis by mediating the desuccinylation of CS

open access: yesFrontiers in Immunology
BackgroundCitrate synthase (CS) is a key rate-limiting enzyme in the tricarboxylic acid (TCA) cycle and plays a crucial role in cancer progression. However, the mechanism by which CS promotes liver cancer growth remains unclear.
Huimin Cao   +8 more
doaj   +1 more source

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