Results 61 to 70 of about 1,405,084 (401)

Shape-dependent optoelectronic cell lysis [PDF]

, 2014
We show an electrical method to break open living cells amongst a population of different cell types, where cell selection is based upon their shape.
Bao, Barrett, Brown, Carlo, Chen, Chiou, Edd, Gimsa, Gorges, Grosse, Ho, Jen, Kumar, Li, Lin, Linke, Mahalanabis, McElligott, Neale, Pucihar, Reboud, Sale, Sowemimo-Coker, Tsong, Valley, Valley, Valley, Vandeventer, Zimmermann   +28 more
core   +1 more source

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

FEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang, Satoshi Hashimoto, Sota Ito, Chisato Kikuguchi, Miho Hoshi, Kiyoshi Yamaguchi, Yoichi Furukawa, Toru Suzuki, Toshifumi Inada   +8 more
wiley   +1 more source

Absence of evidence for viral infection in colony-embedded cyanobacterial isolates from the Curonian Lagoon

Oceanologia, 2014
The aim of the present study was to assess the frequency of viral infections in colony-embedded cells of the cyanobacteria Aphanizomenon flos-aquae and Microcystis aeruginosa collected from the brackish Curonian Lagoon. Natural and mitomycin C-treated A.
Sigitas Sulcius, Juozas Staniulis, Ricardas Paskauskas   +2 more
doaj   +1 more source

Insulin-like growth factor I is an independent coregulatory modulator of natural killer (NK) cell activity. [PDF]

, 1996
We aimed to investigate the natural killer (NK) cell activity in hGH-deficient adults and to analyze the effect of insulin-like growth factor (IGF)-I in uivo and in vitro on NK cell activity.
C J Auernhammer, C J Strasburger, H Feldmeier, K Pachmann, R Nass   +4 more
core   +1 more source

Caspase‐1‐dependent pore formation during pyroptosis leads to osmotic lysis of infected host macrophages

Cellular Microbiology, 2006
Salmonella enterica serovar Typhimurium invades host macrophages and induces a unique caspase‐1‐dependent pathway of cell death termed pyroptosis, which is activated during bacterial infection in vivo.
S. Fink, B. Cookson
semanticscholar   +1 more source

Mechanisms of parasite‐mediated disruption of brain vessels

FEBS Letters, EarlyView.
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira, Sílvia Arroz‐Madeira, Cláudio A. Franco, Sara Silva Pereira   +3 more
wiley   +1 more source

Phage-Encoded LuxR-Type Receptors Responsive to Host-Produced Bacterial Quorum-Sensing Autoinducers

mBio, 2019
Quorum sensing (QS) is a process of cell-to-cell communication that bacteria use to orchestrate collective behaviors. QS relies on the cell-density-dependent production, accumulation, and receptor-mediated detection of extracellular signaling molecules ...
Justin E. Silpe, Bonnie L. Bassler
doaj   +1 more source

Comparison of Lysis and Detachment Sample Preparation Methods for Cultured Triple-Negative Breast Cancer Cells Using UHPLC–HRMS-Based Metabolomics

Metabolites, 2022
Dysregulation of cellular metabolism is now a well-recognized hallmark of cancer. Studies investigating the metabolic features of cancer cells have shed new light onto processes in cancer cell biology and have identified many potential novel treatment ...
Blake R. Rushing, Madison Schroder, Susan C. J. Sumner   +2 more
doaj   +1 more source

Lysis, lysogeny and virus–microbe ratios

Nature, 2016
We show that neither the Piggyback-the-Winner model nor coral reef virome data presented in Knowles et al. [1] support a mechanistic link between increases in lysogeny, suppression of lysis, and the decline of the virus-to-microbial cell ratio (VMR) at ...
J. Weitz, S. Beckett, Jennifer R. Brum, B. B. Cael, J. Dushoff   +4 more
semanticscholar   +1 more source

Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions

FEBS Letters, EarlyView.
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf, Nicholas F. Downing, Kaitlyn M. Mills, Samuel C. Metcalfe, Alexander E. Kritzer, Lindsey D. Mayo, Peter C. Hollenhorst   +6 more
wiley   +1 more source