Results 141 to 150 of about 24,193 (235)

Calcium puffs are generic InsP3-activated elementary calcium signals and are downregulated by prolonged hormonal stimulation to inhibit cellular calcium responses [PDF]

open access: yes, 2001
Elementary Ca2+ signals, such as "Ca2+ puffs", which arise from the activation of inositol 1,4,5-trisphosphate receptors, are building blocks for local and global Ca2+ signalling.
Berridge, Michael J.   +11 more
core  

Intranuclear Signaling Cascades Triggered by Nuclear GPCRs

open access: yes, 2016
G protein-couped receptors (GPCRs) play a key role on cellular membranes, where they respond to a broad array of extracellular signals such as lipids, peptides, proteins and sensory agents.
AMMENDOLA, ROSARIO   +4 more
core   +1 more source

Frontiers of antifibrotic therapy in systemic sclerosis [PDF]

open access: yes, 2017
Although fibrosis is becoming increasingly recognized as a major cause of morbidity and mortality in modern societies, targeted anti-fibrotic therapies are still not approved for most fibrotic disorders. However, intense research over the last decade has
Abraham, DJ   +5 more
core  

Inhibition of lysophosphatidic acid receptors 1 and 3 attenuates atherosclerosis development in LDL-receptor deficient mice. [PDF]

open access: yesSci Rep, 2016
Kritikou E   +8 more
europepmc   +1 more source

Expression and function of lysophosphatidic acid receptors (LPARs) 1 and 3 in human hepatic cancer progenitor cells. [PDF]

open access: yesOncotarget, 2016
Zuckerman V   +6 more
europepmc   +1 more source

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