Calcium puffs are generic InsP3-activated elementary calcium signals and are downregulated by prolonged hormonal stimulation to inhibit cellular calcium responses [PDF]
Elementary Ca2+ signals, such as "Ca2+ puffs", which arise from the activation of inositol 1,4,5-trisphosphate receptors, are building blocks for local and global Ca2+ signalling.
Berridge, Michael J. +11 more
core
Intranuclear Signaling Cascades Triggered by Nuclear GPCRs
G protein-couped receptors (GPCRs) play a key role on cellular membranes, where they respond to a broad array of extracellular signals such as lipids, peptides, proteins and sensory agents.
AMMENDOLA, ROSARIO +4 more
core +1 more source
Frontiers of antifibrotic therapy in systemic sclerosis [PDF]
Although fibrosis is becoming increasingly recognized as a major cause of morbidity and mortality in modern societies, targeted anti-fibrotic therapies are still not approved for most fibrotic disorders. However, intense research over the last decade has
Abraham, DJ +5 more
core
Diverse Effects of Lysophosphatidic Acid Receptors on Ovarian Cancer Signaling Pathways. [PDF]
Onallah H, Davidson B, Reich R.
europepmc +1 more source
G-Protein-Coupled Lysophosphatidic Acid Receptors and Their Regulation of AKT Signaling. [PDF]
Riaz A, Huang Y, Johansson S.
europepmc +1 more source
Inhibition of lysophosphatidic acid receptors 1 and 3 attenuates atherosclerosis development in LDL-receptor deficient mice. [PDF]
Kritikou E +8 more
europepmc +1 more source
Lysophosphatidic Acid Receptors LPAR5 and LPAR2 Inversely Control Hydroxychloroquine-Evoked Itch and Scratching in Mice. [PDF]
Fischer C +6 more
europepmc +1 more source
Expression of lysophosphatidic acid receptors in the human lower esophageal sphincter. [PDF]
Feng Y, Liu JF.
europepmc +1 more source
Lysophosphatidic acid receptor 5 (LPAR5; LPA5) [PDF]
openaire +1 more source
Expression and function of lysophosphatidic acid receptors (LPARs) 1 and 3 in human hepatic cancer progenitor cells. [PDF]
Zuckerman V +6 more
europepmc +1 more source

