Results 141 to 150 of about 39,610 (238)
Bone Metastasis: Molecular Mechanisms, Clinical Management, and Therapeutic Targets
This figure emphasizes current understanding of the regulatory networks, approach of diagnose, available preclinical models and clinical management of bone metastasis. to guide future therapeutic development. A deep understanding of these aspects enables the prevention of bone metastasis and the implementation of effective therapeutic strategies ...
Jingyuan Wen +5 more
wiley +1 more source
Possible Involvement of Lysophospholipids in Severe Asthma as Novel Lipid Mediators
In severe asthma, symptoms are unstable despite intensive treatment based on high doses of inhaled corticosteroids and on-demand use of oral corticosteroids.
Hiroaki Kume +3 more
doaj +1 more source
Lipidomic and proteomic analysis revealed large‐scale differences in the midgut composition of the honeybee Apis mellifera and the buff‐tailed bumblebee Bombus terrestris. These differences correlated to increased insecticide absorption in the bumblebee when using an ex vivo Ussing chamber and subsequently in vivo feeding assay (created in Biorender ...
Emmanouil Kokkas +7 more
wiley +1 more source
The phospholipase iPLA2γ is a major mediator releasing oxidized aliphatic chains from cardiolipin, integrating mitochondrial bioenergetics and signaling [PDF]
Gross, Richard W +6 more
core +2 more sources
Assessing the microbiome of captive Pocillopora verrucosa corals showed that populations of proposed microbial symbiont Endozoicomonas could only be maintained when corals were co‐cultured with Chromis viridis damselfish and supplied live feeds.
Rachel C. Neil +7 more
wiley +1 more source
Lifestyle implications of the paradox and management of oxidative stress in sperm
Abstract figure legend Lifestyle factors influencing male fertility. Schematic overview of lifestyle factors with beneficial (left) and detrimental (right) effects on male fertility. A balanced diet, regular moderate physical activity and stress management strategies support sperm function and redox homeostasis.
Giuseppe T. Patané +6 more
wiley +1 more source
Tks4‐Targeted Gene Therapy Inhibited White Adipocyte Hypertrophy in Mice
Tks4 knockout or knockdown by AAV mediated shRNA both successfully restricted adipocyte hypertrophy in high fat diet. The reduction of TAG was validated by biochemistry and lipidomics analyses. This study suggested a potential of Tks4 targeted therapy in obesity intervention. ABSTRACT Obesity is one of the most prevalent public health issues worldwide,
Meng Tian +5 more
wiley +1 more source
Retinal de novo lipogenesis coordinates neurotrophic signaling to maintain vision [PDF]
Adak, Sangeeta +11 more
core +2 more sources
Minghao Gu,1,2 SenSen Lv,1 Yihui Song,3 Hong Wang,4 Xingyu Zhang,5 Jing Liu,1 Deshun Liu,1 Xiudi Han,1 Xuedong Liu1 1Department of Respiratory and Critical Care Medicine, Qingdao Municipal Hospital, Qingdao, 266011, People’s Republic of China; 2School of
Gu M +8 more
doaj

