Identification of plasma lipid metabolism and potential biomarkers in patients with different coronary occlusive acute myocardial infarction [PDF]
Frontiers in Cell and Developmental BiologyAcute myocardial infarction (AMI) is the main cause of death worldwide. We aim to compare the differences in plasma lipid metabolites between AMI patients and normal controls to search for biomarker molecules for AMI with different infarct sites.
Hao Chen +4 more
doaj +2 more sources
Untargeted Metabolomics Reveals Metabolic Reprogramming Linked to HCC Risk in Late Diagnosed Tyrosinemia Type 1 [PDF]
MetabolitesBackground/Objectives: Tyrosinemia type 1 (HT-1) is a treatable inherited disorder characterized by disrupted tyrosine metabolism, leading to severe liver, renal, and occasionally neurological dysfunction.
Anna Sidorina +10 more
doaj +2 more sources
Plasma lipidomic and metabolomic profiles in high‐grade glioma patients before and after 72‐h presurgery water‐only fasting [PDF]
Molecular OncologyGlioblastoma (GB) is the most aggressive primary brain tumor with poor prognosis despite multimodal therapy. Calorie‐restricted diets have emerged as putative strategies to augment anticancer therapies. We employed UHPLC‐high‐resolution mass spectrometry
Iris Divé +7 more
doaj +2 more sources
Lipid profiling of Parkinson’s disease brain highlights disruption in Lysophosphatidylcholines, and triacylglycerol metabolism [PDF]
npj Parkinson's DiseaseParkinson’s disease (PD) is the second most common neurodegenerative disorder following Alzheimer’s disease, with a 1.5 times higher prevalence in males.
Ali Yilmaz +8 more
doaj +2 more sources
Metabolic profiles of squamous cell lung carcinoma and diagnostic model construction [PDF]
Scientific ReportsCancer cells exhibit metabolic reprogramming to fulfill their increased demands for abnormal growth and proliferation. We studied metabolic profiles of squamous cell lung carcinoma (LUSC).
Kyung Soo Kim +5 more
doaj +2 more sources
Lysophosphatidylcholines and phosphatidylcholines as biomarkers for stroke recovery
Frontiers in Neurology, 2022 Stroke is a serious global public health issue, associated with severe disability and high mortality rates. Its early detection is challenging, and no effective biomarkers are available.
Meiling Huang +8 more
doaj +1 more source
Frontiers in Endocrinology, 2023 AimsThis study aimed to explore associations of mannan-binding lectin-associated serine protease (MASP) levels in early pregnancy with gestational diabetes mellitus (GDM).
Ming Gao +16 more
doaj +1 more source
Frontiers in Cardiovascular Medicine, 2021 Aortic dissection (AD) is a catastrophic cardiovascular emergency with a poor prognosis, and little preceding symptoms. Abnormal lipid metabolism is closely related to the pathogenesis of AD.
Huang Huang +14 more
doaj +1 more source
Metabolites, 2021 The use of oral contraceptives (OCs) has been associated with elevated blood cortisol concentrations. However, metabolic downstream effects of OC intake are not well described.
Clara Eick +10 more
doaj +1 more source
ATP Release Drives Inflammation with Lysophosphatidylcholine [PDF]
ImmunoHorizons, 2020 Abstract Lysophosphatidylcholine (LPC), a dominant lipid component of oxidized low-density lipoprotein, plays a major role in inflammation associated with atherosclerosis and neurodegenerative disorders. It activates inflammatory responses from macrophages, neuronal cells, and endothelial cells.
Sana, Ismaeel, Ayub, Qadri
openaire +3 more sources