Development of an in vitro metabolic dysfunction-associated steatohepatitis model to investigate altered drug metabolizing enzymes, transport proteins, and hepatobiliary disposition [PDF]
Frontiers in PharmacologyIntroductionMetabolic dysfunction-associated steatotic liver disease (MASLD) is estimated to affect ∼30% of adults globally. The progressive form of MASLD, metabolic dysfunction-associated steatohepatitis (MASH), is a leading cause of chronic liver ...
William A. Murphy +9 more
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Effects of Lysophospholipids on the Antioxidant Capacity, Digestive Performance, and Intestinal Microbiota of Litopenaeus vannamei [PDF]
BiologyThis study seeks to assess the impact of varying concentrations of lysophospholipids on the antioxidant capacity, digestive performance, and intestinal microbiota of L. vannamei.
Hailiang Yan +6 more
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Impact of dietary lysophospholipids supplementation on growth performance, meat quality, and lipid metabolism in finishing bulls fed diets varying in fatty acid saturation [PDF]
Journal of Animal Science and BiotechnologyBackground The objective of this study was to evaluate the effects of dietary fatty acids (FA) saturation and lysophospholipids supplementation on growth, meat quality, oxidative stability, FA profiles, and lipid metabolism of finishing beef bulls ...
Meimei Zhang +7 more
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Heat-moisture-treated rice improves oral glucose tolerance by modulating serum and fecal metabolites in mice [PDF]
Frontiers in NutritionBackground/objectiveHeat-moisture treatment (HMT) can increase the composition of resistant starch and reduce the glycemic index in rice. However, the effect of long-term HMT-rice feeding is unknown.
Jinming Zhang +7 more
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Cytoprotective Effects of Lysophospholipids from Sea Cucumber Holothuria atra. [PDF]
PLoS ONE, 2015 Lysophospholipids are important signaling molecules in animals and metazoan cells. They are widely distributed among marine invertebrates, where their physiological roles are unknown. Sea cucumbers produce unique lysophospholipids.
Yoshifumi Nishikawa +9 more
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Frontiers in Physiology, 2021 Phospholipids (PL) are converted into lipid biomarkers by the action of phospholipases and reactive oxygen species (ROS), which are activated or released under certain physiological and pathophysiological conditions.
Kathrin M. Engel +3 more
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Dual Role of ACBD6 in the Acylation Remodeling of Lipids and Proteins
Biomolecules, 2022 The transfer of acyl chains to proteins and lipids from acyl-CoA donor molecules is achieved by the actions of diverse enzymes and proteins, including the acyl-CoA binding domain-containing protein ACBD6.
Eric Soupene, Frans A. Kuypers
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Class II Phosphoinositide 3-Kinases Contribute to Endothelial Cells Morphogenesis [PDF]
, 2013 PMCID: PMC3539993This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are ...
Catapano, AL +8 more
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Cancer Medicine, 2022 Background Numerous studies have investigated the possible involvement of eicosanoids, lysophospholipids, and sphingolipids in cancer. We considered that comprehensive measurement of these lipid mediators might provide a better understanding of their ...
Makoto Kurano, Eri Sakai, Yutaka Yatomi
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Specific inhibition of rat brain phospholipase D by lysophospholipids
Journal of Lipid Research, 2000 Although the importance of phospholipase D (PLD) in signal transduction in mammalian cells is well documented, the negative regulation of PLD is poorly understood. This is primarily due to a lack of known specific inhibitors of PLD. We herein report that
Stephen B. Ryu, Jiwan P. Palta
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