Results 121 to 130 of about 17,757 (160)

Integrating gut microbiota and metabolomics in pediatric inflammatory bowel disease: insights into pathogenesis and potential role of precision medicine. [PDF]

Eur J Med Res
Dong R, Meng X, Hu H, Pan J, Wang W.
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Microglia-specific regulation of lipid metabolism in Alzheimer's disease revealed by microglial depletion in 5xFAD Mice. [PDF]

Nat Commun
Xu Z, Kiani Shabestari S, Barannikov S, Bieniek KF, Blurton-Jones M, Palavicini JP, Han X.   +6 more
europepmc   +1 more source

The Nutritional Gene Expression Regulation Potential of a Lysolecithin-Based Product. [PDF]

Curr Issues Mol Biol
Van Hoeck V, Spaepen R, Forier B.
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Lysophospholipid remodeling mediated by the LplT and Aas protein complex in the bacterial envelope. [PDF]

J Biol Chem
Niu W, Vu T, Du G, Bogdanov M, Zheng L.
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Plasma-activated water treatment delayed the lipid oxidation and degradation of golden pompano fillets during storage based on lipidomics. [PDF]

Food Chem X
Zhao B, Gong Y, Cao J, Zhang L, Zhang B, Yin F, El-Seedi H, Ye H, Yang J, Liu Z, Wang J, Chen M, Tian Y, Li C.   +13 more
europepmc   +1 more source

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Lysophospholipid Receptors

Annual Review of Pharmacology and Toxicology, 2001
Lysophospholipids (LPs), including lysophosphatidic acid and sphingosine 1-phosphate, produce many cellular effects. However, the prolonged absence of any cloned and identified LP receptor has left open the question of how these lipids actually bring about these effects.
N, Fukushima, I, Ishii, J J, Contos, J A, Weiner, J, Chun   +4 more
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Lysophospholipids--Receptor Revelations

Science, 2001
Upon cell activation, membrane phospholipids are metabolized into potent lysophospholipid (LP) mediators, such as sphingosine 1-phosphate and lysophosphatidic acid. LPs fulfill signaling roles in organisms as diverse as yeast and humans. The recent discovery of G protein–coupled receptors for LPs in higher eukaryotes, and their involvement in ...
T, Hla, M J, Lee, N, Ancellin, J H, Paik, M J, Kluk   +4 more
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Druggable Lysophospholipid Signaling Pathways

2020
Lysophosphatidic acid (LPA) has major roles as a bioactive signaling molecule, with multiple physiological and pathological roles being described in almost every major organ system. In this review we discuss LPA signaling pathways as emerging drug targets for multiple conditions relevant to human health and disease.
Keisuke, Yanagida, William J, Valentine
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Lysophospholipids in Lung Inflammatory Diseases

2021
The lysophospholipids (LPLs) belong to a group of bioactive lipids that play pivotal roles in several physiological and pathological processes. LPLs are derivatives of phospholipids and consist of a single hydrophobic fatty acid chain, a hydrophilic head, and a phosphate group with or without a large molecule attached.
Jing, Zhao, Yutong, Zhao
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