Results 101 to 110 of about 19,633 (273)
Diabetes, Obesity and Metabolism, Volume 28, Issue 5, Page 4243-4252, May 2026.ABSTRACT Aims Circadian regulation of metabolism is an important factor in metabolic health, yet the role of rhythmic metabolites in Type 2 diabetes development remains poorly understood. This study investigated associations between circulating rhythmic metabolites and incident Type 2 diabetes risk and evaluated causal relationships using two‐sample ...
Divya Joshi +10 more
wiley +1 more source
Untargeted metabolomic analysis of human serum samples associated with different levels of red meat consumption: A possible indicator of type 2 diabetes? [PDF]
, 2016 Red meat consumption has been associated with negative health effects. A study to identify biomarkers of meat consumption was undertaken using serum samples collected from combining high resolution mass spectrometry (UPLC-QTof-MS) and chemometrics. Using
Brennan, Sarah F. +6 more
core +1 more source
Emerging Role of Phospholipids and Lysophospholipids for Improving Brain Docosahexaenoic Acid as Potential Preventive and Therapeutic Strategies for Neurological Diseases [PDF]
, 2022 Mayssa Hachem, Houda Nacir
openalex +1 more source
Lysophospholipid interactions with protein targets [PDF]
Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids, 2008 Bioactive lysophospholipids include lysophosphatidic acid (LPA), sphingosine 1-phosphate (S1P), cyclic-phosphatidic acid (CPA) and alkyl glycerolphosphate (AGP). These lipid mediators stimulate a variety of responses that include cell survival, proliferation, migration, invasion, wound healing, and angiogenesis.
openaire +2 more sources
Microcirculation, Volume 33, Issue 4, May 2026.ABSTRACT Objective Perivascular adipose tissue (PVAT) surrounds most peripheral blood vessels and exerts an anti‐contractile influence through paracrine mediators. Although numerous vasoactive factors have been identified, the mechanisms linking adipocyte metabolism to PVAT‐dependent modulation of vascular tone remain poorly defined. Because adipocytes
Miranda Hyatt +9 more
wiley +1 more source
Biomolecules, 2020 The development of high throughput assays for assessing lipid metabolism in metabolic disorders, especially in diabetes research, nonalcoholic fatty liver disease (NAFLD), and nonalcoholic steatohepatitis (NASH), provides a reliable tool for identifying ...
Nicolas Christinat +2 more
doaj +1 more source
Increased expression of two alternative spliced variants of CD1d molecule in human gastric cancer [PDF]
, 2015 Background: CD1d presents glycolipid antigens to invariant natural killer T (iNKT) cells. The role of CD1d in the development of peptic ulcer and gastric cancer has not been revealed, yet.
Ajami, A. +5 more
core
Metabolomics analysis identifies sex-associated metabotypes of oxidative stress and the autotaxin-lysoPA axis in COPD. [PDF]
, 2017 Chronic obstructive pulmonary disease (COPD) is a heterogeneous disease and a leading cause of mortality and morbidity worldwide. The aim of this study was to investigate the sex dependency of circulating metabolic profiles in COPD.Serum from healthy ...
Erle, David J +11 more
core +1 more source
Molecular Plant Pathology, Volume 27, Issue 5, May 2026.Ustilago maydis secreted lipase, Lip3 targets PA and PS and alkalinises the host apoplast, thus promoting virulence. Loss of Lip3 results in reduced apoplastic pH and decreased pathogenicity. ABSTRACT Lipases constitute important virulence factors. By targeting specific lipids involved in various cellular processes, lipases regulate growth, development,
Anisha Roy +2 more
wiley +1 more source
The FASEB Journal, Volume 40, Issue 8, 30 April 2026.Liver‐specific suppression of PLA2G6/iPLA2β by utilizing the short‐hairpin RNA knockdown technique using an adenovirus vector (Ad‐shPLA2G6) altered phospholipid and fatty acid metabolites and suppressed hepatic lipid accumulation, serum triglyceride, and fasting glucose levels.
Kahori Shimizu +11 more
wiley +1 more source