Results 21 to 30 of about 18,174 (203)

Lysophospholipids: A Potential Drug Candidates for Neurodegenerative Disorders

Biomedicines, 2022
Neurodegenerative diseases (NDs) commonly present misfolded and aggregated proteins. Considerable research has been performed to unearth the molecular processes underpinning this pathological aggregation and develop therapeutic strategies targeting NDs ...
Tatsuya Karaki, Hisao Haniu, Yoshikazu Matsuda, Tamotsu Tsukahara   +3 more
doaj   +1 more source

Synergy between serum amyloid A and secretory phospholipase A2

eLife, 2019
Serum amyloid A (SAA) is an evolutionally conserved enigmatic biomarker of inflammation. In acute inflammation, SAA plasma levels increase ~1,000 fold, suggesting that this protein family has a vital beneficial role.
Shobini Jayaraman, Marcus Fändrich, Olga Gursky   +2 more
doaj   +1 more source

Second trimester inflammatory and metabolic markers in women delivering preterm with and without preeclampsia. [PDF]

, 2019
ObjectiveInflammatory and metabolic pathways are implicated in preterm birth and preeclampsia. However, studies rarely compare second trimester inflammatory and metabolic markers between women who deliver preterm with and without preeclampsia.Study ...
A Chaparro, AO Odibo, B Bolar, B Sibai, BD Taylor, Christina Chambers, Christine Dunkel Schetter, DA Enquobahrie, E Turner, Elena Flowers, F Faul, Gretchen Bandoli, H Luan, H Zeisler, J Massé, J Pinto, JE Ramsay, KE Innes, Kelli Ryckman, Kharah M. Ross, KK Ferguson, KM Ross, Laura Jelliffe-Pawlowski, LC Kenny, Liang Liang, LL Jelliffe-Pawlowski, M Austdal, M Swellam, MP Koster, N Visser, R Boij, R Romero, Rebecca J. Baer, RJ Levine, RO Bahado-Singh, S Acikgoz, S Kim, S Kuc, S Schott, Scott Oltman, Sky K. Feuer, SO Diaz, SW Walsh, SW Walsh, T Chaiworapongsa, T Chen, T Nagamatsu   +46 more
core   +1 more source

Effect of lysophospholipids in diets differing in fat contents on growth performance, nutrient digestibility, milk composition and litter performance of lactating sows

Animal, 2017
It is well known that energy plays an important role in sow growth and development. Increasing the utilization of lipids will be beneficial to sows. Emulsifiers are substances which stabilize mixtures and prevent oil and water from separating, thereby ...
P.Y. Zhao, Z.F. Zhang, R.X. Lan, W.C. Liu, I.H. Kim   +4 more
doaj   +1 more source

Investigations of the lysophospholipid composition of human neutrophils under different stimulation conditions by matrix-assisted laser desorption/ionisation time-of-flight mass spectrometry [PDF]

Journal of the Serbian Chemical Society, 2002
Matrix-assisted laser desorption / ionization time-of-flight mass spectrometry (MALDI-TOF MS) is usually used for the analyses of proteins carbohydrates and oligonucleotides.
Petković Marijana, Schiller Jurgen, Müller Matthias, Arnold Klaus, Arnhold Jurgen   +4 more
doaj   +1 more source

Polarization of macrophages toward M2 phenotype is favored by reduction in iPLA2β (group VIA phospholipase A2)* [PDF]

, 2016
Macrophages are important in innate and adaptive immunity. Macrophage participation in inflammation or tissue repair is directed by various extracellular signals and mediated by multiple intracellular pathways.
Ashley, Jason W, Bone, Robert N, Hancock, William D, Nelson, Alexander J, Ramanadham, Sasanka, Tse, Hubert M, Turk, John, Wohltmann, Mary   +7 more
core   +2 more sources

Supplementing female rats with DHA-lysophosphatidylcholine increases docosahexaenoic acid and acetylcholine contents in the brain and improves the memory and learning capabilities of the pups.

Grasas y Aceites, 2010
Docosahexaenoic acid (DHA) is supplied to the foetus and newborn through the mother from their own reserves and their diet. No consensus about the best form to supplement DHA has been established.
A. Valenzuela, S. Nieto, J. Sanhueza, N. Morgado, I. Rojas, P. Zañartu   +5 more
doaj   +1 more source

Plasma lipid biomarker signatures in squamous carcinoma and adenocarcinoma lung cancer patients [PDF]

, 2015
There is a clinical need for reliable biomarkers for lung cancer that permit early diagnosis of the disease and provide prediction of histological phenotype.
AG Serrano, AM Fiorenza, Andrew W. Fogarty, CH Oak, D Kong, David A. Barrett, David R. Baldwin, E Wojcik, GL May, H Ulmer, H Yang, Helen L. Barr, J Castro de, J Chee, J Dong, J Liu, JM Poczobutt, K Yanagisawa, K Yang, L Cheng, M Haag, M Hassanein, M Hassanein, M Murphy, MJ Wakelam, MR Wenk, P Brites, R Angelis de, RA Murphy, RA Murphy, RE Smith, RL Keith, RT Sreseli, S Cedres, Srinivasarao Ravipati, WJ Scott, X Gao, X Zeng, Y Guo, YY Tyurina, ZA Fernandis   +40 more
core   +1 more source

SnapShot: Bioactive Lysophospholipids

Cell, 2012
Lysophosphatidic acid (LPA; monoacyl-glycerol-3-phosphate) and sphingosine 1-phosphate (S1P) are bioactive lysophospholipids that regulate critical biological functions and disease processes. LPA and S1P act on distinct G protein-coupled receptors (GPCRs) that initiate multiple signaling cascades in many cell types.
Moolenaar, Wouter H., Hla, Timothy
openaire   +2 more sources

The component changes of lysophospholipid mediators in colorectal cancer

Tumor Biology, 2019
Although lysophospholipids are known to play an important role in the development and progression of several kinds of cancers, their role in human colorectal cancer is as yet unclear.
Chieko Kitamura, Hirofumi Sonoda, Hiroaki Nozawa, Kuniyuki Kano, Shigenobu Emoto, Koji Murono, Manabu Kaneko, Masaya Hiyoshi, Kazuhito Sasaki, Takeshi Nishikawa, Yasutaka Shuno, Toshiaki Tanaka, Keisuke Hata, Kazushige Kawai, Junken Aoki, Soichiro Ishihara   +15 more
doaj   +1 more source