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Rab27b: A Modulator of Lysosomal Function and Alpha-Synuclein Clearance in Parkinson's Disease. [PDF]
Badell-Grau RA.
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CRISPR screening in neurodegeneration and lysosomal biology: Uncovering disease mechanisms and genetic modifiers. [PDF]
Esmaeili H +4 more
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The transport of lysosomal enzymes
Journal of Supramolecular Structure, 1977AbstractThis paper reviews the experimental evidence for the proposal that hydrolytic enzymes are introduced into lysosomes of cultured fibroblasts only after secretion and receptormediated recapture.
Leonard H. Rome +2 more
exaly +3 more sources
Lysosomal Enzymes in Inflammatory Synovial Effusions
Abstract The concentrations of several polymorphonuclear neutrophilic lysosomal constitutents were quantitated by immunochemical and enzymatic assays in 28 inflammatory and 9 noninflammatory synovial fluids. The quantities of lactoferrin, myeloperoxidase, and enzymatically determined lysozyme were covariate with the neutrophil count ...
Hadler, N. M. +2 more
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Chromatography of lysosomal enzymes
Archives of Biochemistry and Biophysics, 1968Abstract The soluble fraction of rat liver lysosomes has been chromatographed on DEAE-cellulose, Sephadex G-200, and CM-cellulose. Not all of the lysosomal enzymes measured were separated by chromatography on DEAE-cellulose or Sephadex G-200, although separation into groups of enzymes was possible. CM-cellulose chromatography gave the best resolution.
C, Beck +4 more
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Lysosomes, Lysosomal Enzymes, and Cancer
1992Publisher Summary Lysosomes are membrane-enclosed cytoplasmic organelles, which posses an acidic interior that contains many hydrolytic enzymes. Their major function is in the the degradation of macromolecules, which may be cellular or foreign in origin.
M J, Boyer, I F, Tannock
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Lysosomal Enzyme Abnormalities in Keratoconus
Archives of Ophthalmology, 1989We studied the lysosomal enzyme activities in corneas obtained from 12 patients with keratoconus. Three acid hydrolases--acid phosphatase, acid esterase, and acid lipase--were demonstrated by histochemical staining methods in the epithelium, stroma, and endothelium of corneas with keratoconus and normal human corneas.
S, Sawaguchi +3 more
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