Results 131 to 140 of about 239,873 (360)
Advanced Materials, EarlyView.Intrinsically disordered protein‐inspired nanovectors (IDP‐NVs) form stable nanocoacervates (NCs) with diverse biomacromolecules. In situ conformational changes confer stability and adaptability to NCs under dynamically changing physiological conditions.
Soyeong Jin +14 more
wiley +1 more source
Lysosomes and LAMPs as Autophagy Drivers of Drug Resistance in Colorectal Cancer
CellsColorectal cancer (CRC) is among the most malignant pathologies worldwide. A major factor contributing to the poor prognosis of neoplastic diseases is the development of drug resistance.
Tsvetomira Ivanova +3 more
doaj +1 more source
Dysregulation of of phospholipid-specific phagocytosis by B1 B cells in diet-induced obese mice [PDF]
, 2016 B1 B cells have received increasing attention recently due to their newly discovered phagocytic and microbicidal capabilities. Several studies have demonstrated that B1 cells can phagocytize polystyrene fluorescent particles, bacteria (Staphylococcus ...
Vo, Hung
core +1 more source
Biochimica et Biophysica Acta (BBA) - Molecular Cell Research, 2009 Gieselmann, Volkmar, Braulke, Thomas
openaire +3 more sources
Bacteria‐Responsive Nanostructured Drug Delivery Systems for Targeted Antimicrobial Therapy
Advanced Materials, EarlyView.Bacteria‐responsive nanocarriers are designed to release antimicrobials only in the presence of infection‐specific cues. This selective activation ensures drug release precisely at the site of infection, avoiding premature or indiscriminate release, and enhancing efficacy.
Guillermo Landa +3 more
wiley +1 more source
Size-dependent mechanism of cargo sorting during lysosome-phagosome fusion is controlled by Rab34 [PDF]
, 2012 Bahram Kasmapour +4 more
openalex +1 more source
Advanced Materials, EarlyView.Bioorthogonal chemistry was applied to intracellularly photoactivate Doxorubicin (Dox) using gold nanostars (AuNSt) and near‐infrared (NIR) light. Two prodrugs were used: one photoactivatable, masked with 2‐nitrobenzyl carbamate (proDox1) and another photolabile, masked with 2‐nitrobenzyl diol (proDox2), which was attached to the AuNSt surface.
Juan José Esteve‐Moreno +15 more
wiley +1 more source
Advanced Materials, EarlyView.An acid‐responsive polymeric micelle system based of aliphatic poly(carbonate)s with benzyl ketal side chains is designed for targeted immunodrug delivery. It can disassemble in endosomal environments, enabling site‐specific immunoactivation and enhanced biodegradability.
Adrian V. Hauck +16 more
wiley +1 more source
Advanced Materials, EarlyView.Photothermal nanodiamonds with quantum sensing capabilities generate lysosome‐confined hyperthermia, enabling simultaneous temperature and radical detection via diamond sensing. This localized thermal and oxidative stress drives pro‐inflammatory (M1) macrophage polarization, revealing a new strategy for precision immunomodulation through subcellular ...
Kaiqi Wu +11 more
wiley +1 more source
Multiphysics‐Driven Assembly of Biomimetic Vesicles
Advanced Materials, EarlyView.Artificial extracellular vesicles, derived from cell membranes, are manufactured using a multiphysics‐integrated microfluidic platform that combines nanoknife membrane rupture, herringbone chaotic mixing, and acoustothermal modulation. This standardizable workflow enables the predictable control of vesicle formation and therapeutic loading, while ...
Timofei Solodko +16 more
wiley +1 more source