Results 21 to 30 of about 155,219 (227)
Multifunctional Lysyl Oxidases
International Journal of Molecular Sciences, 2023 This Special Issue on lysyl oxidases, which are proteins derived from five related genes known as Lox, and Loxl1–Loxl4, brings together articles that reflect some of the diverse approaches and perspectives needed to better understand the biology of these multifunctional proteins [...]
openaire +2 more sources
Lysyl Oxidases in the Trabecular Meshwork [PDF]
Journal of Glaucoma, 2014 The mechanical properties of the extracellular matrix (ECM) play an important role in maintaining cellular function and overall tissue homeostasis. Emerging evidence suggests that biomechanical modifications of the ECM may be initiators and/or drivers of disease, exemplified by increased tissue stiffness.
Robert J, Wordinger, Abbot F, Clark
openaire +2 more sources
Prognostic implications of carboxyl-terminus of Hsc70 interacting protein and lysyl-oxidase expression in human breast cancer [PDF]
, 2010 This article has been made available through the Brunel Open Access Publishing Fund - Copyright @ 2010 Patani.Background: Ubiquitin modification of proteins influences cellular processes relevant to carcinogenesis.
Jiang, W +11 more
core +1 more source
Focus on Molecules: Lysyl oxidase [PDF]
Experimental Eye Research, 2012 1. StructureLysyl Oxidase (LOX, also called protein-lysine 6-oxidase)(Genbank accession numbers: Nucleotide NM_002317.5, ProteinNP_002308.2, EC 1.4.3.13) is one of the five LOX family members(LOX and LOX Like1-4). The human LOX gene is located onchromosome 5q23.2.
Anirudh, Sethi +2 more
openaire +2 more sources
Diagnostics, 2021 (1) Background: Lysyl oxidase (LOX) plays a dual role in carcinogenesis and studies show a higher risk of cancer in LOX G473A variants. The present study evaluated the pattern of LOX G473A polymorphism (rs1800449) and serum LOX levels in ovarian cancer ...
Suchitra Kumari +4 more
doaj +1 more source
LOXL2 (lysyl oxidase-like 2) [PDF]
, 2010 Review on LOXL2 (lysyl oxidase-like 2), with data on DNA, on the protein encoded, and where the gene is ...
SFT Fong +5 more
core +1 more source
A narrative review on serum biomarkers of cardiac fibrosis
Journal of the Practice of Cardiovascular Sciences, 2023 Myocardial fibrosis is the excessive deposition of extracellular matrix (ECM) proteins in the cardiac interstitium leading to pathological conditions of the heart.
Santoshi Kumari +3 more
doaj +1 more source
Origin and evolution of lysyl oxidases [PDF]
Scientific Reports, 2015 AbstractLysyl oxidases (LOX) are copper-dependent enzymes that oxidize primary amine substrates to reactive aldehydes. The best-studied role of LOX enzymes is the remodeling of the extracellular matrix (ECM) in animals by cross-linking collagens and elastin, although intracellular functions have been reported as well.
Xavier Grau-Bové +2 more
openaire +3 more sources
LOXL3 (lysyl oxidase-like 3) [PDF]
, 2009 Review on LOXL3 (lysyl oxidase-like 3), with data on DNA, on the protein encoded, and where the gene is ...
K Csiszar +3 more
core +1 more source
Molecular Insights Into Lysyl Oxidases in Cartilage Regeneration and Rejuvenation
Frontiers in Bioengineering and Biotechnology, 2020 Articular cartilage remains among the most difficult tissues to regenerate due to its poor self-repair capacity. The lysyl oxidase family (LOX; also termed as protein-lysine 6-oxidase), mainly consists of lysyl oxidase (LO) and lysyl oxidase-like 1-4 ...
Weiping Lin +3 more
doaj +1 more source