Results 31 to 40 of about 13,239 (158)
Frontiers in Chemistry, 2018 Accumulating evidence suggests an unequivocal role of lysyl oxidases as key players of tumor progression and metastasis, which renders this enzyme family highly attractive for targeted non-invasive functional imaging of tumors. Considering their function
Manuela Kuchar +15 more
doaj +1 more source
Site-specific expression of amine oxidases in breast cancer metastases
Tumor Biology, 2018 We aimed to evaluate the expression of amine oxidase-related proteins in metastatic breast cancer tissue and determine its clinical implication. A tissue microarray was constructed from a total of 126 metastatic breast tumors (31 bone metastases (24.6%),
Yoon Jin Cha, Woo Hee Jung, Ja Seung Koo
doaj +1 more source
Ibn Al-Haitham Journal for Pure and Applied Sciences, 2018 This study was aimed to determine bone formation markers (OST and BALP) and lysyl oxidase in diabetes and non-diabetes Iraqi acromegaly patients in addition to find the relationship among these parameters.
Eiman A. Abass +2 more
doaj +1 more source
PLoS ONE, 2023 The purpose of this study was to determine whether FABP1 and FAS regulate expression of collagen and its crosslinking via lysyl oxidase in isolated adipocytes from Zongdihua pigs.
Rong Yang +8 more
doaj +1 more source
Insights into the structure and dynamics of lysyl oxidase propeptide, a flexible protein with numerous partners [PDF]
, 2018 Lysyl oxidase (LOX) catalyzes the oxidative deamination of lysine and hydroxylysine residues in collagens and elastin, which is the first step of the cross-linking of these extracellular matrix proteins.
Duclos, Bertrand +6 more
core +4 more sources
Fibulin-4 is essential for maintaining arterial wall integrity in conduit but not muscular arteries [PDF]
, 2017 Homozygous or compound heterozygous mutations in fibulin-4 (FBLN4) lead to autosomal recessive cutis laxa type 1B (ARCL1B), a multisystem disorder characterized by significant cardiovascular abnormalities, including abnormal elastin assembly, arterial ...
Broekelmann, Thomas J +5 more
core +3 more sources
GWAS links variants in neuronal development and actin remodeling related loci with pseudoexfoliation syndrome without glaucoma [PDF]
, 2018 Pseudoexfoliation syndrome (PEXS) is an age-related elastosis, strongly associated with the development of secondary glaucoma. It is clearly suggested that PEXS has a genetic component, but this has not been extensively studied.
Bałabas, Aneta +8 more
core +1 more source
LOXL2 Inhibitors and Breast Cancer Progression
Antioxidants, 2021 LOX (lysyl oxidase) and lysyl oxidase like-1–4 (LOXL 1–4) are amine oxidases, which catalyze cross-linking reactions of elastin and collagen in the connective tissue.
Sandra Ferreira +3 more
doaj +1 more source
Nature Communications, 2023 To overcome chemotherapy resistance, novel strategies sensitizing cancer cells to chemotherapy are required. Here, we screen the lysyl-oxidase (LOX) family to clarify its contribution to chemotherapy resistance in liver cancer.
Meixiao Zhan +7 more
doaj +1 more source
Atlas of Genetics and Cytogenetics in Oncology and Haematology, 2011 Review on LOX (lysyl oxidase), with data on DNA, on the protein encoded, and where the gene is implicated.
Fong, SFT, Fong, KSK, Csiszar, K
openaire +2 more sources