Results 111 to 120 of about 44,822 (222)

Characterization of two lytic bacteriophages infecting carbapenem-resistant clinical Klebsiella pneumoniae in Dhaka, Bangladesh

Virus Research
Bacteriophages or bacteria infecting viruses are genetically diverse. Due to the emergence of antimicrobial-resistant bacteria, lytic bacteriophages are gaining enormous attention for treating superbug infections.
Nishat Tasnim Ananna, Tushar Ahmed Shishir, Akash Ahmed, Syed Muktadir Al Sium, Md Salman Shakil, Fahim Kabir Monjurul Haque, Md Hasanuzzaman   +6 more
doaj   +1 more source

Lambda-prophage induction modeled as a cooperative failure mode of lytic repression

, 2008
We analyze a system-level model for lytic repression of lambda-phage in E. coli using reliability theory, showing that the repressor circuit comprises 4 redundant components whose failure mode is prophage induction.
A. Arkin, A. Hill, G. Stent, Ido Golding, L. Gavrilov, M. Dutreix, M. Ptashne, Nicholas Chia, Nigel Goldenfeld, S. Luria   +9 more
core   +1 more source

Lytic Activity of Various Phage Cocktails on Multidrug-Resistant Bacteria

Clinical and Investigative Medicine, 2016
Purpose A bacteriophage is a virus that infects and replicates within a bacterium following the injection of phage genome into the bacterial cytoplasm. They are seen as a possible therapy for multi-drug-resistant strains of many bacteria. The aim of this study is to evaluate the lytic activity of the Pyo, Intesti and Fersisi bacteriophage cocktails on ...
I, Ozkan, E, Akturk, N, Yeshenkulov, S, Atmaca, N, Rahmanov, H I, Atabay   +5 more
openaire   +3 more sources

Genome sequence of Streptococcus mutans bacteriophage M102 [PDF]

, 2017
Bacteriophage M102 is a lytic phage specific for serotype c strains of Streptococcus mutans, a causative agent of dental caries. In this study, the complete genome sequence of M102 was determined.
van der Ploeg, J R.
core  

Phage Lytic Protein CHAPSH3b Encapsulated in Niosomes and Gelatine Films

Microorganisms
Antimicrobial resistance (AMR) has emerged as a global health challenge, sparking worldwide interest in exploring the antimicrobial potential of natural compounds as an alternative to conventional antibiotics. In recent years, one area of focus has been the utilization of bacteriophages and their derivative proteins. Specifically, phage lytic proteins,
Verdiana Marchianò, Ana Catarina Duarte, Seila Agún, Susana Luque, Ismael Marcet, Lucía Fernández, María Matos, Mª del Carmen Blanco, Pilar García, Gemma Gutiérrez   +9 more
openaire   +5 more sources

Control of lysogeny and antiphage defense by a prophage-encoded kinase-phosphatase module

Nature Communications
The filamentous ‘Pf’ bacteriophages of Pseudomonas aeruginosa play roles in biofilm formation and virulence, but mechanisms governing Pf prophage activation in biofilms are unclear.
Yunxue Guo, Kaihao Tang, Brandon Sit, Jiayu Gu, Ran Chen, Xinqi Shao, Shituan Lin, Zixian Huang, Zhaolong Nie, Jianzhong Lin, Xiaoxiao Liu, Weiquan Wang, Xinyu Gao, Tianlang Liu, Fei Liu, Hongbo R. Luo, Matthew K. Waldor, Xiaoxue Wang   +17 more
doaj   +1 more source

“Sichuanvirus”, a novel bacteriophage viral genus, able to lyse carbapenem-resistant Klebsiella pneumoniae

BMC Microbiology
Background Carbapenem-resistant Klebsiella pneumoniae (CRKP) is a severe threat for human health and urgently needs new therapeutic approaches. Lytic bacteriophages (phages) are promising clinically viable therapeutic options against CRKP.
Juan Li, Qingqing Fang, Huan Luo, Yan Feng, Yu Feng, Zhiyong Zong   +5 more
doaj   +1 more source

Genomic analysis and characterization of lytic bacteriophages that target antimicrobial resistant Escherichia coli in Addis Ababa, Ethiopia

Heliyon
The emergence of antibiotic resistance in E. coli strains has sparked a fervent investigation of alternative therapies, such as the use of lytic bacteriophages.
Tamirat Salile Sada, Dawit Hailu Alemayehu, Kalkidan Melaku Tafese, Tesfaye Sisay Tessema   +3 more
doaj   +1 more source

Experimental phage therapy of burn wound infection : difficult first steps [PDF]

, 2014
Antibiotic resistance has become a major public health problem and the antibiotics pipeline is running dry. Bacteriophages (phages) may offer an ‘innovative’ means of infection treatment, which can be combined or alternated with antibiotic therapy and ...
De Vos, Daniel, Jennes, Serge, Lavigne, Rob, Merabishvili, Maia, Pirnay, Jean Paul, Rose, Thomas, Vaneechoutte, Mario, Verbeken, Gilbert, Zizi, Martin   +8 more
core  

Lytic bacteriophages induce the secretion of antiviral and proinflammatory cytokines from human respiratory epithelial cells.

PLoS Biology
Phage therapy is a therapeutic approach to treat multidrug-resistant (MDR) infections that employs lytic bacteriophages (phages) to eliminate bacteria. Despite the abundant evidence for its success as an antimicrobial in Eastern Europe, there is scarce ...
Paula F Zamora, Thomas G Reidy, Catherine R Armbruster, Ming Sun, Daria Van Tyne, Paul E Turner, Jonathan L Koff, Jennifer M Bomberger   +7 more
doaj   +1 more source