Results 91 to 100 of about 30,001 (226)

Genomic characterization and pre-clinical evaluation of a new polyvalent lytic Loughborough phage

Applied Microbiology and Biotechnology
Carbapenem-resistant Acinetobacter baumannii (CRAB) has become a critical concern that necessitates the development of novel antimicrobial approaches. One of the most promising innovative approaches for combating CRAB infections is using effective and ...
Mahmoud M. Sherif, Neveen A. Abdelaziz, Sarra E. Saleh, Khaled M. Aboshanab   +3 more
doaj   +1 more source

Lytic Activity of Isolated Phage from Milk Against Extended-Spectrum Beta-Lactamase Escherichia coli

Journal of Mazandaran University of Medical Sciences, 2021
Background and purpose: Escherichia coli (E.coli) is the most common cause of urinary tract infection. The treatment strategy has been hampered by the emergence of broad-spectrum beta-lactamase-producing E.coli and its resistance to most antibiotics ...
Golnar Rahimzadeh, Mohammad Sadegh Rezai, Elaheh Ahmadi   +2 more
doaj  

Bacteriophages in the Rhizosphere: Roles in Nutrient Cycling, Bacterial Community Structure, and Animal‐Mediated Dispersal

MicrobiologyOpen, Volume 15, Issue 3, June 2026.
This review discusses bacteriophages' roles in soil ecosystems, highlighting their impact on nutrient cycling, plant health, and soil remediation, as well as animal‐mediated phage dispersal mechanisms. Overall, while bacteriophages have potential biotechnological applications, their negative effects on microbial functions and nutrient cycling highlight
Majid Komijani, Hassan Maddahi, Marzieh Rezaei, Mohammad Hussein Abnosi, Abdullah Khalaf Ahmed   +4 more
wiley   +1 more source

Pathogenic Mechanisms of V. vulnificus and Its Role in the Development of Sepsis

MicrobiologyOpen, Volume 15, Issue 3, June 2026.
Sorafenib attenuates urethral scar formation by inhibiting β‐catenin signaling in fibroblasts, which downregulates the SLC7A11/GPX4 antioxidant axis and triggers ferroptosis. This β‐catenin–ferroptosis coupling effectively suppresses fibrogenesis, highlighting sorafenib as a promising drug‐repurposing candidate for urethral stricture.
Zhongying Yu, Xianzhong Zhu, Shijie Tang, Shubo Yang, Jinyu Li, Lianzhong Luo, Yan Tan, Jun Yin   +7 more
wiley   +1 more source

Isolation and Characterization of Lytic Coliphages from Sewage Water

, 2017
The goal of this study was to isolate and characterize phages that might be used in transport and treatment of potential E.coli pathogen in water sources.
PS Harikumar, S. Murugan, S Murugan, P.S. Harikumar, P.U. Megha, PU Megha   +5 more
core   +1 more source

Lytic gene expression in the temperate bacteriophage GIL01 is activated by a phage-encoded LexA homologue [PDF]

, 2018
The GIL01 bacteriophage is a temperate phage that infects the insect pathogen Bacillus thuringiensis. During the lytic cycle, phage gene transcription is initiated from three promoters: P1 and P2, which control the expression of the early phage genes ...
Browning, Douglas F, Pavlin, Anja, Salas, Margarita, Browning, Douglas F., Butala, Matej, Fornelos, Nadine, Podlesek, Zdravko, Hodnik, Vesna   +7 more
core   +1 more source

Human Gut Phageome Analysis Uncovers Thousands of Highly Modular Endolysins

MicrobiologyOpen, Volume 15, Issue 3, June 2026.
Analysis of 9141 human gut metagenomes identified 15,267 phage genomes and 3794 highly modular endolysins. The recovered endolysins showed remarkable catalytic and cell wall–binding domain diversity, highlighting the gut phageome as a rich source of novel enzybiotics with therapeutic potential against multidrug‐resistant bacteria.
Raphael Kabir Niloy, Nurnabi Azad Jewel, Daniyal Karim, Mohimenul Haque Rolin, Tahsin Khan, Arzuba Akter, Shakhinur Islam Mondal   +6 more
wiley   +1 more source

Structure of colitis phage lytic enzyme gene

, 1990
A sequence of 163 amino acids was derived from the nucleotide sequence of a DNA fragment bearing the colitis phage lytic enzyme gene. The molecular weight, basicity and the sequence of the three N-terminal amino acids agreed with those of the phage lytic
Padayatty, J. D., Gupta, A.
core   +1 more source

Lung Microbiome Diversity, Infection Dynamics, and Microbe‐Mediated Cross‐Protection

MicrobiologyOpen, Volume 15, Issue 3, June 2026.
The protective role of the lung microbiome in maintaining respiratory health by promoting immune homeostasis, pathogen exclusion, and barrier integrity. Diverse microbial communities regulate immune maturation, enhance epithelial defenses, and contribute to antiviral responses, collectively preventing pathogen colonization and sustaining a balanced ...
Sana Arooj, Akmal Zubair, Syeda Zaira Batool, Granaz Niaz, Muhammad Ali, Yasir Waheed, Eman Ramadan Elsharkawy, Naila Afghan   +7 more
wiley   +1 more source

Predator–Microbe Dynamics Inform Strategies for Robust Synthetic Community Assembly

Environmental Microbiology, Volume 28, Issue 6, June 2026.
This Review introduces ecological principles of predator–prey interactions as a new dimension in SynCom design. By linking microbial defence traits, encounter dynamics, and adaptive buffering, it outlines a framework for constructing predator‐resistant synthetic communities with enhanced resilience, stability, and functional performance under natural ...
Eleonora Egidi, Uffe N. Nielsen
wiley   +1 more source