Results 181 to 190 of about 108,965 (216)

Diagnostic and Therapeutic Applications of Lytic Phages

Analytical Letters, 2003
The ability of lytic phages to rapidly kill and lyse infected bacteria, the specificity of phages for particular bacteria, and the ability of phages to increase in number during the infection process make phages excellent potential diagnostic and therapeutic agents for fighting bacterial disease.
Rosemonde Mandeville, Mansel Griffiths, Larry Goodridge, Lynn McIntyre, T. Toney Ilenchuk   +4 more
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Implications of lytic phage infections inducing persistence

Current Opinion in Microbiology
Phage therapy holds much promise as an alternative to antibiotics for fighting infection. However, this approach is no panacea as recent results show that a small fraction of cells survives lytic phage infection due to both dormancy (i.e. formation of persister cells) and resistance (genetic change).
Viviana, Sanchez-Torres, Joy, Kirigo, Thomas K, Wood   +2 more
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Description of a new phage lytic for several Brucella species

Journal of Biological Standardization, 1976
A new brucella-phage was isolated from a batch of Tbilisi (Tb) phage prepared 5 years previously. Unlike Tb phage this phage strain, designated MC/75, replicated with high efficiency in Brucella abortus and Br. suis and to a less extent in Br. neotomae cultures. It did not replicate in cultures of Br.
M J, Corbel, E L, Thomas
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Structure and regulation of the lytic replicon of phage P1

Journal of Molecular Biology, 1989
Three replicons, R, L and P1dR, have been previously identified in bacteriophage P1, but only the R (or plasmid) replicon has been functionally and structurally characterized. Evidence is provided here that the L-replicon is the principal replicon used for DNA replication during the lytic cycle. The L-replicon (exclusive of its promoter) is shown to be
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Bactria and Lytic Phage Coexistence in a Chemostat with Periodic Nutrient Supply

Bulletin of Mathematical Biology, 2013
The dynamics of bacteria and bacteriophage coexistence was examined in a chemostat in which the externally driven supply of nutrient for bacteria, and washout rate oscillates periodically. The proposed mathematical model for three interacting variables, bacteria, phage, and nutrient, consists of 3 differential equations with time delay, due to the ...
Aviram, Ira, Rabinovitch, Avinoam
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New lytic and new temperate Staphylococcus hyicus phages

Virus Genes
A novel lytic phage with a broad host range was isolated from pig faeces and the complete genome was subsequently sequenced. The phage was found to lyse Staphylococcus hyicus, S. pseudintermedius, S. schleiferi and S. warneri, generating approximately 27 PFU per infected S. hyicus cell.
Karel Petrzik, Lucie Sovová
openaire   +2 more sources

Optimization of lytic phage manufacturing in bioreactor using monolithic supports

Journal of Separation Science, 2011
AbstractA process for manufacturing large quantities of lytic bacteriophages was developed. Determination of cultivation termination was found to be essential to achieve high phage quantity and purity. When optimal cultivation termination is missed, phage fraction was found to be highly contaminated with deoxyribonucleic acid released from Escherichia ...
Franc, Smrekar, Mateja, Ciringer, Janez, Jančar, Peter, Raspor, Aleš, Štrancar, Aleš, Podgornik   +5 more
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Formation of the Repressor for Lytic Phage Development after Infection of Salmonella Typhimurium by Phage P22

Nature, 1962
Formation of the Repressor for Lytic Phage Development after Infection of Salmonella Typhimurium by Phage ...
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Structure of colitis phage lytic enzyme gene.

Biochemistry international, 1991
A sequence of 163 amino acids was derived from the nucleotide sequence of a DNA fragment bearing the colitis phage lytic enzyme gene. The molecular weight, basicity and the sequence of the three N-terminal amino acids agreed with those of the phage lytic enzyme.
A, Gupta, J D, Padayatty
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[Lytic phages and prophages of Streptococcus suis--a review].

Wei sheng wu xue bao = Acta microbiologica Sinica, 2015
Streptococcus suis (S. suis) is an important zoonosis and pathogen that can carry prophages. In this review, we focus on the recent advances in our understanding of lytic phage and lysogenic phage of S. suis, including the morphology of S. suis lytic phage, the functions of lysin and terminase large subunit encoded by S.
Fang, Tang, Chengping, Lu
openaire   +1 more source