Results 111 to 120 of about 4,476 (193)

Influence of microbiota on the growth and gene expression of Clostridioides difficile in an in vitro coculture model

open access: yesMicrobiologyOpen, Volume 13, Issue 5, October 2024.
The presence of microbiota did not affect the growth of Clostridioides difficile in this study. However, it did influence the expression of C. difficile genes related to sporulation, germination, and virulence, which are crucial for the transmission of the pathogen. In the presence of microbiota, C.
Elisa Martinez   +4 more
wiley   +1 more source

The Pathogenic Neisseria Use a Streamlined Set of Peptidoglycan Degradation Proteins for Peptidoglycan Remodeling, Recycling, and Toxic Fragment Release

open access: yesFrontiers in Microbiology, 2019
Neisseria gonorrhoeae and Neisseria meningitidis release peptidoglycan (PG) fragments from the cell as the bacteria grow. For N. gonorrhoeae these PG fragments are known to cause damage to human Fallopian tube tissue in organ culture that mimics the ...
Ryan E. Schaub, Joseph P. Dillard
doaj   +1 more source

A metagenomic survey of the fecal microbiome of the African savanna elephant (Loxodonta africana)

open access: yesAnimal Genetics, Volume 55, Issue 4, Page 621-643, August 2024.
Abstract The African savanna elephant (Loxodonta africana) is the largest terrestrial animal on Earth and is found primarily in Southern and Eastern Africa. It is a hindgut, colonic fermenter and subsists on a diet of raw plant materials found in its grazing area.
Louis Lategan du Preez   +5 more
wiley   +1 more source

Structural insights into MltB from Acinetobacter baumannii: a conserved catalytic tunnel with unique domain arrangement

open access: yesIUCrJ
Lytic transglycosylases (LTs) play a central role in bacterial cell wall remodeling by cleaving the β-1,4-glycosidic bond in peptidoglycan via a non-hydrolytic mechanism, producing 1,6-anhydroMurNAc termini crucial for recycling and signaling. Among LTs,
Hyunseok Jang   +3 more
doaj   +1 more source

Characterization of the Nonconserved hpaB-hrpF Region in the hrp Pathogenicity Island from Xanthomonas campestris pv. vesicatoria

open access: yesMolecular Plant-Microbe Interactions, 2007
The interaction of the gram-negative phytopathogenic bacterium Xanthomonas campestris pv. vesicatoria with its host plants pepper and tomato is mediated by a type III secretion (T3S) system that translocates bacterial effector proteins into the plant ...
Daniela Büttner   +3 more
doaj   +1 more source

Cleavage of an engulfment peptidoglycan hydrolase by a sporulation signature protease in Clostridioides difficile

open access: yesMolecular Microbiology, Volume 122, Issue 2, Page 213-229, August 2024.
Model for the cleavage of SpoIIP by SpoIVB2 during sporulation in Clostridioides difficile. Soon after engulfment completion, SpoIVB2 cleaves SpoIIP, part of the engulfasome complex, to generate the SpoIIPc form. The function of SpoIVB2 is required for synthesis of the cortex layer which takes place across the outer forespore membrane.
Diogo Martins   +11 more
wiley   +1 more source

Crystal structure of the PepSY-containing domain of the YpeB protein involved in germination of bacillus spores. [PDF]

open access: yes, 2015
The crystal structure of the C-terminal domain of the Bacillus megaterium YpeB protein has been solved by X-ray crystallography to 1.80-Å resolution. The full-length protein is essential in stabilising the SleB cortex lytic enzyme in Bacillus spores, and
Chirgadze, Dimitri Y   +2 more
core   +1 more source

Determinants in the phage life cycle: The dynamic nature of ssDNA phage FLiP and host interactions under varying environmental conditions and growth phases

open access: yesEnvironmental Microbiology, Volume 26, Issue 7, July 2024.
The interactions between the lipid‐containing ssDNA phage FLiP and its three Flavobacterium hosts are influenced by factors such as the host strain and culture conditions, including temperature and bacterial growth phase. Abstract The influence of environmental factors on the interactions between phages and bacteria, particularly single‐stranded DNA ...
Kati Mäkelä   +2 more
wiley   +1 more source

MtrR Regulates a Major Lytic Transglycosylase (ltgA) Responsible for Peptidoglycan-Derived Cytotoxin Release and Autolysis in Neisseria gonorrhoeae

open access: yesMicroorganisms
The multiple-transferable resistance protein (MtrR) is a transcriptional repressor of the mtrCDE-encoded drug efflux pump and Type IV pilus biosynthesis (pilM), and an activator of penicillin-binding protein 1 (ponA) expression in Neisseria gonorrhoeae ...
Alaa I. Telchy   +6 more
doaj   +1 more source

Diversity and Distribution of a Novel Genus of Hyperthermophilic Aquificae Viruses Encoding a Proof-Reading Family-A DNA Polymerase

open access: yesFrontiers in Microbiology, 2020
Despite the high abundance of Aquificae in many geothermal systems, these bacteria are difficult to culture and no viruses infecting members of this phylum have been isolated. Here, we describe the complete, circular dsDNA Uncultivated Virus Genome (UViG)
Marike Palmer   +15 more
doaj   +1 more source

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