Results 51 to 60 of about 1,003,741 (265)

Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis

Molecular Oncology, EarlyView.
This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht, Sameer Gupta, Amrita Chaurasia, Manisha Sachan   +3 more
wiley   +1 more source

Pengembangan Model Implementasi M-Pembelajaran untuk Mahasiswa Pendidikan Guru di Indonesia

Inovasi Kurikulum, 2020
Tujuan dari penelitian ini adalah untuk mengembangkan model implementasi M-Learning berdasarkan kegiatan pembelajaran dalam program pendidikan guru.
Muhamad Asra, Taufik Yogaswara, Nanda Khaerunnisa Syafitri   +2 more
doaj   +1 more source

M-Learning in the Middle East [PDF]

, 2015
The introduction of e-learning in higher education has brought radical changes in the way undergraduate and postgraduate programmes are designed and delivered. University students now have access to their courses anytime, anywhere, which makes e-learning and m-learning popular and fashionable among university students globally.
Marinakou, Evangelia, Giousmpasoglou, Charalampos   +1 more
openaire   +1 more source

Hoarding Content in M-Learning Context [PDF]

Third IEEE International Conference on Pervasive Computing and Communications Workshops, 2005
With the advances in mobile technologies is now possible to support learners and teachers activities on the move. We analyzed the functionalities that should be provided by a general mobile learning platform and identified a problem that is weakly studied, namely support for offline usage of learning material, called hoarding.
Trifonova, Anna Plamenova, Ronchetti, Marco   +1 more
openaire   +2 more sources

Patient therapy outcome modeling in cancer organoids is improved by cancer‐associated fibroblasts and organoid assembly convolution

Molecular Oncology, EarlyView.
Patient‐derived organoids (PDOs) from pancreatic, colorectal, and gastric cancers were used to evaluate standard and experimental therapies. Incorporating cancer‐associated fibroblasts (CAFs) into organoid cultures improved patient therapy outcome prediction.
Marcin Grochowski, Liudmyla Dolinchuk, Michał Jerzak, Albert Gandurski, Tomasz Grochowski, Weronika Wojtyś, Maciej Zadrożny, Wojciech Kaźmierczak, Małgorzata Lenarcik, Marta Matejak‐Górska, Radosław Samsel, Tomasz Olesiński, Dawid Walerych   +12 more
wiley   +1 more source

E-Learning Design for Older Adults in the United States

Social Sciences
As global populations age, there is an urgent need to address the unique learning requirements of older adults in the context of e-learning. This study builds upon prior work to investigate the connections between older adults’ cognitive profiles ...
Shelby L. Sharpe, Susan A. Elwood
doaj   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

Molecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim, Hwiyeong Lee, Jin Hong, Daechan Park   +3 more
wiley   +1 more source

M-Learning for Elderlies: A Case Study [PDF]

, 2012
In this article a case study about m-learning for elderlies using mobile devices is presented. The study focuses on a practical study about language learning for elderly students that attend classes in the so-called Inter-university program for Elderly People.
Fernando De la Prieta, Antonia Macarro, Amparo Jiménez, Amparo Casado, Kasper Hallenborg, Juan Francisco de Paz, Sara Rodríguez 0001, Javier Bajo   +7 more
openaire   +2 more sources

Applicability of mitotic figure counting by deep learning: a development and pan‐cancer validation study

FEBS Open Bio, EarlyView.
In this study, we developed a deep learning method for mitotic figure counting in H&E‐stained whole‐slide images and evaluated its prognostic impact in 13 external validation cohorts from seven different cancer types. Patients with more mitotic figures per mm2 had significantly worse patient outcome in all the studied cancer types except colorectal ...
Joakim Kalsnes, Maria X. Isaksen, Frida Julbø, Manohar Pradhan, Andreas Kleppe, Sepp De Raedt, Ole‐Johan Skrede, Turid Torheim, John Arne Nesheim, Hans Martin Mohn, Hanne A. Askautrud, Karolina Cyll, Wanja Kildal, Emma Rewcastle, Melinda Lillesand, Vebjørn Kvikstad, Emiel Janssen, Robert Jones, Odd Terje Brustugun, Bjørn Brennhovd, Erik Skaaheim Haug, Lill‐Tove Rasmussen Busund, Elin Richardsen, Sigve Andersen, Tom Dønnem, Kristina Lindemann, Gunnar Kristensen, Neil A. Shepherd, Marco Novelli, Knut Liestøl, David Kerr, Håvard E. Danielsen, Tarjei S. Hveem   +32 more
wiley   +1 more source

Rapid screening of staphylokinase protein variants using an unpurified cell‐free expression system

FEBS Open Bio, EarlyView.
An unpurified cell‐free protein synthesis (CFPS) platform enables rapid functional screening of staphylokinase variants. Direct plasminogen‐activation assays performed in microplate format provide real‐time activity readouts, allowing rapid identification and ranking of variants with improved or reduced fibrinolytic activity without protein ...
Maria Tomková, Veronika Hovanová, Jiri Damborsky, Erik Sedlák   +3 more
wiley   +1 more source