Results 111 to 120 of about 1,572,263 (313)
Fuzzy Approximate Solution of Positive Fully Fuzzy Linear Matrix Equations
Journal of Applied Mathematics, 2013 The fuzzy matrix equations A~⊗X~⊗B~=C~ in which A~, B~, and C~ are m×m, n×n, and m×n nonnegative LR fuzzy numbers matrices, respectively, are investigated.
Xiaobin Guo, Dequan Shang
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On regular splittings of an M-matrix
Linear Algebra and its Applications, 1989 Some results on regular splittings of M-matrices are proved. The study is motivated by a recent work of \textit{H. Schneider} [ibid. 58, 407-424 (1984; Zbl 0561.65020)]. It is shown, first, that if A is a nonsingular M-matrix and \(A=M-N\) is a regular splitting then this splitting is a graph compatible one, and if A is just an M-matrix but \(A=M-N ...
openaire +2 more sources
Molecular Oncology, EarlyView.Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz +15 more
wiley +1 more source
Molecular Oncology, EarlyView.HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto +13 more
wiley +1 more source
Molecular Oncology, EarlyView.Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source
Molecular Oncology, EarlyView.Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad +12 more
wiley +1 more source
Oncostatin M-Induced Matrix Metalloproteinase and Tissue Inhibitor of Metalloproteinase-3 Genes Expression in Chondrocytes Requires Janus Kinase/STAT Signaling Pathway [PDF]
, 2001 Wenqing Li +2 more
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Strength through diversity: how cancers thrive when clones cooperate
Molecular Oncology, EarlyView.Intratumor heterogeneity can offer direct benefits to the tumor through cooperation between different clones. In this review, Kuiken et al. discuss existing evidence for clonal cooperativity to identify overarching principles, and highlight how novel technological developments could address remaining open questions.
Marije C. Kuiken +3 more
wiley +1 more source
Multiplicative maps on generalized \(n\)-matrix rings
CuboLet \(\mathfrak{R}\) and \(\mathfrak{R}'\) be two associative rings (not necessarily with identity elements). A bijective map \(\varphi\) of \(\mathfrak{R}\) onto \(\mathfrak{R}'\) is called an \textit{\(m\)-multiplicative isomorphism} if {\(\varphi (x_ ...
Aisha Jabeen, Bruno L. M. Ferreira
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Stability of one-step and linear multistep methods - a matrix technique approach
Electronic Journal of Qualitative Theory of Differential Equations, 2016 We investigate the stability of one-step and linear multistep methods from a new direction. Our aim is to modify the long and technical proof which is consequently omitted in almost every textbook and make it user-friendly.
Miklós Emil Mincsovics
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