Results 71 to 80 of about 1,396,823 (294)

Adverse prognosis gene expression patterns in metastatic castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
We aggregated a cohort of 1012 mCRPC tissue samples from 769 patients and investigated the association of gene expression‐based pathways with clinical outcomes. Loss of AR signaling, high proliferation, and a glycolytic phenotype were independently prognostic for poor outcomes, and an adverse transcriptional feature score incorporating these pathways ...
Marina N. Sharifi, Eric Feng, Nicholas R. Rydzewski, Amy K. Taylor, Jamie M. Sperger, Yue Shi, Kyle T. Helzer, Matthew L. Bootsma, Viridiana Carreno, Alex H. Chang, Luke A. Nunamaker, Grace C. Blitzer, Tianfu Andy Shang, Aishwarya Subramanian, Anders Bjartell, Andreas Josefsson, Pernilla Wikström, Emily Feng, Manish Kohli, Rendong Yang, Scott M. Dehm, Eric J. Small, Rahul Aggarwal, David A. Quigley, Joshua M. Lang, Shuang G. Zhao, Martin Sjöström   +26 more
wiley   +1 more source

Acceptability of the R21/Matrix-M malaria vaccine alongside existing malaria interventions in the trial context

BMJ Global Health
Background The R21/Matrix-M malaria vaccine has been shown to provide high protective efficacy against malaria in a phase III trial, and has been recommended for use by WHO. The vaccine will soon be deployed at scale in sub-Saharan Africa.
Jayne Webster, Brian Greenwood, Daniel Chandramohan, Alassane Dicko, Issaka Sagara, Djibrilla Issiaka, Adrian VS Hill, Halimatou Diawara, Fatoumata Koita, Seydou Traoré, Jane Grant, Mehreen Datoo, Mala Sylla, Abdrahmane Boncane Dicko   +13 more
doaj   +1 more source

Generalized AOR Algorithms for Linear Complementarity Problem

Journal of Algorithms & Computational Technology, 2007
In this paper, we propose a class of generalized accelerated overrelaxation (GAOR) methods, in which one special case reduces to the generalized successive overrelaxation(GSOR) methods, for solving a linear complementarity problem LCP ( M, q ...
Dongjin Yuan, Hui Zhang
doaj   +1 more source

Transcriptome‐wide analysis of circRNA and RBP profiles and their molecular relevance for GBM

Molecular Oncology, EarlyView.
CircRNAs are differentially expressed in glioblastoma primary tumors and might serve as therapeutic targets and diagnostic markers. The investigation of circRNA and RNA‐binding proteins (RBPs) interactions shows that distinct RBPs play a role in circRNA biogenesis and function.
Julia Latowska‐Łysiak, Żaneta Zarębska, Marcin P. Sajek, Adriana Grabowska, Alessia Buratin, Paweł Głodowicz, Julia O. Misiorek, Konrad Kuczyński, Stefania Bortoluzzi, Marek Żywicki, Jan G. Kosiński, Agnieszka Rybak‐Wolf, Rafał Piestrzeniewicz, Anna M. Barciszewska, Katarzyna Rolle   +14 more
wiley   +1 more source

Precipitation of M23C6 Secondary Carbide Particles in Fe-Cr-Mn-C Alloy during Heat Treatment Process

Metals, 2020
The initial as-cast microstructure of high-chromium white cast iron (2.08% C, 12.1% Cr), including austenitic dendrites in a matrix of a eutectic mixture of austenite and M7C3 carbides.
Nguyen Thi Hoang Oanh, Nguyen Hoang Viet   +1 more
doaj   +1 more source

Elucidating prognostic significance of purine metabolism in colorectal cancer through integrating data from transcriptomic, immunohistochemical, and single‐cell RNA sequencing analysis

Molecular Oncology, EarlyView.
Low expression of five purine metabolism‐related genes (ADSL, APRT, ADCY3, NME3, NME6) was correlated with poor survival in colorectal cancer. Immunohistochemistry analysis showed that low NME3 (early stage) and low ADSL/NME6 (late stage) levels were associated with high risk.
Sungyeon Kim, Myunghee Kang, Soyeon Jeong, Jisup Kim, Kyoung Oh Kim, Won‐Suk Lee, Jeong‐Heum Baek, Jung Ho Kim, Seungyoon Nam   +8 more
wiley   +1 more source

Exact lattice bosonization of finite N matrix quantum mechanics and c = 1

Journal of High Energy Physics
We describe a new exact lattice bosonization of matrix quantum mechanics (equivalently of non-relativistic fermions) that is valid for arbitrary rank N of the matrix.
Gautam Mandal, Ajay Mohan
doaj   +1 more source

Matrix Pencil Optimal Iterative Algorithms and Restarted Versions for Linear Matrix Equation and Pseudoinverse

Mathematics
We derive a double-optimal iterative algorithm (DOIA) in an m-degree matrix pencil Krylov subspace to solve a rectangular linear matrix equation. Expressing the iterative solution in a matrix pencil and using two optimization techniques, we determine the
Chein-Shan Liu, Chung-Lun Kuo, Chih-Wen Chang   +2 more
doaj   +1 more source

Exploration of heterogeneity and recurrence signatures in hepatocellular carcinoma

Molecular Oncology, EarlyView.
This study leveraged public datasets and integrative bioinformatic analysis to dissect malignant cell heterogeneity between relapsed and primary HCC, focusing on intercellular communication, differentiation status, metabolic activity, and transcriptomic profiles.
Wen‐Jing Wu, Jianchao Wang, Fuqing Chen, Xuefeng Wang, Bin Lan, Ruyi Fu, Hong Wen, Fangfang Chen, Wei Hong, Tian‐Yu Tang, Ying He, Gang Chen, Jianyin Zhou, Hai‐Long Piao, Di Chen, Shu‐Yong Lin   +15 more
wiley   +1 more source

Fuzzy Symmetric Solutions of Fuzzy Matrix Equations

Advances in Fuzzy Systems, 2012
The fuzzy symmetric solution of fuzzy matrix equation AX˜=B˜, in which A is a crisp m×m nonsingular matrix and B˜ is an m×n fuzzy numbers matrix with nonzero spreads, is investigated.
Xiaobin Guo, Dequan Shang
doaj   +1 more source