Results 11 to 20 of about 709,638 (304)
Stopping Tuberculosis at the Gate: The Role of M. tuberculosis Adhesins in Infection and Intervention [PDF]
VaccinesThe global burden of tuberculosis (TB), exacerbated by the rise of drug-resistant Mycobacterium tuberculosis (M. tuberculosis), underscores the need for alternative intervention strategies. One promising approach is to block the infection at its earliest stage—bacterial adhesion to host cells—thereby preventing colonization and transmission without ...
Haoyan Yang +7 more
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M. tuberculosis: immunology and vaccination [PDF]
European Respiratory Journal, 2001 Tuberculosis is increasing. Current treatment regimens require at least 6 months, because latent or stationary phase organisms are difficult to kill. Such regimens do not achieve full compliance, and “directly observed therapy short course” (DOTS) is having less impact than expected.
G A, Rook, G, Seah, A, Ustianowski
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Immunogenic Activity of Lipids of M. tuberculosis [PDF]
Nature, 1965 LIPIDS of mycobacteria are known to be immunogenically active components of tubercle bacilli1. First of all, it was surprising that mycobacteria contain lipids up to 35 per cent of their dry weight2. This fact did not escape the notice of immunologists.
B, Stöss, R, Herrmann
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Role of metal-dependent regulation of ESX-3 secretion in intracellular survival of Mycobacterium tuberculosis [PDF]
, 2016 More people die every year from Mycobacterium tuberculosis infection than from infection by any other bacterial pathogen. Type VII secretion systems (T7SS) are used by both environmental and pathogenic mycobacteria to secrete proteins across their ...
Philips, Jennifer A +5 more
core +2 more sources
Эпидемиология и вакцинопрофилактика, 2020 Relevance. The spread of the epidemic and resistant Mycobacterium tuberculosis genotypes presents a serious threat to the implementation of the national tuberculosis control program in Russia.
O. A. Pasechnik +5 more
doaj +1 more source
Mycobacterium tuberculosis type VII secretion system effectors differentially impact the ESCRT endomembrane damage response [PDF]
, 2018 Mycobacterium tuberculosis causes tuberculosis, which kills more people than any other infection. M. tuberculosis grows in macrophages, cells that specialize in engulfing and degrading microorganisms.
Hanson, Phyllis I +7 more
core +2 more sources
Туберкулез и болезни лёгких, 2017 Based on real-time allele-specific polymerase chain reaction, the ranges of potential mutations in codons of 306 and 405 of the embBgene in Mycobacterium tuberculosis associated with resistance to ethambutol were investigated.
Yu. S. Аlyapkinа +5 more
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The population structure of Beijing family of Mycobacterium tuberculosis in Western Siberia
Туберкулез и болезни лёгких, 2020 The objective: to study the structure of Beijing genotype family of Mycobacterium tuberculosis in Omsk Region, Western Siberia.Subjects and methods: 325 strains of M. tuberculosis were studied, all of them were isolated from tuberculosis patients in Omsk
A. A. Vyazovaya +3 more
doaj +1 more source
Comparative characteristics of tuberculous pleurisy depending on HIV status
Туберкулез и болезни лёгких, 2016 Goal of the study: to study specific manifestations of tuberculous pleurisy in HIV patients, to evaluate the efficiency of video-assisted thoracoscopy when diagnosing tuberculous pleurisy in case of different HIV status of the patients.Materials and ...
E. V. Korzh, D. S. Miroshnichenko
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Tuberculosis diagnostics and biomarkers: needs, challenges, recent advances, and opportunities [PDF]
, 2012 Tuberculosis is unique among the major infectious diseases in that it lacks accurate rapid point-of-care diagnostic tests. Failure to control the spread of tuberculosis is largely due to our inability to detect and treat all infectious cases of pulmonary
Alexandre Harari +118 more
core +2 more sources