Results 41 to 50 of about 378,588 (317)

Molecular identification and infection pathology of Mycobacterium spp. in captive wild animals in Pakistan

Journal of Infection in Developing Countries, 2023
Introduction: Animal tuberculosis is an infectious, chronic, granulomatous, and debilitating disease affecting animals as well as humans. However, in recent decades, there have been many endemic geographic localities where animal tuberculosis has been ...
Komal Akhtar, Ishtiaq Ahmed, Muhammad Yasin Tipu, Tahir Yaqub, Muhammad Shahid, Aziz ur Rehman, Muhammad Zishan Ahmad, Ammar Ghani, Aman Ullah Khan, Adeem Rehman Rafie, Muhammad Kamran Rafique, Muhammad Saadullah, Muhammad Kashif, Asim Aslam   +13 more
doaj   +1 more source

Multidrug-resistant tuberculosis. [PDF]

, 2008
BACKGROUND: With almost 9 million new cases each year, tuberculosis remains one of the most feared diseases on the planet. Led by the STOP-TB Partnership and WHO, recent efforts to combat the disease have made considerable progress in a number of ...
Zager, Ellen M, McNerney, Ruth
core   +1 more source

Spinal Cord Infarction Versus Idiopathic Transverse Myelitis: Clinical, Radiological, and Functional Insights From a Retrospective Cohort Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Introduction Spinal cord infarction (SCI) is a rare but devastating myelopathy, characterized by a high disability rate and an unfavorable prognosis. It has often been underdiagnosed and misdiagnosed as idiopathic transverse myelitis (ITM). This study aimed to describe the clinical features, radiological biomarkers, treatments, and functional ...
Zeqiang Ji, Jianlong Zhang, Yiming Shi, Shiyu Shan, Yang Du, Guangshuo Li, Ying Jin, Yani Zhang, Chuanying Wang, Yijun Lin, Yuhao Guo, Decai Tian, Xingquan Zhao, Tian Song   +13 more
wiley   +1 more source

Personalized Approach as a Basis for the Future Diagnosis of Tuberculosis (Literature Review)

Acta Biomedica Scientifica, 2019
The global spread of tuberculosis remains one of actual problems of public health despite of introduction of public health safety programs. Early, rapid and accurate identification of M. tuberculosis and determination of drug susceptibility are essential
P. A. Khromova, V. V. Sinkov, E. D. Savilov   +2 more
doaj   +1 more source

Transcriptional Biomarkers of Differentially Detectable Mycobacterium tuberculosis in Patient Sputum

mBio, 2022
Certain populations of Mycobacterium tuberculosis go undetected by standard diagnostics but can be enumerated using limiting dilution assays. These differentially detectable M. tuberculosis (DD M.
Kayvan Zainabadi, Kohta Saito, Saurabh Mishra, Kathleen Frances Walsh, Laurent Daniel Mathurin, Stalz Charles Vilbrun, Oksana Ocheretina, Jean William Pape, Daniel W. Fitzgerald, Carl F. Nathan, Myung Hee Lee   +10 more
doaj   +1 more source

Changes in Mycobacterium tuberculosis genotype families over 20 years in a population-based study in Northern Malawi. [PDF]

, 2010
BACKGROUND: Despite increasing interest in possible differences in virulence and transmissibility between different genotypes of M. tuberculosis, very little is known about how genotypes within a population change over decades, or about relationships to ...
Houben, Rein M, Judith R. Glynn, Fine, Paul E.M., McNerney, Ruth, Glynn, Judith R., Neil French, Glynn, Judith R, French, Neil, Crampin, Amelia C, Rein M Houben, Paul E M Fine, Mallard, Kim, Judith R Glynn, Amelia C Crampin, Amelia C. Crampin, Paul E. M. Fine, Fine, Paul EM, Munthali, Lumbani, Crampin, Amelia C., Saad Alghamdi, Ruth McNerney, Lumbani Munthali, Alghamdi, Saad, Ndlovu, Richard, Rein M. Houben, Kim Mallard, Richard Ndlovu, Houben, Rein M.   +27 more
core   +1 more source

Innate Immune Reprogramming Mediated by Endogenous Retroelement Dysregulation Drives Multiple Sclerosis Progression

Annals of Clinical and Translational Neurology, EarlyView.
Epigenetic reprogramming in hematopoietic stem and progenitor cells (HSPCs) and downstream myeloid cells, mediated by H3.3 downregulation and endogenous retroelement (ERE) overexpression, contributes to the progression of multiple sclerosis (MS). ABSTRACT Background Skewed myelopoiesis in the bone marrow has been identified as a key driver of multiple ...
Li‐Mei Xiao, Qiu‐Ping Zhao, Run‐Yun Li, Wei Chen, Huan‐Huan Song, Wan‐Jin Chen, Ying Fu   +6 more
wiley   +1 more source

Conceptualising quality early childhood education: Learning from young children in Brazil and South Africa through creative and play‐based methods

British Educational Research Journal, EarlyView., 2023
Abstract Early childhood has increasingly been acknowledged as a vital time for all children. Inclusive and quality education is part of the United Nations Sustainable Development Goals, with the further specification that all children have access to quality pre‐primary education.
Laura H. V. Wright, Irene Rizzini, Malibongwe Gwele, Lynn McNair, Cristina Laclette Porto, Marsha Orgill, E. Kay M. Tisdall, Malcolm Bush, Linda Biersteker   +8 more
wiley   +1 more source

Tuberculosis diagnostics and biomarkers: needs, challenges, recent advances, and opportunities

, 2012
Tuberculosis is unique among the major infectious diseases in that it lacks accurate rapid point-of-care diagnostic tests. Failure to control the spread of tuberculosis is largely due to our inability to detect and treat all infectious cases of pulmonary
Grobusch, Martin P., Pletschette, Michel, Mchugh, Timothy D., Schwank, Samana, Zumla, A, McNerney, R., Squire, S. Bertel, Ford, Nathan, Kim, P.S., Marais, B, Squire, S B, Migliori, Giovanni Batista, Bates, M, McHugh, Timothy D, Grobusch, M.P., McNerney, R, Migliori, G-B, Migliori, Giovanni-Batista, Squire, Bertie, Lawn, S, O'Grady, J, Chakaya, J., Lawn, Steve, Mwaba, Peter, Harari, Alexandre, Memish, Z, Harari, A., Cox, Helen, Abubakar, I, Ford, N, Hoelscher, Michael, Chakaya, J, Kim, Peter, Zijenah, L, Casenghi, M., Grobusch, M P, Casenghi, Martina, McHugh, T D, Marais, B., Weyer, K., Pantaleo, Giuseppe, Schito, Marco, Pletschette, M, Abubakar, Ibrahim, Atun, Rifat, Weyer, K, Mchugh, Timothy, O'Grady, J., Schwank, S, Mwaba, P., Grobusch, Martin P, Mwaba, P, Casenghi, M, Lawn, S., Squire, S, Zijenah, L., Ditui, Lucica, Cox, H., Pantaleo, G, Kim, P S, Schito, M, Weyer, Karin, O'Grady, Justin, Atun, R, Kim, Peter S, Harari, A, Grobusch, Martin, Abubakar, I., Zijenah, Lynn, Bates, Matthew, Memish, Ziad, Cox, H, Pletschette, M., Memish, Z., Schwank, S., Squire, S Bertel, Migliori, G.B., Ditui, L., McNerney, Ruth, Hoelscher, M., McHugh, T.D., Bates, M., Swaminathan, Soumya, Marais, Ben, Maeurer, Markus, Pantaleo, G., Zumla, A., Maeurer, M, Swaminathan, S, Kim, Peter S., Ditui, L, Hoelscher, M, Squire, S.B., Chakaya, Jeremiah, Ford, N., Zumla, Alimuddin, Schito, M., Maeurer, M., Swaminathan, S., Atun, R.   +99 more
core   +1 more source

Ofatumumab in Myelin Oligodendrocyte Glycoprotein Antibody–Associated Disease: A Comparison With Rituximab

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To evaluate the efficacy and safety of ofatumumab in patients with myelin oligodendrocyte glycoprotein antibody–associated disease (MOGAD), and compare it with rituximab. Methods We conducted a single–center, observational study including 22 MOGAD patients treated with ofatumumab and 21 treated with rituximab.
Yuxin Fan, Lei Zhou, Jingzi ZhangBao, Hongmei Tan, Zhouzhou Wang, Chao Quan   +5 more
wiley   +1 more source