Results 61 to 70 of about 378,588 (317)

Spatio-temporal distribution of Mycobacterium tuberculosis complex strains in Ghana [PDF]

, 2016
BACKGROUND: There is a perception that genomic differences in the species/lineages of the nine species making the Mycobacterium tuberculosis complex (MTBC) may affect the efficacy of distinct control tools in certain geographical areas.
Yeboah-Manu, Dorothy, K. A. Koram (3088575), Asante-Poku, A., S. Osei-Wusu (3088569), I. D. Otchere (3088587), Forson, A., Dorothy Yeboah-Manu (120059), Osei-Wusu, S., Gagneux, Sebastien, Danso, E., A. Forson (3088581), A. Asante-Poku (3088584), I D Otchere, E. Danso (3088578), A Asante-Poku, Asare, P., P Asare, Koram, K. A., S Osei-Wusu, E Danso, Sebastien Gagneux (149824), A Forson, K A Koram, Sebastien Gagneux, P. Asare (3088572), Dorothy Yeboah-Manu, Otchere, I. D.   +26 more
core   +1 more source

Towards the WHO target of zero childhood tuberculosis deaths: an analysis of mortality in 13 locations in Africa and Asia.

, 2013
SETTING: Achieving the World Health Organization (WHO) target of zero paediatric tuberculosis (TB) deaths will require an understanding of the underlying risk factors for mortality.
Russell, GK, Cooke, GS, Merle, CS, Silveira da Fonseca, M, Russell, G K, da Fonseca, M, du Cros, P, Merle, C S, Cooke, G S, Casas, E C, Casas, EC   +10 more
core   +1 more source

Building a Framework for Sexual and Reproductive Health Care in the Rheumatology Context: Content and Approaches

Arthritis Care &Research, EarlyView.
People with systemic autoimmune and rheumatic diseases (SARDs) are at higher risk than the general population of experiencing adverse pregnancy and perinatal outcomes such as preeclampsia, intrauterine growth restriction, and maternal and/or fetal death.
Mehret Birru Talabi, Sonya Borrero
wiley   +1 more source

Treatment results of patients with multiple and extensive drug resistance registered in 2012 in the Russian Federation and in the world

Туберкулез и болезни лёгких, 2016
The chemotherapy results have been analyzed in tuberculosis patients suffering from multiple drug resistance registered for treatment in the Russian Federation in 2011-2012 compared with the treatment outcomes of MDR patients registered for treatment in ...
S. A. Sterlikov, V. V. Testov, I. A. Vasilieva   +2 more
doaj  

Optimization of Lyophilized LAMP and RT-PCR Reaction Mixes for Detection of Tuberculosis

The EuroBiotech Journal, 2020
Undoubtedly, one of the most infectious diseases in the world is tuberculosis. Key factor for tuberculosis control is to prevent possible contagion with rapid diagnosis and effective treatment.
Agel Esra, Sagcan Hasan
doaj   +1 more source

Acute and persistent Mycobacterium tuberculosis infections depend on the thiol peroxidase TpX.

, 2009
The macrophage is the natural niche of Mycobacterium tuberculosis infection. In order to combat oxidative and nitrosative stresses and persist in macrophages successfully, M. tuberculosis is endowed with a very efficient antioxidant complex.
Hu, Y, Yanmin Hu, Anthony R M Coates, Anthony R. M. Coates, Coates, AR   +4 more
core   +1 more source

Development and optimization of a gas chromatography/mass spectrometry method for the analysis of thermochemolytic degradation products of phthiocerol dimycocerosate waxes found in Mycobacterium tuberculosis. [PDF]

, 2013
RATIONALE: The phthiocerol dimycocerosates (PDIMs) are certain stable and hydrophobic waxes found in the cell membrane of Mycobacterium tuberculosis, bacteria that cause an infectious disease of growing concern worldwide.
O'Sullivan, Denise M., Minnikin, David E, O'Sullivan, Denise M, Minnikin, David E., Wright, Ian P., McNerney, Ruth, Lee, Oona CY, Morgan, Geraint H, Pillinger, Colin T., Nicoara, Simona C., Lee, Oona C. Y., Morgan, Geraint H., Pillinger, Collin T, Nicoara, Simona C, Wright, Ian P   +14 more
core   +1 more source

Bacteria‐Responsive Nanostructured Drug Delivery Systems for Targeted Antimicrobial Therapy

Advanced Materials, EarlyView.
Bacteria‐responsive nanocarriers are designed to release antimicrobials only in the presence of infection‐specific cues. This selective activation ensures drug release precisely at the site of infection, avoiding premature or indiscriminate release, and enhancing efficacy.
Guillermo Landa, Gracia Mendoza, Silvia Irusta, Manuel Arruebo   +3 more
wiley   +1 more source

A highly conserved transcriptional repressor controls a large regulon involved in lipid degradation in Mycobacterium smegmatis and Mycobacterium tuberculosis. [PDF]

, 2007
The Mycobacterium tuberculosis TetR-type regulator Rv3574 has been implicated in pathogenesis as it is induced in vivo, and genome-wide essentiality studies show it is required for infection.
Withers, Mike, Moreland, NJ, Sidders, B, Ben Sidders, Catherine N. Soffair, Besra, Gurdyal; id_orcid, ten Bokum, A, Ten Bokum, A M C, Kendall, Sharon L, Soffair, CN, Sudagar Gurcha, Stoker, NG, Rosangela Frita, Gurdyal S. Besra, Besra, G S, Moreland, Nicole J, Moreland, N J, Kendall, SL, J. Shaun Lott, Sidders, Ben, Frita, R, Soffair, Catherine N, Neil G. Stoker, Frita, Rosangela, Soffair, C N, Mike Withers, Gurcha, S, Stoker, N G, Nicole J. Moreland, Auckland, Sydney, Birmingham, Gurcha, Sudagar, Sharon L. Kendall, Lott, J Shaun, Kendall, S L, Stoker, Neil G, Lott, J S, Ten Bokum, Annemieke, Withers, M, Lott, JS, Annemieke Ten Bokum, Besra, Gurdyal S   +41 more
core   +1 more source

RNA Helicase DDX21 Controls CD4+ T Cell Proliferation and Promotes Inflammatory Bowel Disease via Translational Control

Advanced Science, EarlyView.
ABSTRACT Inflammatory bowel disease (IBD) is characterized by dysregulated T cell responses. RNA helicases, including DExD‐box helicase 21 (DDX21), are pivotal in RNA metabolism, but their role in T cell‐mediated pathology during IBD remains unclear. Here, we demonstrate that DDX21 expression in CD4+ T cells correlates with cell cycle and translation ...
Yujuan Zhang, Chen Kan, Xinhui Yang, Yajuan Hao, Xuemin Cai, Mei Yang, Qianqian Zhang, Zhengting Wang, Ning Jiang, Lei Wang, Hua‐Bing Li, Jing Zhou   +11 more
wiley   +1 more source